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7W99
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BU of 7w99 by Molmil
SARS-CoV-2 Delta S-ACE2-C2a
Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein
Authors:Cong, Y, Liu, C.X.
Deposit date:2021-12-09
Release date:2022-01-12
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies.
Nat Commun, 13, 2022
7W9F
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BU of 7w9f by Molmil
SARS-CoV-2 Delta S-RBD-8D3
Descriptor: Spike protein S1, The heavy chain of 8D3, The light chain of 8D3
Authors:Cong, Y, Liu, C.X.
Deposit date:2021-12-09
Release date:2022-01-12
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies.
Nat Commun, 13, 2022
7W9I
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BU of 7w9i by Molmil
SARS-CoV-2 Delta S-RBD-ACE2
Descriptor: Angiotensin-converting enzyme 2, Spike protein S1
Authors:Cong, Y, Liu, C.X.
Deposit date:2021-12-09
Release date:2022-01-12
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies.
Nat Commun, 13, 2022
7W94
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BU of 7w94 by Molmil
Transition state of SARS-CoV-2 Delta variant spike protein
Descriptor: Spike glycoprotein
Authors:Cong, Y, Liu, C.X.
Deposit date:2021-12-09
Release date:2022-01-12
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies.
Nat Commun, 13, 2022
7W9C
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BU of 7w9c by Molmil
SARS-CoV-2 Delta S-ACE2-C3
Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein
Authors:Cong, Y, Liu, C.X.
Deposit date:2021-12-09
Release date:2022-01-12
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies.
Nat Commun, 13, 2022
7W98
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BU of 7w98 by Molmil
SARS-CoV-2 Delta S-ACE2-C1
Descriptor: Angiotensin-converting enzyme 2, Spike glycoprotein
Authors:Cong, Y, Liu, C.X.
Deposit date:2021-12-09
Release date:2022-01-12
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies.
Nat Commun, 13, 2022
7WK0
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BU of 7wk0 by Molmil
Local refine of Omicron spike bitrimer with 6m6 antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6m6 heavy chain, 6m6 light chain, ...
Authors:Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
Deposit date:2022-01-08
Release date:2022-07-13
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding.
Cell Res., 32, 2022
7WJY
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BU of 7wjy by Molmil
Omicron spike trimer with 6m6 antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6m6 heavy chain, 6m6 light chain, ...
Authors:Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
Deposit date:2022-01-08
Release date:2022-07-13
Last modified:2022-09-14
Method:ELECTRON MICROSCOPY (3.24 Å)
Cite:A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding.
Cell Res., 32, 2022
7WJZ
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BU of 7wjz by Molmil
Omicron Spike bitrimer with 6m6 antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 6m6 heavy chain, 6m6 light chain, ...
Authors:Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L.
Deposit date:2022-01-08
Release date:2022-07-13
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3.34 Å)
Cite:A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding.
Cell Res., 32, 2022
7WOS
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BU of 7wos by Molmil
The state 3 of Omicron Spike with bispecific antibody FD01
Descriptor: 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ...
Authors:Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L.
Deposit date:2022-01-22
Release date:2022-11-30
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
7WOP
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BU of 7wop by Molmil
The local refined map of Omicron spike with bispecific antibody FD01
Descriptor: 16L9, GW01, Spike protein S1
Authors:Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L.
Deposit date:2022-01-22
Release date:2022-11-30
Method:ELECTRON MICROSCOPY (3.51 Å)
Cite:Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
7WOR
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BU of 7wor by Molmil
The state 2 of Omicron Spike with bispecific antibody FD01
Descriptor: 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ...
Authors:Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L.
Deposit date:2022-01-22
Release date:2022-11-30
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
7WOV
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BU of 7wov by Molmil
The state 5 of Omicron Spike with bispecific antibody FD01
Descriptor: 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ...
Authors:Zhang, X, Zhan, W.Q, Sun, L, Chen, Z.G.
Deposit date:2022-01-22
Release date:2022-11-30
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
7WOW
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BU of 7wow by Molmil
The state 6 of Omicron Spike with bispecific antibody FD01
Descriptor: 16L9 Fv, GW01 Fv, Spike glycoprotein
Authors:Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L.
Deposit date:2022-01-22
Release date:2022-11-30
Method:ELECTRON MICROSCOPY (6.11 Å)
Cite:Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
7WOU
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BU of 7wou by Molmil
The state 4 of Omicron Spike with bispecific antibody FD01
Descriptor: 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ...
Authors:Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L.
Deposit date:2022-01-22
Release date:2022-11-30
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
7WOQ
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BU of 7woq by Molmil
The state 1 of Omicron Spike with bispecific antibody FD01
Descriptor: 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L.
Deposit date:2022-01-22
Release date:2022-11-30
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies
Cell Discov, 8, 2022
7VGG
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BU of 7vgg by Molmil
Cryo-EM structure of Ultraviolet-B activated UVR8 in complex with COP1
Descriptor: E3 ubiquitin-protein ligase COP1, Ultraviolet-B receptor UVR8
Authors:Wang, Y.D, Wang, L.X, Guan, Z.Y, Yin, P.
Deposit date:2021-09-16
Release date:2022-05-04
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insight into UV-B-activated UVR8 bound to COP1.
Sci Adv, 8, 2022
8WYS
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BU of 8wys by Molmil
Local map of human CD5L bound to IgM-Fc/J
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Wang, Y.X, Su, C, Xiao, J.Y.
Deposit date:2023-10-31
Release date:2024-10-09
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:CD5L associates with IgM via the J chain.
Nat Commun, 15, 2024
8WYR
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BU of 8wyr by Molmil
Cryo-EM structure of human CD5L bound to IgM-Fc/J
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Wang, Y.X, Su, C, Xiao, J.Y.
Deposit date:2023-10-31
Release date:2024-10-09
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:CD5L associates with IgM via the J chain.
Nat Commun, 15, 2024
7WEV
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BU of 7wev by Molmil
SARS-COV-2 BETA VARIANT SPIKE PROTEIN IN TRANSITION STATE
Descriptor: Spike glycoprotein
Authors:Xu, C, Cong, Y.
Deposit date:2021-12-24
Release date:2022-01-26
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Conformational dynamics of the Beta and Kappa SARS-CoV-2 spike proteins and their complexes with ACE2 receptor revealed by cryo-EM.
Nat Commun, 12, 2021
4QOC
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BU of 4qoc by Molmil
crystal structure of compound 16 bound to MDM2(17-111), {(3R,5R,6S)-5-(3-CHLOROPHENYL)-6-(4-CHLOROPHENYL)-1-[(1S)-1-CYCLOPROPYL-2-(PYRROLIDIN-1-YLSULFONYL)ETHYL]-3-METHYL-2-OXOPIPERIDIN-3-YL}ACETIC ACID
Descriptor: E3 ubiquitin-protein ligase Mdm2, {(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(1S)-1-cyclopropyl-2-(pyrrolidin-1-ylsulfonyl)ethyl]-3-methyl-2-oxopiperidin-3-yl}acetic acid
Authors:Huang, X.
Deposit date:2014-06-19
Release date:2015-05-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Optimization beyond AMG 232: discovery and SAR of sulfonamides on a piperidinone scaffold as potent inhibitors of the MDM2-p53 protein-protein interaction.
Bioorg.Med.Chem.Lett., 24, 2014
3RYT
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BU of 3ryt by Molmil
The Plexin A1 intracellular region in complex with Rac1
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plexin-A1, ...
Authors:Zhang, X, He, H.
Deposit date:2011-05-11
Release date:2012-01-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.582 Å)
Cite:Plexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced Dimerization.
Sci.Signal., 5, 2012
5EKJ
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BU of 5ekj by Molmil
Human Carbonic Anhydrase II complexed with a two-faced guest
Descriptor: 2-(butylamino)-~{N}-[2-(4-sulfamoylphenyl)ethyl]ethanamide, Carbonic anhydrase 2, GLYCEROL, ...
Authors:Roose, B.W, Dmochowski, I.J.
Deposit date:2015-11-03
Release date:2016-01-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.129 Å)
Cite:Programming A Molecular Relay for Ultrasensitive Biodetection through (129) Xe NMR.
Angew.Chem.Int.Ed.Engl., 55, 2016
5EKH
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BU of 5ekh by Molmil
Human Carbonic Anhydrase II complexed with a two-faced guest
Descriptor: 4-(butylaminomethyl)benzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ...
Authors:Roose, B.W, Dmochowksi, I.J.
Deposit date:2015-11-03
Release date:2016-01-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Programming A Molecular Relay for Ultrasensitive Biodetection through (129) Xe NMR.
Angew.Chem.Int.Ed.Engl., 55, 2016
5EKM
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BU of 5ekm by Molmil
Human Carbonic Anhydrase II complexed with a two-faced guest
Descriptor: 2-(butylamino)-~{N}-(4-sulfamoylphenyl)ethanamide, Carbonic anhydrase 2, GLYCEROL, ...
Authors:Roose, B.W, Dmochowski, I.J.
Deposit date:2015-11-03
Release date:2016-01-06
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Programming A Molecular Relay for Ultrasensitive Biodetection through (129) Xe NMR.
Angew.Chem.Int.Ed.Engl., 55, 2016

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