2JHE
 
 | | N-terminal domain of TyrR transcription factor (residues 1 - 190) | | Descriptor: | 2-(2-ETHOXYETHOXY)ETHANOL, SULFATE ION, TETRAETHYLENE GLYCOL, ... | | Authors: | Verger, D, Carr, P.D, Kwok, T, Ollis, D.L. | | Deposit date: | 2007-02-21 | | Release date: | 2008-06-24 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of the N-Terminal Domain of the Tyrr Transcription Factor Responsible for Gene Regulation of Aromatic Amino Acid Biosynthesis and Transport in Escherichia Coli K12
J.Mol.Biol., 367, 2007
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1ZI8
 | | Crystal Structure Analysis of the dienelactone hydrolase mutant(E36D, C123S, A134S, S208G, A229V, K234R)- 1.4 A | | Descriptor: | Carboxymethylenebutenolidase, GLYCEROL, SULFATE ION | | Authors: | Kim, H.-K, Liu, J.-W, Carr, P.D, Ollis, D.L. | | Deposit date: | 2005-04-27 | | Release date: | 2005-07-05 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase.
Acta Crystallogr.,Sect.D, 61, 2005
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1ZIY
 | | Crystal Structure Analysis of the dienelactone hydrolase mutant (C123S) bound with the PMS moiety of the protease inhibitor, Phenylmethylsulfonyl fluoride (PMSF)- 1.9 A | | Descriptor: | Carboxymethylenebutenolidase, GLYCEROL, SULFATE ION | | Authors: | Kim, H.-K, Liu, J.-W, Carr, P.D, Ollis, D.L. | | Deposit date: | 2005-04-27 | | Release date: | 2005-07-05 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase.
Acta Crystallogr.,Sect.D, 61, 2005
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2GUI
 | | Structure and Function of Cyclized Versions of the Proofreading Exonuclease Subunit of E. coli DNA Polymerase III | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA polymerase III epsilon subunit, ... | | Authors: | Park, A.Y, Carr, P.D, Ollis, D.L, Dixon, N.E. | | Deposit date: | 2006-04-30 | | Release date: | 2007-03-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structure and Function of Cyclized Versions of the Proofreading Exonuclease Subunit E. coli DNA Polymerase III
To be Published
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1ZI6
 | | Crystal Structure Analysis of the dienelactone hydrolase (C123S) mutant- 1.7 A | | Descriptor: | Carboxymethylenebutenolidase, GLYCEROL, SULFATE ION | | Authors: | Kim, H.-K, Liu, J.-W, Carr, P.D, Ollis, D.L. | | Deposit date: | 2005-04-27 | | Release date: | 2005-07-05 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase.
Acta Crystallogr.,Sect.D, 61, 2005
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1ZIX
 | | Crystal Structure Analysis of the dienelactone hydrolase mutant (E36D, R105H, C123S, G211D, K234N)- 1.8 A | | Descriptor: | Carboxymethylenebutenolidase, GLYCEROL | | Authors: | Kim, H.-K, Liu, J.-W, Carr, P.D, Ollis, D.L. | | Deposit date: | 2005-04-27 | | Release date: | 2005-07-05 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase.
Acta Crystallogr.,Sect.D, 61, 2005
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1ZI9
 | | Crystal Structure Analysis of the dienelactone hydrolase (E36D, C123S) mutant- 1.5 A | | Descriptor: | Carboxymethylenebutenolidase, GLYCEROL, SULFATE ION | | Authors: | Kim, H.-K, Liu, J.-W, Carr, P.D, Ollis, D.L. | | Deposit date: | 2005-04-27 | | Release date: | 2005-07-05 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase.
Acta Crystallogr.,Sect.D, 61, 2005
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1ZJ4
 | | Crystal Structure Analysis of the dienelactone hydrolase mutant (E36D, C123S) bound with the PMS moiety of the protease inhibitor, Phenylmethylsulfonyl fluoride (PMSF)- 1.7 A | | Descriptor: | Carboxymethylenebutenolidase, GLYCEROL, SULFATE ION | | Authors: | Kim, H.-K, Liu, J.-W, Carr, P.D, Ollis, D.L. | | Deposit date: | 2005-04-28 | | Release date: | 2005-07-05 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase.
Acta Crystallogr.,Sect.D, 61, 2005
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2GNK
 | | GLNK, A SIGNAL PROTEIN FROM E. COLI | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, PROTEIN (NITROGEN REGULATORY PROTEIN) | | Authors: | Xu, Y, Cheah, E, Carr, P.D, van Heeswijk, W.C, Westerhoff, H.V, Vasudevan, S.G, Ollis, D.L. | | Deposit date: | 1998-07-14 | | Release date: | 1999-07-23 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | GlnK, a PII-homologue: structure reveals ATP binding site and indicates how the T-loops may be involved in molecular recognition.
J.Mol.Biol., 282, 1998
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2D2J
 | | OpdA from Agrobacterium radiobacter without inhibitor/product present at 1.75 A resolution | | Descriptor: | 1,2-ETHANEDIOL, COBALT (II) ION, phosphotriesterase | | Authors: | Jackson, C, Kim, H.K, Carr, P.D, Liu, J.W, Ollis, D.L. | | Deposit date: | 2005-09-09 | | Release date: | 2005-09-20 | | Last modified: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism
Biochim.Biophys.Acta, 1752, 2005
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2D2G
 | | OpdA from Agrobacterium radiobacter with bound product dimethylthiophosphate | | Descriptor: | COBALT (II) ION, O,O-DIMETHYL HYDROGEN THIOPHOSPHATE, phosphotriesterase | | Authors: | Jackson, C, Kim, H.K, Carr, P.D, Liu, J.W, Ollis, D.L. | | Deposit date: | 2005-09-08 | | Release date: | 2005-09-20 | | Last modified: | 2025-03-26 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism
Biochim.Biophys.Acta, 1752, 2005
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4L9X
 | | Triazine hydrolase from Arthobacter aurescens modified for maximum expression in E.coli | | Descriptor: | ACETATE ION, Triazine hydrolase | | Authors: | Jackson, C.J, Coppin, C.W, Alexandrov, A, Wilding, M, Liu, J.-W, Ubels, J, Paks, M, Carr, P.D, Newman, J, Russell, R.J, Field, M, Weik, M, Oakeshott, J.G, Scott, C. | | Deposit date: | 2013-06-18 | | Release date: | 2014-05-21 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | 300-Fold increase in production of the Zn2+-dependent dechlorinase TrzN in soluble form via apoenzyme stabilization.
Appl.Environ.Microbiol., 80, 2014
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1J53
 | | Structure of the N-terminal Exonuclease Domain of the Epsilon Subunit of E.coli DNA Polymerase III at pH 8.5 | | Descriptor: | 1,2-ETHANEDIOL, DNA polymerase III, epsilon chain, ... | | Authors: | Hamdan, S, Carr, P.D, Brown, S.E, Ollis, D.L, Dixon, N.E. | | Deposit date: | 2002-01-22 | | Release date: | 2002-10-16 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Basis for Proofreading during Replication of the Escherichia coli Chromosome
Structure, 10, 2002
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2ZO9
 | | Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal ion preference | | Descriptor: | FE (II) ION, MALONATE ION, Phosphohydrolase | | Authors: | Jackson, C.J, Carr, P.D, Ollis, D.L. | | Deposit date: | 2008-05-07 | | Release date: | 2008-10-07 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference.
Acta Crystallogr.,Sect.F, 64, 2008
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3A3W
 | | Structure of OpdA mutant (G60A/A80V/S92A/R118Q/K185R/Q206P/D208G/I260T/G273S) with diethyl 4-methoxyphenyl phosphate bound in the active site | | Descriptor: | COBALT (II) ION, DIETHYL 4-METHOXYPHENYL PHOSPHATE, Phosphotriesterase | | Authors: | Ollis, D.L, Tawfik, D.S, Schenk, G, Jackson, C.J, Foo, J.L, Tokuriki, N, Afriat, L, Carr, P.D, Kim, H.K. | | Deposit date: | 2009-06-23 | | Release date: | 2010-01-12 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase
Proc.Natl.Acad.Sci.USA, 2009
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1J54
 | | Structure of the N-terminal exonuclease domain of the epsilon subunit of E.coli DNA polymerase III at pH 5.8 | | Descriptor: | 1,2-ETHANEDIOL, DNA polymerase III, epsilon chain, ... | | Authors: | Hamdan, S, Carr, P.D, Brown, S.E, Ollis, D.L, Dixon, N.E. | | Deposit date: | 2002-01-22 | | Release date: | 2002-10-16 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural Basis for Proofreading during Replication of the Escherichia coli Chromosome
Structure, 10, 2002
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3A3X
 | | Structure of OpdA mutant (G60A/A80V/R118Q/K185R/Q206P/D208G/I260T/G273S) | | Descriptor: | COBALT (II) ION, Phosphotriesterase | | Authors: | Ollis, D.L, Tawfik, D.S, Schenk, G, Jackson, C.J, Foo, J.L, Tokuriki, N, Afriat, L, Carr, P.D, Kim, H.K. | | Deposit date: | 2009-06-23 | | Release date: | 2010-01-12 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase
Proc.Natl.Acad.Sci.USA, 2009
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6BM9
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6BQE
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2ZOA
 | | Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) COLLECTED AT 1.280 ANGSTROM | | Descriptor: | FE (II) ION, MALONATE ION, Phosphohydrolase | | Authors: | Ollis, D.L, Jackson, C.J, Carr, P.D. | | Deposit date: | 2008-05-07 | | Release date: | 2008-10-07 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Malonate-bound structure of the glycerophosphodiesterase from Enterobacter aerogenes (GpdQ) and characterization of the native Fe2+ metal-ion preference.
Acta Crystallogr.,Sect.F, 64, 2008
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3C86
 | | OpdA from agrobacterium radiobacter with bound product diethyl thiophosphate from crystal soaking with tetraethyl dithiopyrophosphate- 1.8 A | | Descriptor: | 1,2-ETHANEDIOL, COBALT (II) ION, FE (II) ION, ... | | Authors: | Ollis, D.L, Jackson, C.J, Foo, J.L, Kim, H.K, Carr, P.D, Liu, J.W, Salem, G. | | Deposit date: | 2008-02-10 | | Release date: | 2008-02-19 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase
J.Mol.Biol., 375, 2008
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3A4J
 | | arPTE (K185R/D208G/N265D/T274N) | | Descriptor: | 1,2-ETHANEDIOL, COBALT (II) ION, Phosphotriesterase | | Authors: | Foo, J.L, Jackson, C.J, Carr, P.D, Ollis, D.L. | | Deposit date: | 2009-07-07 | | Release date: | 2010-01-12 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase
Proc.Natl.Acad.Sci.USA, 2009
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1GGV
 | | CRYSTAL STRUCTURE OF THE C123S MUTANT OF DIENELACTONE HYDROLASE (DLH) BOUND WITH THE PMS MOIETY OF THE PROTEASE INHIBITOR, PHENYLMETHYLSULFONYL FLUORIDE (PMSF) | | Descriptor: | DIENELACTONE HYDROLASE | | Authors: | Robinson, A, Edwards, K.J, Carr, P.D, Barton, J.D, Ewart, G.D, Ollis, D.L. | | Deposit date: | 2000-09-27 | | Release date: | 2000-12-13 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of the C123S mutant of dienelactone hydrolase (DLH) bound with the PMS moiety of the protease inhibitor phenylmethylsulfonyl fluoride (PMSF).
Acta Crystallogr.,Sect.D, 56, 2000
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1GNK
 | | GLNK, A SIGNAL PROTEIN FROM E. COLI | | Descriptor: | PROTEIN (GLNK), SULFATE ION | | Authors: | Xu, Y, Cheah, E, Carr, P.D, Vanheeswijk, W.C, Westerhoff, H.V, Vasudevan, S.G, Ollis, D.L. | | Deposit date: | 1998-07-14 | | Release date: | 1999-07-23 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | GlnK, a PII-homologue: structure reveals ATP binding site and indicates how the T-loops may be involved in molecular recognition.
J.Mol.Biol., 282, 1998
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3D03
 | | 1.9A structure of Glycerophoshphodiesterase (GpdQ) from Enterobacter aerogenes | | Descriptor: | COBALT (II) ION, Phosphohydrolase | | Authors: | Hadler, K.S, Tanifum, E, Yip, S.H.-C, Miti, N, Guddat, L.W, Jackson, C.J, Gahan, L.R, Carr, P.D, Nguyen, K, Ollis, D.L, Hengge, A.C, Larrabee, J.A, Schenk, G. | | Deposit date: | 2008-04-30 | | Release date: | 2008-10-14 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes.
J.Am.Chem.Soc., 130, 2008
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