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3BZ3
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BU of 3bz3 by Molmil
Crystal Structure Analysis of Focal Adhesion Kinase with a Methanesulfonamide Diaminopyrimidine Inhibitor
Descriptor: Focal adhesion kinase 1, N-methyl-N-{3-[({2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide
Authors:Vajdos, F, Marr, E.
Deposit date:2008-01-17
Release date:2008-04-01
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271.
Cancer Res., 68, 2008
3S84
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BU of 3s84 by Molmil
Dimeric apoA-IV
Descriptor: Apolipoprotein A-IV, SULFATE ION
Authors:Deng, X, Davidson, W.S, Thompson, T.B.
Deposit date:2011-05-27
Release date:2012-05-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of Dimeric Apolipoprotein A-IV and Its Mechanism of Self-Association.
Structure, 20, 2012
3BCE
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BU of 3bce by Molmil
Crystal structure of the ErbB4 kinase
Descriptor: DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, Receptor tyrosine-protein kinase erbB-4, ...
Authors:Qiu, C.
Deposit date:2007-11-12
Release date:2008-02-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of Activation and Inhibition of the HER4/ErbB4 Kinase.
Structure, 16, 2008
3BBW
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BU of 3bbw by Molmil
crystal structure of the ErbB4 kinase in its inactive conformation
Descriptor: Receptor tyrosine-protein kinase erbB-4
Authors:Qiu, C.
Deposit date:2007-11-11
Release date:2008-02-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4 Å)
Cite:Mechanism of Activation and Inhibition of the HER4/ErbB4 Kinase.
Structure, 16, 2008
3EJ0
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BU of 3ej0 by Molmil
Crystal structure of inorganic pyrophosphatase from burkholderia pseudomallei with bound N-(pyridin-3-ylmethyl) aniline, H32 crystal form
Descriptor: Inorganic pyrophosphatase, N-(pyridin-3-ylmethyl)aniline
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-09-17
Release date:2008-09-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:The role of medical structural genomics in discovering new drugs for infectious diseases.
PLoS Comput Biol, 5, 2009
3TN2
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BU of 3tn2 by Molmil
structure analysis of MIP1-beta P8A
Descriptor: C-C motif chemokine 4, ZINC ION
Authors:Guo, Q, Tang, W.J.
Deposit date:2011-09-01
Release date:2012-09-05
Last modified:2018-08-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme.
J.Mol.Biol., 427, 2015
3EIY
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BU of 3eiy by Molmil
Crystal structure of inorganic pyrophosphatase from burkholderia pseudomallei with bound pyrophosphate
Descriptor: DI(HYDROXYETHYL)ETHER, Inorganic pyrophosphatase, POTASSIUM ION, ...
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2008-09-17
Release date:2008-09-30
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The role of medical structural genomics in discovering new drugs for infectious diseases.
PLoS Comput Biol, 5, 2009
1UG4
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BU of 1ug4 by Molmil
Crystal Structure of Cardiotoxin VI from Taiwan Cobra (Naja atra) Venom
Descriptor: Cytotoxin 6
Authors:Chung, F.-Y, Wu, W.-G, Chen, C.-J.
Deposit date:2003-06-12
Release date:2005-02-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural difference between group I and group II cobra cardiotoxins: X-ray, NMR, and CD analysis of the effect of cis-proline conformation on three-fingered toxins.
Biochemistry, 44, 2005
1UYA
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BU of 1uya by Molmil
THE SOLUTION STRUCTURE OF THE A-FORM OF UROGUANYLIN-16 NMR, 10 STRUCTURES
Descriptor: UROGUANYLIN-16, ISOMER A
Authors:Marx, U.C, Adermann, K, Forssmann, W.-G, Roesch, P.
Deposit date:1997-09-11
Release date:1998-03-18
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:One peptide, two topologies: structure and interconversion dynamics of human uroguanylin isomers.
J.Pept.Res., 52, 1998
1UYB
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BU of 1uyb by Molmil
THE SOLUTION STRUCTURE OF THE B-FORM OF UROGUANYLIN-16 NMR, 10 STRUCTURES
Descriptor: UROGUANYLIN-16, ISOMER B
Authors:Marx, U.C, Adermann, K, Forssmann, W.-G, Roesch, P.
Deposit date:1997-09-11
Release date:1998-03-18
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:One peptide, two topologies: structure and interconversion dynamics of human uroguanylin isomers.
J.Pept.Res., 52, 1998
1T7I
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BU of 1t7i by Molmil
The structural and thermodynamic basis for the binding of TMC114, a next-generation HIV-1 protease inhibitor.
Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, PHOSPHATE ION, ...
Authors:King, N.M, Prabu-Jeyabalan, M, Nalivaika, E.A, Wigerinck, P.B.T.P, De Bethune, M.-P, Schiffer, C.A.
Deposit date:2004-05-10
Release date:2005-05-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor
J.Med.Chem., 48, 2005
1X9G
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BU of 1x9g by Molmil
PUTATIVE MAR1 RIBONUCLEASE FROM LEISHMANIA DONOVANI
Descriptor: PUTATIVE MAR1
Authors:Caruthers, J, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-08-20
Release date:2004-09-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal structures and proposed structural/functional classification of three protozoan proteins from the isochorismatase superfamily.
Protein Sci., 14, 2005
1XN4
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BU of 1xn4 by Molmil
PUTATIVE MAR1 RIBONUCLEASE FROM LEISHMANIA MAJOR
Descriptor: ribonuclease MAR1
Authors:Caruthers, J, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-10-04
Release date:2004-10-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystal structures and proposed structural/functional classification of three protozoan proteins from the isochorismatase superfamily.
Protein Sci., 14, 2005
6AZ2
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BU of 6az2 by Molmil
Crystal structure of Asf1-Fab 12E complex
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A.
Deposit date:2017-09-09
Release date:2018-01-10
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (2.477 Å)
Cite:Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
J. Mol. Biol., 430, 2018
6AYH
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BU of 6ayh by Molmil
Salmonella enterica GusR
Descriptor: 4-nitrophenyl beta-D-glucopyranosiduronic acid, GLYCEROL, TetR family transcriptional regulator
Authors:Little, M.S, Pellock, S.J.
Deposit date:2017-09-08
Release date:2017-12-20
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural basis for the regulation of beta-glucuronidase expression by human gut Enterobacteriaceae.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6AYZ
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BU of 6ayz by Molmil
Crystal structure of Asf1-Fab 12E complex
Descriptor: Fab Heavy Chain, Fab Light Chain, Histone chaperone ASF1
Authors:Bailey, L.J, Kossiakoff, A.A.
Deposit date:2017-09-08
Release date:2018-01-17
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.096 Å)
Cite:Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
J. Mol. Biol., 430, 2018
6AZ6
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BU of 6az6 by Molmil
Streptococcus agalactiae GntR
Descriptor: GntR family transcriptional regulator
Authors:Pellock, S.J, Redinbo, M.R.
Deposit date:2017-09-10
Release date:2017-12-20
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.909 Å)
Cite:Structural basis for the regulation of beta-glucuronidase expression by human gut Enterobacteriaceae.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6AYI
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BU of 6ayi by Molmil
Escherichia coli GusR
Descriptor: 4-nitrophenyl beta-D-glucopyranosiduronic acid, HTH-type transcriptional regulator UidR
Authors:Little, M.S, Pellock, S.J.
Deposit date:2017-09-08
Release date:2017-12-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structural basis for the regulation of beta-glucuronidase expression by human gut Enterobacteriaceae.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
8OOR
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BU of 8oor by Molmil
CryoEM Structure INO80core Hexasome complex Rvb core refinement state2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, ...
Authors:Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
Deposit date:2023-04-05
Release date:2023-07-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.87 Å)
Cite:Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OOK
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BU of 8ook by Molmil
CryoEM Structure INO80core Hexasome complex Arp5 grappler refinement state1
Descriptor: Actin-related protein 5
Authors:Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
Deposit date:2023-04-05
Release date:2023-07-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (5.69 Å)
Cite:Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OO9
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BU of 8oo9 by Molmil
CryoEM Structure INO80core Hexasome complex ATPase-DNA refinement state1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chromatin-remodeling ATPase INO80, DNA strand 1, ...
Authors:Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
Deposit date:2023-04-04
Release date:2023-07-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OOF
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BU of 8oof by Molmil
CryoEM Structure INO80core Hexasome complex Arp5 Ies6 refinement state1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling complex subunit IES6, ...
Authors:Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
Deposit date:2023-04-05
Release date:2023-07-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OOT
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BU of 8oot by Molmil
CryoEM Structure INO80core Hexasome complex Arp5 Ies6 refinement state2
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, Chromatin-remodeling complex subunit IES6, ...
Authors:Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
Deposit date:2023-04-05
Release date:2023-07-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OO7
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BU of 8oo7 by Molmil
CryoEM Structure INO80core Hexasome complex composite model state1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 5, ...
Authors:Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
Deposit date:2023-04-04
Release date:2023-07-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023
8OOA
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BU of 8ooa by Molmil
CryoEM Structure INO80core Hexasome complex Hexasome refinement state1
Descriptor: DNA Strand 2, DNA strand 1, Histone H2A, ...
Authors:Zhang, M, Jungblut, A, Hoffmann, T, Eustermann, S.
Deposit date:2023-04-04
Release date:2023-07-26
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling.
Science, 381, 2023

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