7UJY
| Estrogen receptor alpha ligand binding domain Y537S mutant in complex with a methylated lasofoxifene derivative that enhances estrogen receptor alpha nuclear resonance time | Descriptor: | (5R,6S)-5-(4-{2-[(2R)-2-methylpyrrolidin-1-yl]ethoxy}phenyl)-6-phenyl-5,6,7,8-tetrahydronaphthalen-2-ol, Estrogen receptor | Authors: | Hosfield, D.J, Greene, G.L, Fanning, S.W. | Deposit date: | 2022-03-31 | Release date: | 2022-06-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife, 11, 2022
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7U0Y
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4ONO
| CD1c in complex with PM (phosphomycoketide) | Descriptor: | (4R,8S,16S,20R)-4,8,12,16,20-pentamethylheptacosyl dihydrogen phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin/T-cell surface glycoprotein CD1c/T-cell surface glycoprotein CD1b chimeric protein, ... | Authors: | Roy, S, Adams, E.J. | Deposit date: | 2014-01-28 | Release date: | 2014-10-08 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (2.705 Å) | Cite: | Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by alpha beta T cells. Proc.Natl.Acad.Sci.USA, 111, 2014
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4ONH
| Crystal Structure of DN6 TCR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | Authors: | Roy, S, Adams, E.J. | Deposit date: | 2014-01-28 | Release date: | 2014-10-08 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (3.008 Å) | Cite: | Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by alpha beta T cells. Proc.Natl.Acad.Sci.USA, 111, 2014
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