7ZAZ
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![BU of 7zaz by Molmil](/molmil-images/mine/7zaz) | macrocyclase OphP with ZPP | Descriptor: | 1,2-ETHANEDIOL, BICARBONATE ION, DIMETHYL SULFOXIDE, ... | Authors: | Song, H, Naismith, J.H. | Deposit date: | 2022-03-23 | Release date: | 2022-07-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for the enzymatic macrocyclization of multiply backbone N-methylated peptides Biorxiv, 2022
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7ZB2
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![BU of 7zb2 by Molmil](/molmil-images/mine/7zb2) | apo macrocyclase OphP | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | Authors: | Song, H, Naismith, J.H. | Deposit date: | 2022-03-23 | Release date: | 2022-07-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Molecular basis for the enzymatic macrocyclization of multiply backbone N-methylated peptides Biorxiv, 2022
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7ZB1
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![BU of 7zb1 by Molmil](/molmil-images/mine/7zb1) | S580A with 18mer | Descriptor: | 1,2-ETHANEDIOL, 18mer, BICARBONATE ION, ... | Authors: | Song, H, Naismith, J.H. | Deposit date: | 2022-03-23 | Release date: | 2022-07-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis for the enzymatic macrocyclization of multiply backbone N-methylated peptides Biorxiv, 2022
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7ZB0
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![BU of 7zb0 by Molmil](/molmil-images/mine/7zb0) | macrocyclase OphP with 15mer | Descriptor: | 1,2-ETHANEDIOL, 15mer, BICARBONATE ION, ... | Authors: | Song, H, Naismith, J.H. | Deposit date: | 2022-03-23 | Release date: | 2022-07-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Molecular basis for the enzymatic macrocyclization of multiply backbone N-methylated peptides Biorxiv, 2022
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6QZY
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![BU of 6qzy by Molmil](/molmil-images/mine/6qzy) | full length OphA V406P in complex with SAH | Descriptor: | ASN-GLY-PHE-PRO-TRP-MVA-ILE-MVA-VAL-GLY-PRO-ILE-GLY, MAGNESIUM ION, Peptide N-methyltransferase, ... | Authors: | Song, H, Naismith, J.H. | Deposit date: | 2019-03-12 | Release date: | 2020-04-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Substrate Plasticity of a Fungal Peptide alpha-N-Methyltransferase. Acs Chem.Biol., 15, 2020
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6QZZ
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![BU of 6qzz by Molmil](/molmil-images/mine/6qzz) | full length OphA V404E in complex with SAH | Descriptor: | Peptide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Song, H, Naismith, J.H. | Deposit date: | 2019-03-12 | Release date: | 2020-04-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Substrate Plasticity of a Fungal Peptide alpha-N-Methyltransferase. Acs Chem.Biol., 15, 2020
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6R00
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![BU of 6r00 by Molmil](/molmil-images/mine/6r00) | OphA DeltaC6 V404F complex with SAH | Descriptor: | PHE-PRO-TRP-MVA-ILE-MVA-PHE-GLY-VAL-ILE-GLY-VAL-ILE-GLY, Peptide N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Song, H, Naismith, J.H. | Deposit date: | 2019-03-12 | Release date: | 2020-04-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Substrate Plasticity of a Fungal Peptide alpha-N-Methyltransferase. Acs Chem.Biol., 15, 2020
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6ZRW
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![BU of 6zrw by Molmil](/molmil-images/mine/6zrw) | Crystal structure of the fungal lectin CML1 | Descriptor: | ACETATE ION, GLYCEROL, Mucin-binding lectin 1, ... | Authors: | Bleuler-Martinez, S, Olieric, V, Sharpe, M, Capitani, G, Aebi, M, Kuenzler, M. | Deposit date: | 2020-07-15 | Release date: | 2021-07-28 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structure-function relationship of a novel fucoside-binding fruiting body lectin from Coprinopsis cinerea exhibiting nematotoxic activity. Glycobiology, 32, 2022
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6ZU2
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![BU of 6zu2 by Molmil](/molmil-images/mine/6zu2) | CML1 crystal structure in complex with H-type 1 trisaccharide | Descriptor: | Mucin-binding lectin 1, SULFATE ION, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Varrot, A, Bleuler-Martinez, S. | Deposit date: | 2020-07-21 | Release date: | 2021-07-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure-function relationship of a novel fucoside-binding fruiting body lectin from Coprinopsis cinerea exhibiting nematotoxic activity. Glycobiology, 32, 2022
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6ZV5
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![BU of 6zv5 by Molmil](/molmil-images/mine/6zv5) | CML1 crystal structure in complex with Lewis a tetrasaccharide | Descriptor: | Mucin-binding lectin 1, SULFATE ION, beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Varrot, A, Bleuler-Martinez, S. | Deposit date: | 2020-07-24 | Release date: | 2021-08-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure-function relationship of a novel fucoside-binding fruiting body lectin from Coprinopsis cinerea exhibiting nematotoxic activity. Glycobiology, 32, 2022
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3N0K
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![BU of 3n0k by Molmil](/molmil-images/mine/3n0k) | Proteinase inhibitor from Coprinopsis cinerea | Descriptor: | Serine protease inhibitor 1 | Authors: | Renko, M, Sabotic, J, Bleuler-Martinez, S, Kallert, S, Avanzo, P, Kos, J, Aebi, M, Kuenzler, M, Turk, D. | Deposit date: | 2010-05-14 | Release date: | 2011-06-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Basis of Trypsin Inhibition and Entomotoxicity of Cospin, Serine Protease Inhibitor Involved in Defense of Coprinopsis cinerea Fruiting Bodies. J.Biol.Chem., 287, 2012
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7ZNX
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![BU of 7znx by Molmil](/molmil-images/mine/7znx) | |
2WKK
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![BU of 2wkk by Molmil](/molmil-images/mine/2wkk) | Identification of the glycan target of the nematotoxic fungal galectin CGL2 in Caenorhabditis elegans | Descriptor: | GALECTIN-2, GLYCEROL, MAGNESIUM ION, ... | Authors: | Butschi, A, Titz, A, Waelti, M, Olieric, V, Paschinger, K, Xiaoqiang, G, Seeberger, P.H, Wilson, I.B.H, Aebi, M, Hengartner, M.O, Kuenzler, M. | Deposit date: | 2009-06-14 | Release date: | 2010-01-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Caenorhabditis Elegans N-Glycan Core Beta-Galactoside Confers Sensitivity Towards Nematotoxic Fungal Galectin Cgl2. Plos Pathog., 6, 2010
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3NBC
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![BU of 3nbc by Molmil](/molmil-images/mine/3nbc) | Clitocybe nebularis ricin B-like lectin (CNL) in complex with lactose, crystallized at pH 4.4 | Descriptor: | Ricin B-like lectin, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Renko, M, Pohleven, J, Sabotic, J, Kos, J, Turk, D. | Deposit date: | 2010-06-03 | Release date: | 2011-09-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.01 Å) | Cite: | Bivalent carbohydrate binding is required for biological activity of Clitocybe nebularis lectin (CNL), the N,N'-diacetyllactosediamine (GalNAc beta 1-4GlcNAc, LacdiNAc)-specific lectin from basidiomycete C. nebularis J.Biol.Chem., 287, 2012
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3NBD
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![BU of 3nbd by Molmil](/molmil-images/mine/3nbd) | Clitocybe nebularis ricin B-like lectin (CNL) in complex with lactose, crystallized at pH 7.1 | Descriptor: | Ricin B-like lectin, SULFATE ION, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Renko, M, Pohleven, J, Sabotic, J, Kos, J, Turk, D. | Deposit date: | 2010-06-03 | Release date: | 2011-09-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | Bivalent carbohydrate binding is required for biological activity of Clitocybe nebularis lectin (CNL), the N,N'-diacetyllactosediamine (GalNAc beta 1-4GlcNAc, LacdiNAc)-specific lectin from basidiomycete C. nebularis J.Biol.Chem., 287, 2012
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3NBE
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![BU of 3nbe by Molmil](/molmil-images/mine/3nbe) | Clitocybe nebularis ricin B-like lectin (CNL) in complex with N,N'-diacetyllactosediamine | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-2-azidoethyl 2-acetamido-2-deoxy-beta-D-glucopyranoside, Ricin B-like lectin, SULFATE ION | Authors: | Renko, M, Pohleven, J, Sabotic, J, Kos, J, Turk, D. | Deposit date: | 2010-06-03 | Release date: | 2011-07-13 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Bivalent carbohydrate binding is required for biological activity of Clitocybe nebularis lectin (CNL), the N,N'-diacetyllactosediamine (GalNAc beta 1-4GlcNAc, LacdiNAc)-specific lectin from basidiomycete C. nebularis J.Biol.Chem., 287, 2012
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6GEW
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![BU of 6gew by Molmil](/molmil-images/mine/6gew) | OphA Y63F-sinefungin complex | Descriptor: | OphA, S-ADENOSYL-L-HOMOCYSTEINE, SINEFUNGIN | Authors: | Song, H, Naismith, J.H. | Deposit date: | 2018-04-27 | Release date: | 2018-09-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A molecular mechanism for the enzymatic methylation of nitrogen atoms within peptide bonds. Sci Adv, 4, 2018
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2MN5
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![BU of 2mn5 by Molmil](/molmil-images/mine/2mn5) | NMR structure of Copsin | Descriptor: | Copsin | Authors: | Hofmann, D, Wider, G, Essig, A, Aebi, M. | Deposit date: | 2014-03-28 | Release date: | 2014-10-29 | Last modified: | 2019-12-25 | Method: | SOLUTION NMR | Cite: | Copsin, a Novel Peptide-based Fungal Antibiotic Interfering with the Peptidoglycan Synthesis. J.Biol.Chem., 289, 2014
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8Q7J
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![BU of 8q7j by Molmil](/molmil-images/mine/8q7j) | Conformations of macrocyclic peptides sampled by exact NOEs: models for cell-permeability | Descriptor: | CYCLOSPORIN A | Authors: | Ruedisser, S.H, Matabaro, E, Sonderegger, L, Guentert, P, Kuenzler, M, Gossert, A.D. | Deposit date: | 2023-08-16 | Release date: | 2023-12-06 | Last modified: | 2024-01-03 | Method: | SOLUTION NMR | Cite: | Conformations of Macrocyclic Peptides Sampled by Nuclear Magnetic Resonance: Models for Cell-Permeability. J.Am.Chem.Soc., 145, 2023
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8QAQ
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![BU of 8qaq by Molmil](/molmil-images/mine/8qaq) | Conformations of macrocyclic peptides sampled by exact NOEs: models for cell-permeability. Conformation 1 of omphalotin A in apolar solvents. | Descriptor: | TRP-MVA-ILE-MVA-MVA-SAR-MVA-IML-SAR-VAL-IML-SAR | Authors: | Ruedisser, S.H, Matabaro, E, Sonderegger, L, Guentert, P, Kuenzler, M, Gossert, A.D. | Deposit date: | 2023-08-23 | Release date: | 2023-12-06 | Last modified: | 2024-01-03 | Method: | SOLUTION NMR | Cite: | Conformations of Macrocyclic Peptides Sampled by Nuclear Magnetic Resonance: Models for Cell-Permeability. J.Am.Chem.Soc., 145, 2023
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8QAS
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![BU of 8qas by Molmil](/molmil-images/mine/8qas) | Conformations of macrocyclic peptides sampled by exact NOEs: models for cell-permeability. NMR structure of Omphalotin A in methanol / water indoleOut conformation. | Descriptor: | TRP-MVA-ILE-MVA-MVA-SAR-MVA-IML-SAR-VAL-IML-SAR | Authors: | Ruedisser, S.H, Matabaro, E, Sonderegger, L, Guentert, P, Kuenzler, M, Gossert, A.D. | Deposit date: | 2023-08-23 | Release date: | 2023-12-06 | Last modified: | 2024-01-03 | Method: | SOLUTION NMR | Cite: | Conformations of Macrocyclic Peptides Sampled by Nuclear Magnetic Resonance: Models for Cell-Permeability. J.Am.Chem.Soc., 145, 2023
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8QBP
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![BU of 8qbp by Molmil](/molmil-images/mine/8qbp) | Conformations of macrocyclic peptides sampled by exact NOEs: models for cell-permeability. NMR structure of Omphalotin A in methanol / water indoleOut conformation. | Descriptor: | TRP-MVA-ILE-MVA-MVA-SAR-MVA-IML-SAR-VAL-IML-SAR | Authors: | Ruedisser, S.H, Matabaro, E, Sonderegger, L, Guentert, P, Kuenzler, M, Gossert, A.D. | Deposit date: | 2023-08-25 | Release date: | 2023-12-13 | Last modified: | 2024-01-03 | Method: | SOLUTION NMR | Cite: | Conformations of Macrocyclic Peptides Sampled by Nuclear Magnetic Resonance: Models for Cell-Permeability. J.Am.Chem.Soc., 145, 2023
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5N0V
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5N0O
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![BU of 5n0o by Molmil](/molmil-images/mine/5n0o) | |
5N0W
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![BU of 5n0w by Molmil](/molmil-images/mine/5n0w) | |