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Crystal structure of D1228V c-MET bound by compound 16
Descriptor:	1-[(1S)-1-[3-(1H-imidazol-4-yl)phenyl]ethyl]-5-(1H-indazol-7-yl)pyrimidine-2,4-dione, Hepatocyte growth factor receptor, IODIDE ION
Authors:	Collie, G.W.
Deposit date:	2023-04-26
Release date:	2023-07-05
Last modified:	2023-09-20
Method:	X-RAY DIFFRACTION (2.206 Å)
Cite:	Discovery and Optimization of the First ATP Competitive Type-III c-MET Inhibitor. J.Med.Chem., 66, 2023

Crystal structure of the kinase domain of human PAK1 in complex with compound 15
Descriptor:	Serine/threonine-protein kinase PAK 1, [2-chloro-5-(hydroxymethyl)phenyl]{5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-1H-pyrrolo[2,3-b]pyridin-3-yl}methanone
Authors:	Ferguson, A.D.
Deposit date:	2014-04-01
Release date:	2014-09-10
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.49 Å)
Cite:	Identification and optimisation of 7-azaindole PAK1 inhibitors with improved potency and kinase selectivity. MEDCHEMCOMM, 2014