6N3C
 
 | | SegB, conformation of TDP-43 low complexity domain segment A | | Descriptor: | TAR DNA-binding protein 43 | | Authors: | Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. | | Deposit date: | 2018-11-14 | | Release date: | 2019-06-26 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structures of four polymorphic TDP-43 amyloid cores.
Nat.Struct.Mol.Biol., 26, 2019
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6N3B
 | | SegA-asym, conformation of TDP-43 low complexity domain segment A asym | | Descriptor: | TAR DNA-binding protein 43 | | Authors: | Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. | | Deposit date: | 2018-11-14 | | Release date: | 2019-06-26 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Cryo-EM structures of four polymorphic TDP-43 amyloid cores.
Nat.Struct.Mol.Biol., 26, 2019
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6C3F
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6C88
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6NK4
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6C3G
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4LCL
 | | Simvastatin Synthase (LOVD), from Aspergillus Terreus, LovD6 mutant (simh6208) | | Descriptor: | ISOPROPYL ALCOHOL, Transesterase | | Authors: | Gao, X, Sawaya, M.R, Yeates, T.O, Tang, Y. | | Deposit date: | 2013-06-21 | | Release date: | 2014-04-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The role of distant mutations and allosteric regulation on LovD active site dynamics.
Nat.Chem.Biol., 10, 2014
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4LCM
 | | Simvastatin Synthase (LOVD), from Aspergillus Terreus, LovD9 mutant (simh9014) | | Descriptor: | Transesterase | | Authors: | Gao, X, Sawaya, M.R, Yeates, T.O, Tang, Y. | | Deposit date: | 2013-06-21 | | Release date: | 2014-04-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.19 Å) | | Cite: | The role of distant mutations and allosteric regulation on LovD active site dynamics.
Nat.Chem.Biol., 10, 2014
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4IVJ
 | | Structure of a 16 nm protein cage designed by fusing symmetric oligomeric domains, triple mutant, I222 form | | Descriptor: | Non-haem bromoperoxidase BPO-A2, Matrix protein 1 | | Authors: | Lai, Y.-T, Sawaya, M.R, Yeates, T.O. | | Deposit date: | 2013-01-23 | | Release date: | 2013-07-24 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (7.351 Å) | | Cite: | Structure and flexibility of nanoscale protein cages designed by symmetric self-assembly.
J.Am.Chem.Soc., 135, 2013
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6ODG
 | | SVQIVY, Crystal Structure of a tau protein fragment | | Descriptor: | Microtubule-associated protein tau | | Authors: | Eisenberg, D.S, Boyer, D.R, Sawaya, M.R, Seidler, P.M. | | Deposit date: | 2019-03-26 | | Release date: | 2019-10-02 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples.
J.Biol.Chem., 294, 2019
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4LFD
 | | Staphylococcus aureus sortase B-substrate complex | | Descriptor: | (CBZ)NPQ(B27) PEPTIDE, SULFATE ION, Sortase B | | Authors: | Jacobitz, A.W, Sawaya, M.R, Yi, S.W, Amer, B.R, Huang, G.L, Nguyen, A.V, Jung, M.E, Clubb, R.T. | | Deposit date: | 2013-06-26 | | Release date: | 2014-02-12 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Structural and Computational Studies of the Staphylococcus aureus Sortase B-Substrate Complex Reveal a Substrate-stabilized Oxyanion Hole.
J.Biol.Chem., 289, 2014
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1OY0
 | | The crystal Structure of the First Enzyme of Pantothenate Biosynthetic Pathway, Ketopantoate Hydroxymethyltransferase from Mycobacterium Tuberculosis Shows a Decameric Assembly and Terminal Helix-Swapping | | Descriptor: | Ketopantoate hydroxymethyltransferase, MAGNESIUM ION | | Authors: | Chaudhuri, B.N, Sawaya, M.R, Kim, C.Y, Waldo, G.S, Park, M.S, Terwilliger, T.C, Yeates, T.O, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2003-04-03 | | Release date: | 2003-07-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The Crystal Structure of the First Enzyme in the Pantothenate Biosynthetic Pathway,
Ketopantoate Hydroxymethyltransferase, from M. tuberculosis
Structure, 11, 2003
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1NBU
 | | 7,8-Dihydroneopterin Aldolase Complexed with Product From Mycobacterium Tuberculosis | | Descriptor: | 2-AMINO-6-HYDROXYMETHYL-7,8-DIHYDRO-3H-PTERIDIN-4-ONE, Probable dihydroneopterin aldolase | | Authors: | Goulding, C.W, Apostol, M.I, Sawaya, M.R, Phillips, M, Parseghian, A, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | | Deposit date: | 2002-12-03 | | Release date: | 2004-01-13 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme.
J.Mol.Biol., 349, 2005
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1P7G
 | | Crystal structure of superoxide dismutase from Pyrobaculum aerophilum | | Descriptor: | ACETATE ION, BETA-MERCAPTOETHANOL, Superoxide dismutase | | Authors: | Lee, S, Sawaya, M.R, Eisenberg, D. | | Deposit date: | 2003-05-01 | | Release date: | 2003-12-02 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of superoxide dismutase from Pyrobaculum aerophilum presents a challenging case in molecular replacement with multiple molecules, pseudo-symmetry and twinning.
Acta Crystallogr.,Sect.D, 59, 2003
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1PK1
 | | Hetero SAM domain structure of Ph and Scm. | | Descriptor: | Polyhomeotic-proximal chromatin protein, Sex comb on midleg CG9495-PA | | Authors: | Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U. | | Deposit date: | 2003-06-04 | | Release date: | 2005-02-15 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer.
J.Biol.Chem., 280, 2005
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1PK3
 | | Scm SAM domain | | Descriptor: | BETA-MERCAPTOETHANOL, Sex comb on midleg CG9495-PA | | Authors: | Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U. | | Deposit date: | 2003-06-04 | | Release date: | 2005-02-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer.
J.Biol.Chem., 280, 2005
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1Q57
 | | The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7 | | Descriptor: | DNA primase/helicase | | Authors: | Toth, E.A, Li, Y, Sawaya, M.R, Cheng, Y, Ellenberger, T. | | Deposit date: | 2003-08-06 | | Release date: | 2003-11-25 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.45 Å) | | Cite: | The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7
Mol.Cell, 12, 2003
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1MZ4
 | | Crystal Structure of Cytochrome c550 from Thermosynechococcus elongatus | | Descriptor: | BICARBONATE ION, GLYCEROL, HEME C, ... | | Authors: | Kerfeld, C.A, Sawaya, M.R, Bottin, H, Tran, K.T, Sugiura, M, Kirilovsky, D, Krogmann, D, Yeates, T.O, Boussac, A. | | Deposit date: | 2002-10-05 | | Release date: | 2003-09-23 | | Last modified: | 2021-03-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and EPR characterization of the soluble form of cytochrome c-550 and of the psbV2 gene product from the cyanobacterium Thermosynechococcus elongatus.
Plant Cell.Physiol., 44, 2003
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2PY8
 | | RbcX | | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CHLORIDE ION, Hypothetical protein rbcX | | Authors: | Tanaka, S, Sawaya, M.R, Kerfeld, C.A, Yeates, T.O. | | Deposit date: | 2007-05-15 | | Release date: | 2007-10-09 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structure of the RuBisCO chaperone RbcX from Synechocystis sp. PCC6803.
Acta Crystallogr.,Sect.D, 63, 2007
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5I55
 | | Crystal Structure of the Virulent PSM-alpha3 Peptide Forming a Cross-alpha amyloid-like Fibril | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, Psm alpha-3 | | Authors: | Landau, M, Moshe, A, Tayeb-Fligelman, E, Sawaya, M.R, Coquelle, N, Colletier, J.-P. | | Deposit date: | 2016-02-14 | | Release date: | 2017-03-01 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | The cytotoxic Staphylococcus aureus PSM alpha 3 reveals a cross-alpha amyloid-like fibril.
Science, 355, 2017
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7MGP
 | | CmcA from Type II Cut MCP | | Descriptor: | BMC domain-containing protein | | Authors: | Ochoa, J.M, Escoto, X, Sawaya, M.R, Yeates, T.O. | | Deposit date: | 2021-04-13 | | Release date: | 2021-09-08 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural characterization of hexameric shell proteins from two types of choline-utilization bacterial microcompartments
Acta Crystallogr.,Sect.F, 77, 2021
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7MPX
 | | CmcC E36G mutant from Type II Cut MCP | | Descriptor: | BMC domain-containing protein, PHOSPHATE ION | | Authors: | Ochoa, J.M, Acosta, A.A, Sawaya, M.R, Yeates, T.O. | | Deposit date: | 2021-05-05 | | Release date: | 2021-09-08 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural characterization of hexameric shell proteins from two types of choline-utilization bacterial microcompartments
Acta Crystallogr.,Sect.F, 77, 2021
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7MPW
 | | CmcB from Type II Cut MCP | | Descriptor: | BMC domain-containing protein | | Authors: | Ochoa, J.M, Marshall, J.D, Sawaya, M.R, Yeates, T.O. | | Deposit date: | 2021-05-05 | | Release date: | 2021-09-08 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (3.001 Å) | | Cite: | Structural characterization of hexameric shell proteins from two types of choline-utilization bacterial microcompartments
Acta Crystallogr.,Sect.F, 77, 2021
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7MPV
 | | CmcC from Type II Cut MCP | | Descriptor: | BMC domain-containing protein | | Authors: | Ochoa, J.M, Mijares, O, Sawaya, M.R, Yeates, T.O. | | Deposit date: | 2021-05-05 | | Release date: | 2021-09-08 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.292 Å) | | Cite: | Structural characterization of hexameric shell proteins from two types of choline-utilization bacterial microcompartments
Acta Crystallogr.,Sect.F, 77, 2021
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7MN4
 | | CmcB E35G mutant from Type II Cut MCP | | Descriptor: | BMC domain-containing protein | | Authors: | Ochoa, J.M, Mijares, O, Sawaya, M.R, Yeates, T.O. | | Deposit date: | 2021-04-30 | | Release date: | 2021-09-08 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural characterization of hexameric shell proteins from two types of choline-utilization bacterial microcompartments
Acta Crystallogr.,Sect.F, 77, 2021
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