2WFH
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![BU of 2wfh by Molmil](/molmil-images/mine/2wfh) | The Human Slit 2 Dimerization Domain D4 | Descriptor: | SLIT HOMOLOG 2 PROTEIN C-PRODUCT, SULFATE ION | Authors: | Seiradake, E, von Philipsborn, A.C, Henry, M, Fritz, M, Lortat-Jacob, H, Jamin, M, Hemrika, W, Bastmeyer, M, Cusack, S, McCarthy, A.A. | Deposit date: | 2009-04-06 | Release date: | 2009-04-21 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure and functional relevance of the Slit2 homodimerization domain. EMBO Rep., 10, 2009
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2XC7
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![BU of 2xc7 by Molmil](/molmil-images/mine/2xc7) | Solution Structure of PHAX-RBD in complex with ssRNA | Descriptor: | 5'-(AP*UP*CP*GP)-3', PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN | Authors: | Mourao, A, Mackereth, C.D, Varrot, A, Cusack, S, Sattler, M. | Deposit date: | 2010-04-18 | Release date: | 2010-04-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure and RNA Recognition by the Snrna and Snorna Transport Factor Phax. RNA, 16, 2010
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2WJY
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![BU of 2wjy by Molmil](/molmil-images/mine/2wjy) | Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 Orthorhombic form | Descriptor: | REGULATOR OF NONSENSE TRANSCRIPTS 1, SULFATE ION, ZINC ION | Authors: | Clerici, M, Mourao, A, Gutsche, I, Gehring, N.H, Hentze, M.W, Kulozik, A, Kadlec, J, Sattler, M, Cusack, S. | Deposit date: | 2009-06-01 | Release date: | 2009-07-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2. Embo J., 28, 2009
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2Y0M
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![BU of 2y0m by Molmil](/molmil-images/mine/2y0m) | CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN DOSAGE COMPENSATION FACTORS MSL1 AND MOF | Descriptor: | ACETYL COENZYME *A, MALE-SPECIFIC LETHAL 1 HOMOLOG, PROBABLE HISTONE ACETYLTRANSFERASE MYST1, ... | Authors: | Kadlec, J, Hallacli, E, Lipp, M, Holz, H, Sanchez Weatherby, J, Cusack, S, Akhtar, A. | Deposit date: | 2010-12-03 | Release date: | 2011-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Basis for Mof and Msl3 Recruitment Into the Dosage Compensation Complex by Msl1. Nat.Struct.Mol.Biol., 18, 2011
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2Y0N
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![BU of 2y0n by Molmil](/molmil-images/mine/2y0n) | CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN DOSAGE COMPENSATION FACTORS MSL1 AND MSL3 | Descriptor: | MALE-SPECIFIC LETHAL 1 HOMOLOG, MALE-SPECIFIC LETHAL 3 HOMOLOG | Authors: | Kadlec, J, Hallacli, E, Lipp, M, Holz, H, Sanchez Weatherby, J, Cusack, S, Akhtar, A. | Deposit date: | 2010-12-04 | Release date: | 2011-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for Mof and Msl3 Recruitment Into the Dosage Compensation Complex by Msl1. Nat.Struct.Mol.Biol., 18, 2011
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2XI5
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![BU of 2xi5 by Molmil](/molmil-images/mine/2xi5) | N-terminal endonuclease domain of La Crosse virus L-protein | Descriptor: | MANGANESE (II) ION, RNA POLYMERASE L | Authors: | Reguera, J, Weber, F, Cusack, S. | Deposit date: | 2010-06-28 | Release date: | 2010-10-06 | Last modified: | 2012-07-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription. Plos Pathog., 6, 2010
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2XI7
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![BU of 2xi7 by Molmil](/molmil-images/mine/2xi7) | N-terminal endonuclease domain of La Crosse virus L-protein | Descriptor: | 2-4-DIOXO-4-PHENYLBUTANOIC ACID, MANGANESE (II) ION, RNA POLYMERASE L | Authors: | Reguera, J, Weber, F, Cusack, S. | Deposit date: | 2010-06-28 | Release date: | 2010-10-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription. Plos Pathog., 6, 2010
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2WFG
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![BU of 2wfg by Molmil](/molmil-images/mine/2wfg) | Structure of the Candida albicans cytosolic leucyl-tRNA synthetase editing domain bound to a benzoxaborole-AMP adduct | Descriptor: | CYTOSOLIC LEUCYL-TRNA SYNTHETASE, [(1S,3S,5R,6R,8R)-6-(6-AMINOPURIN-9-YL)-4'-ETHYLAMINO-3'-FLUORO-SPIRO[2,4,7-TRIOXA-3-BORANUIDABICYCLO[3.3.0]OCTANE-3,7'-8-OXA-7-BORANUIDABICYCLO[4.3.0]NONA-1,3,5-TRIENE]-8-YL]METHYL DIHYDROGEN PHOSPHATE | Authors: | Seiradake, E, Mao, W, Hernandez, V, Baker, S.J, Plattner, J.J, Alley, M.R.K, Cusack, S. | Deposit date: | 2009-04-05 | Release date: | 2009-05-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structures of the Human and Fungal Cytosolic Leucyl-tRNA Synthetase Editing Domains: A Structural Basis for the Rational Design of Antifungal Benzoxaboroles. J.Mol.Biol., 390, 2009
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2WJV
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![BU of 2wjv by Molmil](/molmil-images/mine/2wjv) | Crystal structure of the complex between human nonsense mediated decay factors UPF1 and UPF2 | Descriptor: | REGULATOR OF NONSENSE TRANSCRIPTS 1, REGULATOR OF NONSENSE TRANSCRIPTS 2, SULFATE ION, ... | Authors: | Clerici, M, Mourao, A, Gutsche, I, Gehring, N.H, Hentze, M.W, Kulozik, A, Kadlec, J, Sattler, M, Cusack, S. | Deposit date: | 2009-06-01 | Release date: | 2009-07-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Unusual Bipartite Mode of Interaction between the Nonsense-Mediated Decay Factors, Upf1 and Upf2. Embo J., 28, 2009
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4A2Q
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![BU of 4a2q by Molmil](/molmil-images/mine/4a2q) | Structure of duck RIG-I tandem CARDs and helicase domain | Descriptor: | RETINOIC ACID INDUCIBLE PROTEIN I | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | Deposit date: | 2011-09-28 | Release date: | 2011-10-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA. Cell(Cambridge,Mass.), 147, 2011
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4BHH
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![BU of 4bhh by Molmil](/molmil-images/mine/4bhh) | Crystal structure of tetramer of La Crosse virus nucleoprotein in complex with ssRNA | Descriptor: | NUCLEOPROTEIN, POLY-URIDINE 45-MER | Authors: | Reguera, J, Malet, H, Weber, F, Cusack, S. | Deposit date: | 2013-04-03 | Release date: | 2013-04-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural Basis for Encapsidation of Genomic RNA by La Crosse Orthobunyavirus Nucleoprotein. Proc.Natl.Acad.Sci.USA, 110, 2013
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4A2P
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![BU of 4a2p by Molmil](/molmil-images/mine/4a2p) | Structure of duck RIG-I helicase domain | Descriptor: | RETINOIC ACID INDUCIBLE PROTEIN I | Authors: | Kowalinski, E, Lunardi, T, McCarthy, A.A, Cusack, S. | Deposit date: | 2011-09-28 | Release date: | 2011-10-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA. Cell(Cambridge,Mass.), 147, 2011
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4AQQ
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![BU of 4aqq by Molmil](/molmil-images/mine/4aqq) | Dodecahedron formed of penton base protein from adenovirus Ad3 | Descriptor: | CALCIUM ION, L2 PROTEIN III (PENTON BASE) | Authors: | Burmeister, W.P, Szolajska, E, Zochowska, M, Nerlo, B, Andreev, I, Schoehn, G, Andrieu, J.-P, Fender, P, Naskalska, A, Zubieta, C, Cusack, S, Chroboczek, J. | Deposit date: | 2012-04-19 | Release date: | 2012-10-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (4.75 Å) | Cite: | The Structural Basis for the Integrity of Adenovirus Ad3 Dodecahedron. Plos One, 7, 2012
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4ARI
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![BU of 4ari by Molmil](/molmil-images/mine/4ari) | Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and the benzoxaborole AN2679 in the editing conformation | Descriptor: | GLYCEROL, LEUCINE--TRNA LIGASE, MAGNESIUM ION, ... | Authors: | Palencia, A, Crepin, T, Vu, M.T, Lincecum Jr, T.L, Martinis, S.A, Cusack, S. | Deposit date: | 2012-04-24 | Release date: | 2012-06-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase Nat.Struct.Mol.Biol., 19, 2012
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4AWK
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![BU of 4awk by Molmil](/molmil-images/mine/4awk) | Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with diketo compound 1 | Descriptor: | (2Z)-4-[(3S)-1-(benzylsulfonyl)-3-(4-chlorobenzyl)piperidin-3-yl]-2-hydroxy-4-oxobut-2-enoic acid, MANGANESE (II) ION, POLYMERASE PA | Authors: | Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. | Deposit date: | 2012-06-04 | Release date: | 2012-08-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8, 2012
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4B9X
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![BU of 4b9x by Molmil](/molmil-images/mine/4b9x) | Structure of extended Tudor domain TD3 from mouse TDRD1 | Descriptor: | TUDOR DOMAIN-CONTAINING PROTEIN 1 | Authors: | Mathioudakis, N, Palencia, A, Kadlec, J, Round, A, Tripsianes, K, Sattler, M, Pillai, R.S, Cusack, S. | Deposit date: | 2012-09-08 | Release date: | 2012-10-17 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The Multiple Tudor Domain-Containing Protein Tdrd1 is a Molecular Scaffold for Mouse Piwi Proteins and Pirna Biogenesis Factors. RNA, 18, 2012
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4AWF
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![BU of 4awf by Molmil](/molmil-images/mine/4awf) | Influenza strain pH1N1 2009 polymerase subunit PA endonuclease in complex with 2 4-dioxo-4-phenylbutanoic acid DPBA | Descriptor: | 2-4-DIOXO-4-PHENYLBUTANOIC ACID, MANGANESE (II) ION, POLYMERASE PA | Authors: | Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. | Deposit date: | 2012-06-03 | Release date: | 2012-08-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8, 2012
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4B9W
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![BU of 4b9w by Molmil](/molmil-images/mine/4b9w) | Structure of extended Tudor domain TD3 from mouse TDRD1 in complex with MILI peptide containing dimethylarginine 45. | Descriptor: | GLYCEROL, PIWI-LIKE PROTEIN 2, TUDOR DOMAIN-CONTAINING PROTEIN 1 | Authors: | Mathioudakis, N, Palencia, A, Kadlec, J, Round, A, Tripsianes, K, Sattler, M, Pillai, R.S, Cusack, S. | Deposit date: | 2012-09-08 | Release date: | 2012-10-17 | Last modified: | 2019-04-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The multiple Tudor domain-containing protein TDRD1 is a molecular scaffold for mouse Piwi proteins and piRNA biogenesis factors. Rna, 18, 2012
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4BGP
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![BU of 4bgp by Molmil](/molmil-images/mine/4bgp) | Crystal structure of La Crosse virus nucleoprotein | Descriptor: | GLYCEROL, NUCLEOPROTEIN, SULFATE ION | Authors: | Reguera, J, Malet, H, Weber, F, Cusack, S. | Deposit date: | 2013-03-28 | Release date: | 2013-04-24 | Last modified: | 2013-05-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Basis for Encapsidation of Genomic RNA by La Crosse Orthobunyavirus Nucleoprotein Proc.Natl.Acad.Sci.USA, 110, 2013
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4CEK
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![BU of 4cek by Molmil](/molmil-images/mine/4cek) | Crystal structure of the second MIF4G domain of human nonsense mediated decay factor UPF2 | Descriptor: | REGULATOR OF NONSENSE TRANSCRIPTS 2 | Authors: | Clerici, M, Deniaud, A, Boehm, V, Gehring, N.H, Schaffitzel, C, Cusack, S. | Deposit date: | 2013-11-11 | Release date: | 2013-12-11 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural and Functional Analysis of the Three Mif4G Domains of Nonsense-Mediated Decay Factor Upf2. Nucleic Acids Res., 42, 2014
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4CHC
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![BU of 4chc by Molmil](/molmil-images/mine/4chc) | Crystal structure of the N-terminal domain of the PA subunit of Thogoto virus polymerase (form 2) | Descriptor: | POLYMERASE ACIDIC PROTEIN | Authors: | Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S. | Deposit date: | 2013-12-01 | Release date: | 2014-02-05 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains. Plos One, 9, 2014
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4CHE
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![BU of 4che by Molmil](/molmil-images/mine/4che) | Crystal structure of the putative cap-binding domain of the PB2 subunit of Thogoto virus polymerase | Descriptor: | POLYMERASE BASIC PROTEIN 2 | Authors: | Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S. | Deposit date: | 2013-12-01 | Release date: | 2014-02-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains. Plos One, 9, 2014
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4CGS
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![BU of 4cgs by Molmil](/molmil-images/mine/4cgs) | Crystal structure of the N-terminal domain of the PA subunit of Dhori virus polymerase | Descriptor: | GLYCEROL, POLYMERASE SUBUNIT PA | Authors: | Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S. | Deposit date: | 2013-11-26 | Release date: | 2014-02-05 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains. Plos One, 9, 2014
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4AVQ
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![BU of 4avq by Molmil](/molmil-images/mine/4avq) | Influenza strain pH1N1 2009 polymerase subunit PA endonuclease | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, POLYMERASE PA | Authors: | Kowalinski, E, Zubieta, C, Wolkerstorfer, A, Szolar, O.H, Ruigrok, R.W, Cusack, S. | Deposit date: | 2012-05-29 | Release date: | 2012-08-22 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase. Plos Pathog., 8, 2012
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4B86
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![BU of 4b86 by Molmil](/molmil-images/mine/4b86) | Crystal structure of the MSL1-MSL2 complex (3.5A) | Descriptor: | MALE-SPECIFIC LETHAL 1 HOMOLOG, MALE-SPECIFIC LETHAL 2 HOMOLOG, ZINC ION | Authors: | Hallacli, E, Lipp, M, Georgiev, P, Spielman, C, Cusack, S, Akhtar, A, Kadlec, J. | Deposit date: | 2012-08-24 | Release date: | 2013-02-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Msl1-Mediated Dimerization of the Dosage Compensation Complex is Essential for Male X-Chromosome Regulation in Drosophila. Mol.Cell, 48, 2012
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