9LGM
 
 | | Cryo-EM structure of GPR4 complexed with Gs in pH8.0 | | Descriptor: | G-protein coupled receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2025-01-10 | | Release date: | 2025-04-23 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Structural basis of stepwise proton sensing-mediated GPCR activation.
Cell Res., 35, 2025
|
|
9JFZ
 | | Cryo-EM structure of intermediate state GPR4 complexed with miniGs/q in pH7.5 | | Descriptor: | G-protein coupled receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2024-09-05 | | Release date: | 2025-04-23 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis of stepwise proton sensing-mediated GPCR activation.
Cell Res., 35, 2025
|
|
9JFX
 | | Cryo-EM structure of GPR4 complexed with miniGs/q in pH7.5 | | Descriptor: | G-protein coupled receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2024-09-05 | | Release date: | 2025-04-23 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (2.87 Å) | | Cite: | Structural basis of stepwise proton sensing-mediated GPCR activation.
Cell Res., 35, 2025
|
|
9JFU
 | | Cryo-EM structure of inactive GPR4 with NE52-QQ57 | | Descriptor: | Anti-bril fab light chain, Anti-fab nanobody, G-protein coupled receptor 4,Soluble cytochrome b562, ... | | Authors: | Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2024-09-05 | | Release date: | 2025-04-23 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | Structural basis of stepwise proton sensing-mediated GPCR activation.
Cell Res., 35, 2025
|
|
9JFV
 | | Cryo-EM structure of GPR4 complexed with miniGs/q in pH6.8 | | Descriptor: | G-protein coupled receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2024-09-05 | | Release date: | 2025-04-23 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (2.67 Å) | | Cite: | Structural basis of stepwise proton sensing-mediated GPCR activation.
Cell Res., 35, 2025
|
|
9JHP
 | | Cryo-EM structure of GPR4 complexed with miniG13 in pH6.8 | | Descriptor: | G-protein coupled receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2024-09-10 | | Release date: | 2025-04-23 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Structural basis of stepwise proton sensing-mediated GPCR activation.
Cell Res., 35, 2025
|
|
9JFW
 | | Cryo-EM structure of GPR4 complexed with Gs in pH6.8 | | Descriptor: | G-protein coupled receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2024-09-05 | | Release date: | 2025-04-23 | | Last modified: | 2025-07-02 | | Method: | ELECTRON MICROSCOPY (3.13 Å) | | Cite: | Structural basis of stepwise proton sensing-mediated GPCR activation.
Cell Res., 35, 2025
|
|
8ZCF
 | | Cryo-EM structure of GPR4 complexed with Gs in pH7.5 | | Descriptor: | G-protein coupled receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2024-04-29 | | Release date: | 2025-04-23 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural basis of stepwise proton sensing-mediated GPCR activation.
Cell Res., 35, 2025
|
|
8ZCE
 | | Cryo-EM structure of GPR4 complexed with Gs in pH6.0 | | Descriptor: | G-protein coupled receptor 4, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2024-04-29 | | Release date: | 2025-04-23 | | Last modified: | 2025-06-18 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural basis of stepwise proton sensing-mediated GPCR activation.
Cell Res., 35, 2025
|
|
9UT8
 | | The full-length human sweet taste receptor TAS1R2 and TAS1R3 in the apo state | | Descriptor: | Taste receptor type 1 member 2,Engineered red fluorescent protein mScarlet3, Taste receptor type 1 member 3,mNeonGreen | | Authors: | Shi, Z.J, Xu, W.X, Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2025-05-03 | | Release date: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (3.41 Å) | | Cite: | Structural and functional characterization of human sweet taste receptor.
Nature, 2025
|
|
9UTC
 | | The VFT domains of human sweet taste receptor TAS1R2 and TAS1R3 in the sucralose-bound state | | Descriptor: | 4-chloro-4-deoxy-alpha-D-galactopyranose-(1-2)-1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose, Taste receptor type 1 member 2,Taste receptor type 1 member 2,Engineered red fluorescent protein mScarlet3, Taste receptor type 1 member 3,mNeonGreen | | Authors: | Shi, Z.J, Xu, W.X, Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2025-05-03 | | Release date: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Structural and functional characterization of human sweet taste receptor.
Nature, 2025
|
|
9UT9
 | | The VFT domains of human sweet taste receptor TAS1R2 and TAS1R3 in the apo state | | Descriptor: | Taste receptor type 1 member 2,Engineered red fluorescent protein mScarlet3, Taste receptor type 1 member 3,mNeonGreen | | Authors: | Shi, Z.J, Xu, W.X, Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2025-05-03 | | Release date: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (3.18 Å) | | Cite: | Structural and functional characterization of human sweet taste receptor.
Nature, 2025
|
|
9UTA
 | | The transmembrane domains of human sweet taste receptor TAS1R2 and TAS1R3 in the apo state | | Descriptor: | Taste receptor type 1 member 2,Engineered red fluorescent protein mScarlet3, Taste receptor type 1 member 3,mNeonGreen | | Authors: | Shi, Z.J, Xu, W.X, Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2025-05-03 | | Release date: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (3.77 Å) | | Cite: | Structural and functional characterization of human sweet taste receptor.
Nature, 2025
|
|
9UTB
 | | The full-length human sweet taste receptor TAS1R2 and TAS1R3 in the sucralose-bound state | | Descriptor: | 4-chloro-4-deoxy-alpha-D-galactopyranose-(1-2)-1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose, Taste receptor type 1 member 2,Taste receptor type 1 member 2,Taste receptor type 1 member 2,Engineered red fluorescent protein mScarlet3, Taste receptor type 1 member 3,mNeonGreen | | Authors: | Shi, Z.J, Xu, W.X, Yue, X.L, Wu, L.J, Hua, T, Liu, Z.J. | | Deposit date: | 2025-05-03 | | Release date: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (3.59 Å) | | Cite: | Structural and functional characterization of human sweet taste receptor.
Nature, 2025
|
|
