5INL
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![BU of 5inl by Molmil](/molmil-images/mine/5inl) | Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex with deoxyadenosine | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, DNA (5'-D(P*AP*CP*GP*AP*AP*TP*TP*CP*G)-3'), ... | Authors: | Schellenberg, M.J, Vilas, C.K, Williams, R.S. | Deposit date: | 2016-03-07 | Release date: | 2016-04-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.551 Å) | Cite: | Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2. Nucleic Acids Res., 44, 2016
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6U2O
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![BU of 6u2o by Molmil](/molmil-images/mine/6u2o) | |
6U6B
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![BU of 6u6b by Molmil](/molmil-images/mine/6u6b) | Structure of human DNA polymerase beta misinserting dAMPNPP opposite the 5'G of the cisplatin Pt-GG intrastrand crosslink with Manganese in the active site | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Cisplatin, DNA (5'-D(*CP*CP*CP*AP*CP*GP*GP*CP*CP*CP*AP*TP*CP*AP*CP*C)-3'), ... | Authors: | Ouzon-Shubeita, H, Vilas, C.K, Lee, S. | Deposit date: | 2019-08-29 | Release date: | 2020-09-09 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.108 Å) | Cite: | Structural insights into the promutagenic bypass of the major cisplatin-induced DNA lesion. Biochem.J., 477, 2020
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5HT2
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![BU of 5ht2 by Molmil](/molmil-images/mine/5ht2) | Mouse Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex with 1-N6-etheno-adenine | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, DNA, ... | Authors: | Schellenberg, M.J, Vilas, C.K, Williams, R.S. | Deposit date: | 2016-01-26 | Release date: | 2016-04-27 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2. Nucleic Acids Res., 44, 2016
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5INK
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![BU of 5ink by Molmil](/molmil-images/mine/5ink) | |
5INM
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![BU of 5inm by Molmil](/molmil-images/mine/5inm) | |
5INQ
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![BU of 5inq by Molmil](/molmil-images/mine/5inq) | |
5INP
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![BU of 5inp by Molmil](/molmil-images/mine/5inp) | |
5INO
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![BU of 5ino by Molmil](/molmil-images/mine/5ino) | |
5INN
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![BU of 5inn by Molmil](/molmil-images/mine/5inn) | Mouse Tdp2 D358N protein, apo state with increased disorder amongst variable DNA-binding grasp conformations | Descriptor: | CHLORIDE ION, GLYCEROL, SULFATE ION, ... | Authors: | Schellenberg, M.J, Appel, C.D, Williams, R.S. | Deposit date: | 2016-03-07 | Release date: | 2016-04-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2. Nucleic Acids Res., 44, 2016
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