7DEI
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![BU of 7dei by Molmil](/molmil-images/mine/7dei) | Structure of human ORP3 ORD domain in complex with PI(4)P | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Oxysterol-binding protein-related protein 3 | Authors: | Tong, J, Tan, L, Im, Y.J. | Deposit date: | 2020-11-04 | Release date: | 2021-03-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins. Plos One, 16, 2021
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7DEJ
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![BU of 7dej by Molmil](/molmil-images/mine/7dej) | Structure of human ORP3 ORD in apo-form | Descriptor: | Oxysterol-binding protein-related protein 3 | Authors: | Tong, J, Tan, L, Im, Y.J. | Deposit date: | 2020-11-04 | Release date: | 2021-03-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins. Plos One, 16, 2021
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6IYB
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![BU of 6iyb by Molmil](/molmil-images/mine/6iyb) | Structure of human ORP1 ANK - Rab7 complex | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Oxysterol-binding protein-related protein 1, ... | Authors: | Tong, J, Im, Y.J. | Deposit date: | 2018-12-14 | Release date: | 2019-03-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.091 Å) | Cite: | Structural basis of human ORP1-Rab7 interaction for the late-endosome and lysosome targeting. PLoS ONE, 14, 2019
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5YQQ
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![BU of 5yqq by Molmil](/molmil-images/mine/5yqq) | |
5YQI
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![BU of 5yqi by Molmil](/molmil-images/mine/5yqi) | Crystal structure of the first StARkin domain of Lam2 | Descriptor: | Membrane-anchored lipid-binding protein YSP2 | Authors: | Tong, J, Im, Y.J. | Deposit date: | 2017-11-06 | Release date: | 2018-01-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural basis of sterol recognition and nonvesicular transport by lipid transfer proteins anchored at membrane contact sites Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5YQP
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![BU of 5yqp by Molmil](/molmil-images/mine/5yqp) | Crystal structure of the second StARkin domain of Lam4 | Descriptor: | Membrane-anchored lipid-binding protein LAM4 | Authors: | Tong, J, Manik, K.M, IM, Y.J. | Deposit date: | 2017-11-07 | Release date: | 2018-09-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural basis of sterol recognition and nonvesicular transport by lipid transfer proteins anchored at membrane contact sites Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5YS0
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![BU of 5ys0 by Molmil](/molmil-images/mine/5ys0) | |
5YQR
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![BU of 5yqr by Molmil](/molmil-images/mine/5yqr) | Crystal structure of the PH-like domain of Lam6 | Descriptor: | Endolysin/Membrane-anchored lipid-binding protein LAM6 fusion protein, NONAETHYLENE GLYCOL | Authors: | Tong, J, Im, Y.J. | Deposit date: | 2017-11-07 | Release date: | 2018-01-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.402 Å) | Cite: | Structural basis of sterol recognition and nonvesicular transport by lipid transfer proteins anchored at membrane contact sites Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4IAP
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![BU of 4iap by Molmil](/molmil-images/mine/4iap) | Crystal structure of PH domain of Osh3 from Saccharomyces cerevisiae | Descriptor: | Oxysterol-binding protein homolog 3,Endolysin,Oxysterol-binding protein homolog 3, SULFATE ION | Authors: | Tong, J, Im, Y.J. | Deposit date: | 2012-12-07 | Release date: | 2013-07-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins Structure, 21, 2013
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4INQ
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![BU of 4inq by Molmil](/molmil-images/mine/4inq) | Crystal structure of Osh3 ORD in complex with PI(4)P from Saccharomyces cerevisiae | Descriptor: | (2R)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Oxysterol-binding protein homolog 3 | Authors: | Tong, J, Im, Y.J. | Deposit date: | 2013-01-05 | Release date: | 2013-07-31 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins Structure, 21, 2013
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4IC4
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![BU of 4ic4 by Molmil](/molmil-images/mine/4ic4) | |
6L1M
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![BU of 6l1m by Molmil](/molmil-images/mine/6l1m) | |
4R0Y
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![BU of 4r0y by Molmil](/molmil-images/mine/4r0y) | |
6L1D
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![BU of 6l1d by Molmil](/molmil-images/mine/6l1d) | |
8XSI
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![BU of 8xsi by Molmil](/molmil-images/mine/8xsi) | SARS-CoV-2 RBD + IMCAS-364 (Local Refinement) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IMCAS-364 H chain, IMCAS-364 L chain, ... | Authors: | Tong, Z, Cui, Y, Xie, Y, Tong, J, Gao, G.F, Qi, J. | Deposit date: | 2024-01-09 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.1 Å) | Cite: | Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1. Cell Rep, 43, 2024
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8XSL
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![BU of 8xsl by Molmil](/molmil-images/mine/8xsl) | SARS-CoV-2 spike + IMCAS-123 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IMCAS-123 heavy chain, ... | Authors: | Tong, Z, Cui, Y, Xie, Y, Tong, J, Gao, G.F, Qi, J. | Deposit date: | 2024-01-09 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1. Cell Rep, 43, 2024
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8XSJ
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![BU of 8xsj by Molmil](/molmil-images/mine/8xsj) | SARS-CoV-2 Omicron BA.4 RBD + IMCAS-316 + ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Tong, Z, Cui, Y, Xie, Y, Tong, J, Gao, G.F, Qi, J. | Deposit date: | 2024-01-09 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.61 Å) | Cite: | Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1. Cell Rep, 43, 2024
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8XSE
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![BU of 8xse by Molmil](/molmil-images/mine/8xse) | SARS-CoV-2 RBD + IMCAS-123 + IMCAS-72 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IMCAS-123 H chain, IMCAS-123 L chain, ... | Authors: | Tong, Z, Cui, Y, Xie, Y, Tong, J, Gao, G.F, Qi, J. | Deposit date: | 2024-01-09 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1. Cell Rep, 43, 2024
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8XSF
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![BU of 8xsf by Molmil](/molmil-images/mine/8xsf) | SARS-CoV-2 RBD + IMCAS-364 + hACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, IMCAS-364 H chain, ... | Authors: | Tong, Z, Cui, Y, Xie, Y, Tong, J, Gao, G.F, Qi, J. | Deposit date: | 2024-01-09 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.16 Å) | Cite: | Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1. Cell Rep, 43, 2024
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7F65
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![BU of 7f65 by Molmil](/molmil-images/mine/7f65) | Bacetrial Cocaine Esterase with mutations T172R/G173Q/V116K/S117A/A51L, bound to benzoic acid | Descriptor: | BENZOIC ACID, Cocaine esterase, SULFATE ION | Authors: | Ouyang, P.F, Zhang, Y, Tong, J. | Deposit date: | 2021-06-24 | Release date: | 2021-09-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.202 Å) | Cite: | Computational Design and Crystal Structure of a Highly Efficient Benzoylecgonine Hydrolase. Angew.Chem.Int.Ed.Engl., 60, 2021
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7V5N
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![BU of 7v5n by Molmil](/molmil-images/mine/7v5n) | Crystal structure of Fab fragment of bevacizumab bound to DNA aptamer | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*GP*TP*TP*GP*GP*TP*GP*GP*TP*AP*GP*TP*TP*AP*CP*GP*TP*TP*CP*GP*C)-3'), IMIDAZOLE, ... | Authors: | Hishiki, A, Tong, J, Todoroki, K, Hashimoto, H. | Deposit date: | 2021-08-17 | Release date: | 2022-02-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Development of a DNA aptamer that binds to the complementarity-determining region of therapeutic monoclonal antibody and affinity improvement induced by pH-change for sensitive detection. Biosens.Bioelectron., 203, 2022
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5YQJ
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![BU of 5yqj by Molmil](/molmil-images/mine/5yqj) | Crystal structure of the first StARkin domain of Lam4 | Descriptor: | Membrane-anchored lipid-binding protein LAM4 | Authors: | Im, Y.J, Tong, J.S. | Deposit date: | 2017-11-06 | Release date: | 2018-01-31 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis of sterol recognition and nonvesicular transport by lipid transfer proteins anchored at membrane contact sites Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8DSX
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![BU of 8dsx by Molmil](/molmil-images/mine/8dsx) | |
8Y0Y
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![BU of 8y0y by Molmil](/molmil-images/mine/8y0y) | Cryo-EM structure of the 123-316 scDb/PT-RBD complex | Descriptor: | 123-316 scDb, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Jia, G.W, Tong, Z, Tong, J.Y, Su, Z.M. | Deposit date: | 2024-01-23 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Deciphering a reliable synergistic bispecific strategy of rescuing antibodies for SARS-CoV-2 escape variants, including BA.2.86, EG.5.1, and JN.1. Cell Rep, 43, 2024
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7ZL9
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![BU of 7zl9 by Molmil](/molmil-images/mine/7zl9) | Crystal structure of human GPCR Niacin receptor (HCA2) | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Hydroxycarboxylic acid receptor 2,Soluble cytochrome b562, ... | Authors: | Yang, Y, Kang, H.J, Gao, R.G, Wang, J.J, Han, G.W, FiBerto, J.F, Wu, L.J, Tong, J.H, Qu, L, Wu, Y.R, Pileski, R, Li, X.M, Zhang, X.C, Zhao, S.W, Kenakin, T, Wang, Q, Stevens, R.C, Peng, W, Roth, B.L, Rao, Z.H, Liu, Z.J. | Deposit date: | 2022-04-14 | Release date: | 2023-04-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural insights into the human niacin receptor HCA2-G i signalling complex. Nat Commun, 14, 2023
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