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Crystal structure of the Fab portion of Olokizumab in complex with IL- 6
Descriptor:	INTERLEUKIN-6, OLOKIZUMAB HEAVY CHAIN, FAB PORTION, ...
Authors:	Shaw, S, Bourne, T, Meier, C, Carrington, B, Gelinas, R, Henry, A, Popplewell, A, Adams, R, Baker, T, Rapecki, S, Marshall, D, Neale, H, Lawson, A.
Deposit date:	2014-01-22
Release date:	2014-04-30
Last modified:	2024-10-23
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	Discovery and Characterization of Olokizumab: A Humanized Antibody Targeting Interleukin-6 and Neutralizing Gp130-Signaling. Mabs, 6, 2014

Development of a monoclonal antibody targeting secreted aP2 to treat diabetes and fatty liver disease
Descriptor:	Fab CA33 Heavy chain, Fab CA33 light chain, Fatty acid-binding protein, ...
Authors:	Doyle, C.
Deposit date:	2015-06-12
Release date:	2015-06-24
Last modified:	2024-11-06
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes. Sci Transl Med, 7, 2015

Development of a therapeutic monoclonal antibody targeting secreted aP2 to treat type 2 diabetes.
Descriptor:	Fatty acid-binding protein, adipocyte, HA3 Fab Heavy Chain, ...
Authors:	Doyle, C, Birrane, G.
Deposit date:	2015-08-17
Release date:	2016-01-13
Last modified:	2024-11-06
Method:	X-RAY DIFFRACTION (3 Å)
Cite:	Development of a therapeutic monoclonal antibody that targets secreted fatty acid-binding protein aP2 to treat type 2 diabetes. Sci Transl Med, 7, 2015