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80S rabbit ribosome stalled with benzamide-CHX
Descriptor:	18S rRNA, 28S rRNA, 40S ribosomal protein S21, ...
Authors:	Koga, Y, Hoang, E.M, Park, Y, Keszei, A.F.A, Murray, J, Shao, S, Liau, B.B.
Deposit date:	2021-04-06
Release date:	2021-09-01
Last modified:	2021-09-15
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Discovery of C13-Aminobenzoyl Cycloheximide Derivatives that Potently Inhibit Translation Elongation. J.Am.Chem.Soc., 143, 2021

Crystal structure of human CDK8-Cyclin C in complex with cortistatin A
Descriptor:	CORTISTATIN A, CYCLIN-C, CYCLIN-DEPENDENT KINASE 8, ...
Authors:	Myers, A.G, Shair, M.D.
Deposit date:	2014-02-27
Release date:	2015-09-23
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (2.4 Å)
Cite:	Mediator Kinase Inhibition Further Activates Super-Enhancer- Associated Genes in Aml Nature, 526, 2015

NF-Kappa-B1 Bound with a Covalent Inhibitor
Descriptor:	1-(2-bromo-4-chlorophenyl)-N-{(3S)-1-[(E)-iminomethyl]pyrrolidin-3-yl}methanesulfonamide, Nuclear factor NF-kappa-B p105 subunit
Authors:	Hilbert, B.J.
Deposit date:	2023-08-07
Release date:	2024-04-24
Last modified:	2024-05-22
Method:	X-RAY DIFFRACTION (2.02 Å)
Cite:	DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. Cell, 187, 2024