6G9P
| Structural basis for the inhibition of E. coli PBP2 | Descriptor: | Peptidoglycan D,D-transpeptidase MrdA | Authors: | Ruff, M, Levy, N. | Deposit date: | 2018-04-11 | Release date: | 2019-05-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | Structural Basis for E. coli Penicillin Binding Protein (PBP) 2 Inhibition, a Platform for Drug Design. J.Med.Chem., 62, 2019
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6G9F
| Structural basis for the inhibition of E. coli PBP2 | Descriptor: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Peptidoglycan D,D-transpeptidase MrdA | Authors: | Ruff, M, Levy, N. | Deposit date: | 2018-04-10 | Release date: | 2019-05-22 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural Basis for E. coli Penicillin Binding Protein (PBP) 2 Inhibition, a Platform for Drug Design. J.Med.Chem., 62, 2019
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6G9S
| Structural basis for the inhibition of E. coli PBP2 | Descriptor: | (3~{R},6~{S})-6-(aminomethyl)-4-(1,3-oxazol-5-yl)-3-(sulfooxyamino)-3,6-dihydro-2~{H}-pyridine-1-carboxylic acid, Peptidoglycan D,D-transpeptidase MrdA | Authors: | Ruff, M, Levy, N. | Deposit date: | 2018-04-11 | Release date: | 2019-05-22 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Structural Basis for E. coli Penicillin Binding Protein (PBP) 2 Inhibition, a Platform for Drug Design. J.Med.Chem., 62, 2019
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4LH4
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4LH5
| Dual inhibition of HIV-1 replication by Integrase-LEDGF allosteric inhibitors is predominant at post-integration stage during virus production rather than at integration | Descriptor: | (2S)-tert-butoxy[4-(3,4-dihydro-2H-chromen-6-yl)-2-methylquinolin-3-yl]ethanoic acid, Integrase, MAGNESIUM ION | Authors: | Ruff, M, Levy, N, Eiler, S. | Deposit date: | 2013-06-30 | Release date: | 2013-12-25 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage. Retrovirology, 10, 2013
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7BB9
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7BB8
| Crystal structure of Lugdulysin, a Staphylococcus lugdunensis M30 zinc metallopeptidase | Descriptor: | ACETATE ION, CACODYLATE ION, CALCIUM ION, ... | Authors: | Ruff, M, Prevost, G, Prola, K, Levy, N. | Deposit date: | 2020-12-17 | Release date: | 2022-07-13 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.506 Å) | Cite: | Crystal structure of Staphylococcus lugdunensis protease, Lugdulysin To Be Published
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8OWU
| The crystal structure of the polymorphic toxin PT7(Bc) D37A mutant and its cognate immunity PIM7(Bc) complex | Descriptor: | MAGNESIUM ION, PIM7, Transposase | Authors: | Tzarum, N, Fraenkel, R, Deouell, N, Cahana, I. | Deposit date: | 2023-04-28 | Release date: | 2024-06-19 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Systematic discovery of antibacterial and antifungal bacterial toxins. Nat Microbiol, 9, 2024
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8OWS
| The crystal structure of the polymorphic toxin PT1(Em) H44A mutant and its cognate immunity PIM1(Em) complex | Descriptor: | PIM1, Type IV secretion protein Rhs | Authors: | Tzarum, N, Fraenkel, R, Deouell, N, Cahana, I. | Deposit date: | 2023-04-28 | Release date: | 2024-07-03 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Systematic discovery of antibacterial and antifungal bacterial toxins. Nat Microbiol, 9, 2024
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6T6E
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6T6J
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6T6I
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