3J4T
 
 | | Helical model of TubZ-Bt two-stranded filament | | Descriptor: | FtsZ/tubulin-related protein | | Authors: | Agard, D.A, Montabana, E.A. | | Deposit date: | 2013-10-04 | | Release date: | 2014-02-19 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (10.8 Å) | | Cite: | Bacterial tubulin TubZ-Bt transitions between a two-stranded intermediate and a four-stranded filament upon GTP hydrolysis.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3M7U
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3M7T
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3RB8
 | | Structure of the phage tubulin PhuZ(SeMet)-GDP | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative uncharacterized protein | | Authors: | Agard, D.A, Pogliano, J, Kraemer, J.A, Erb, M.L, Waddling, C.A, Montabana, E.A, Wang, H, Nguyen, K, Pham, S. | | Deposit date: | 2011-03-28 | | Release date: | 2012-07-04 | | Last modified: | 2013-01-23 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A phage tubulin assembles dynamic filaments by an atypical mechanism to center viral DNA within the host cell.
Cell(Cambridge,Mass.), 149, 2012
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3R4V
 | | Structure of the phage tubulin PhuZ-GDP | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative uncharacterized protein | | Authors: | Agard, D.A, Pogliano, J, Kraemer, J.A, Erb, M.L, Waddling, C.A, Montabana, E.A, Wang, H, Nguyen, K, Pham, S. | | Deposit date: | 2011-03-17 | | Release date: | 2012-07-04 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | A phage tubulin assembles dynamic filaments by an atypical mechanism to center viral DNA within the host cell.
Cell(Cambridge,Mass.), 149, 2012
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8LPR
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3LPR
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2ULL
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5LPR
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9LPR
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6XG6
 | | Full-length human mitochondrial Hsp90 (TRAP1) with ADP-BeF3 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Heat shock protein 75 kDa, ... | | Authors: | Liu, Y.X, Wang, F, Agard, D.A. | | Deposit date: | 2020-06-17 | | Release date: | 2020-09-30 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | General and robust covalently linked graphene oxide affinity grids for high-resolution cryo-EM.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5WP9
 | | Structural Basis of Mitochondrial Receptor Binding and Constriction by Dynamin-Related Protein 1 | | Descriptor: | Dynamin-1-like protein, MAGNESIUM ION, Mitochondrial dynamics protein MID49, ... | | Authors: | Kalia, R, Wang, R.Y.R, Yusuf, A, Thomas, P.V, Agard, D.A, Shaw, J.M, Frost, A. | | Deposit date: | 2017-08-03 | | Release date: | 2018-06-20 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (4.22 Å) | | Cite: | Structural basis of mitochondrial receptor binding and constriction by DRP1.
Nature, 558, 2018
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4PRO
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6LPR
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1BOQ
 | | PRO REGION C-TERMINUS: PROTEASE ACTIVE SITE INTERACTIONS ARE CRITICAL IN CATALYZING THE FOLDING OF ALPHA-LYTIC PROTEASE | | Descriptor: | PROTEIN (ALPHA-LYTIC PROTEASE), SULFATE ION | | Authors: | Peters, R.J, Shiau, A.K, Sohl, J.L, Anderson, D.E, Tang, G, Silen, J.L, Agard, D.A. | | Deposit date: | 1998-08-05 | | Release date: | 1998-08-12 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Pro region C-terminus:protease active site interactions are critical in catalyzing the folding of alpha-lytic protease.
Biochemistry, 37, 1998
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8FNE
 | | phiPA3 PhuN Tetramer, p2 | | Descriptor: | Maltose/maltodextrin-binding periplasmic protein, PhuN | | Authors: | Nieweglowska, E.S, Brilot, A.F, Mendez-Moran, M, Kokontis, C, Baek, M, Li, J, Cheng, Y, Baker, D, Bondy-Denomy, J, Agard, D.A. | | Deposit date: | 2022-12-27 | | Release date: | 2023-03-01 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | The phi PA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice.
Nat Commun, 14, 2023
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8FV5
 | | Representation of 16-mer phiPA3 PhuN Lattice, p2 | | Descriptor: | Maltose/maltodextrin-binding periplasmic protein, phiPA3 PhuN | | Authors: | Nieweglowska, E.S, Brilot, A.F, Mendez-Moran, M, Kokontis, C, Baek, M, Li, J, Cheng, Y, Baker, D, Bondy-Denomy, J, Agard, D.A. | | Deposit date: | 2023-01-18 | | Release date: | 2023-03-01 | | Last modified: | 2024-05-01 | | Method: | ELECTRON MICROSCOPY (4.21 Å) | | Cite: | The phi PA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice.
Nat Commun, 14, 2023
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8FFW
 | | Cryo-EM structure of the GR-Hsp90-FKBP51 complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... | | Authors: | Noddings, C.M, Agard, D.A. | | Deposit date: | 2022-12-10 | | Release date: | 2023-11-01 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor.
Nat.Struct.Mol.Biol., 30, 2023
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8FFV
 | | Cryo-EM structure of the GR-Hsp90-FKBP52 complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DEXAMETHASONE, Glucocorticoid receptor, ... | | Authors: | Noddings, C.M, Agard, D.A. | | Deposit date: | 2022-12-10 | | Release date: | 2023-11-01 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Cryo-EM reveals how Hsp90 and FKBP immunophilins co-regulate the glucocorticoid receptor.
Nat.Struct.Mol.Biol., 30, 2023
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8GAE
 | | Hsp90 provides platform for CRaf dephosphorylation by PP5 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ... | | Authors: | Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A. | | Deposit date: | 2023-02-22 | | Release date: | 2023-04-26 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Hsp90 provides a platform for kinase dephosphorylation by PP5.
Nat Commun, 14, 2023
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8GFT
 | | Hsp90 provides platform for CRaf dephosphorylation by PP5 | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein HSP 90-beta, ... | | Authors: | Jaime-Garza, M, Nowotny, C.A, Coutandin, D, Wang, F, Tabios, M, Agard, D.A. | | Deposit date: | 2023-03-08 | | Release date: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Hsp90 provides a platform for kinase dephosphorylation by PP5.
Nat Commun, 14, 2023
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3J9I
 | | Thermoplasma acidophilum 20S proteasome | | Descriptor: | Proteasome subunit alpha, Proteasome subunit beta | | Authors: | Li, X, Mooney, P, Zheng, S, Booth, C, Braunfeld, M.B, Gubbens, S, Agard, D.A, Cheng, Y. | | Deposit date: | 2015-02-02 | | Release date: | 2015-02-18 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.
Nat.Methods, 10, 2013
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3J4S
 | | Helical Model of TubZ-Bt four-stranded filament | | Descriptor: | FtsZ/tubulin-related protein, GUANOSINE-5'-DIPHOSPHATE | | Authors: | Montabana, E.A, Agard, D.A. | | Deposit date: | 2013-10-03 | | Release date: | 2014-02-19 | | Last modified: | 2024-02-28 | | Method: | ELECTRON MICROSCOPY (6.8 Å) | | Cite: | Bacterial tubulin TubZ-Bt transitions between a two-stranded intermediate and a four-stranded filament upon GTP hydrolysis.
Proc.Natl.Acad.Sci.USA, 111, 2014
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1TAL
 | | ALPHA-LYTIC PROTEASE AT 120 K (SINGLE STRUCTURE MODEL) | | Descriptor: | ALPHA-LYTIC PROTEASE, SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE | | Authors: | Rader, S.D, Agard, D.A. | | Deposit date: | 1996-10-30 | | Release date: | 1997-04-01 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Conformational substates in enzyme mechanism: the 120 K structure of alpha-lytic protease at 1.5 A resolution.
Protein Sci., 6, 1997
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2LPR
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