1WJ0
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1WIJ
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![BU of 1wij by Molmil](/molmil-images/mine/1wij) | Solution Structure of the DNA-Binding Domain of Ethylene-Insensitive3-Like3 | Descriptor: | ETHYLENE-INSENSITIVE3-like 3 protein | Authors: | Yamasaki, K, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-28 | Release date: | 2004-11-28 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the major DNA-binding domain of Arabidopsis thaliana ethylene-insensitive3-like3. J.Mol.Biol., 348, 2005
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1WMG
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![BU of 1wmg by Molmil](/molmil-images/mine/1wmg) | Crystal structure of the UNC5H2 death domain | Descriptor: | SULFATE ION, SULFITE ION, netrin receptor Unc5h2 | Authors: | Handa, N, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-07-09 | Release date: | 2005-01-09 | Last modified: | 2011-11-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the UNC5H2 death domain ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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5GHT
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![BU of 5ght by Molmil](/molmil-images/mine/5ght) | DNA replication protein | Descriptor: | SsDNA-specific exonuclease | Authors: | Oyama, T. | Deposit date: | 2016-06-20 | Release date: | 2016-10-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.795 Å) | Cite: | Atomic structure of an archaeal GAN suggests its dual roles as an exonuclease in DNA repair and a CMG component in DNA replication. Nucleic Acids Res., 44, 2016
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4YT1
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![BU of 4yt1 by Molmil](/molmil-images/mine/4yt1) | Human PPAR Gamma Ligand Binding Domain in complex with a Gammma Selective Synthetic Partial Agonist MEKT76 | Descriptor: | N-(benzylsulfonyl)-4-propoxy-3-({[4-(pyrimidin-2-yl)benzoyl]amino}methyl)benzamide, Peroxisome proliferator-activated receptor gamma | Authors: | Oyama, T, Ohashi, M, Miyachi, H, Kusunoki, M. | Deposit date: | 2015-03-17 | Release date: | 2016-03-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Peroxisome proliferator-activated receptor gamma (PPAR gamma ) has multiple binding points that accommodate ligands in various conformations: Structurally similar PPAR gamma partial agonists bind to PPAR gamma LBD in different conformations Bioorg.Med.Chem.Lett., 25, 2015
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4ZIP
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![BU of 4zip by Molmil](/molmil-images/mine/4zip) | HIV-1 wild Type protease with GRL-0648A (a isophthalamide-derived P2-Ligand) | Descriptor: | CHLORIDE ION, GLYCEROL, N-[(2,5-dimethyl-1,3-oxazol-4-yl)methyl]-N'-[(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]-N,5-dimethylbenzene-1,3-dicarboxamide, ... | Authors: | Wang, Y.-F, Agniswamy, J, Weber, I.T. | Deposit date: | 2015-04-28 | Release date: | 2015-07-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.11 Å) | Cite: | Structure-based design, synthesis, X-ray studies, and biological evaluation of novel HIV-1 protease inhibitors containing isophthalamide-derived P2-ligands. Bioorg.Med.Chem.Lett., 25, 2015
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5GHS
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![BU of 5ghs by Molmil](/molmil-images/mine/5ghs) | DNA replication protein | Descriptor: | Putative uncharacterized protein, SULFATE ION, SsDNA-specific exonuclease | Authors: | Oyama, T. | Deposit date: | 2016-06-20 | Release date: | 2016-10-12 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.591 Å) | Cite: | Atomic structure of an archaeal GAN suggests its dual roles as an exonuclease in DNA repair and a CMG component in DNA replication. Nucleic Acids Res., 44, 2016
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5GHR
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![BU of 5ghr by Molmil](/molmil-images/mine/5ghr) | DNA replication protein | Descriptor: | Putative uncharacterized protein, SULFATE ION, SsDNA-specific exonuclease | Authors: | Oyama, T. | Deposit date: | 2016-06-20 | Release date: | 2016-10-12 | Last modified: | 2017-12-06 | Method: | X-RAY DIFFRACTION (2.509 Å) | Cite: | Atomic structure of an archaeal GAN suggests its dual roles as an exonuclease in DNA repair and a CMG component in DNA replication. Nucleic Acids Res., 44, 2016
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2COM
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![BU of 2com by Molmil](/molmil-images/mine/2com) | The solution structure of the SWIRM domain of human LSD1 | Descriptor: | Lysine-specific histone demethylase 1 | Authors: | Tochio, N, Umehara, T, Koshiba, S, Inoue, M, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-18 | Release date: | 2005-11-18 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the SWIRM domain of human histone demethylase LSD1 Structure, 14, 2006
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1X4S
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![BU of 1x4s by Molmil](/molmil-images/mine/1x4s) | Solution structure of zinc finger HIT domain in protein FON | Descriptor: | ZINC ION, Zinc finger HIT domain containing protein 2 | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-14 | Release date: | 2005-11-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the zinc finger HIT domain in protein FON Protein Sci., 16, 2007
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1WWQ
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![BU of 1wwq by Molmil](/molmil-images/mine/1wwq) | Solution Structure of Mouse ER | Descriptor: | Enhancer of rudimentary homolog | Authors: | Li, H, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-01-12 | Release date: | 2006-01-03 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the mouse enhancer of rudimentary protein reveals a novel fold J.Biomol.Nmr, 32, 2005
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7OTT
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1UL7
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![BU of 1ul7 by Molmil](/molmil-images/mine/1ul7) | Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3 | Descriptor: | MAP/microtubule affinity-regulating kinase 3 | Authors: | Tochio, N, Koshiba, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-09-10 | Release date: | 2004-03-10 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of the kinase-associated domain 1 of mouse microtubule-associated protein/microtubule affinity-regulating kinase 3 Protein Sci., 15, 2006
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4I8Z
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![BU of 4i8z by Molmil](/molmil-images/mine/4i8z) | Crystal structure of wild type HIV-1 protease in complex with non-peptidic inhibitor, GRL008 | Descriptor: | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-carbamoylphenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate, Protease | Authors: | Yedidi, R.S, Palmer, I, Das, D, Wingfield, P.T, Ghosh, A.K, Mitsuya, H. | Deposit date: | 2012-12-04 | Release date: | 2013-07-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | P2' benzene carboxylic acid moiety is associated with decrease in cellular uptake: evaluation of novel non-peptidic HIV-1 protease inhibitors containing P2 bis-tetrahydrofuran moiety. Antimicrob.Agents Chemother., 57, 2013
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2CU7
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![BU of 2cu7 by Molmil](/molmil-images/mine/2cu7) | Solution structure of the SANT domain of human KIAA1915 protein | Descriptor: | KIAA1915 protein | Authors: | Yoneyama, M, Umehara, T, Saito, K, Tochio, N, Koshiba, S, Inoue, M, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-25 | Release date: | 2005-11-25 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural and Functional Differences of SWIRM Domain Subtypes J.Mol.Biol., 369, 2007
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2CUJ
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![BU of 2cuj by Molmil](/molmil-images/mine/2cuj) | Solution structure of SWIRM domain of mouse transcriptional adaptor 2-like | Descriptor: | transcriptional adaptor 2-like | Authors: | Yoneyama, M, Umehara, T, Sato, M, Tochio, N, Koshiba, S, Inoue, M, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-26 | Release date: | 2005-11-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural and Functional Differences of SWIRM Domain Subtypes J.Mol.Biol., 369, 2007
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2DCE
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![BU of 2dce by Molmil](/molmil-images/mine/2dce) | Solution structure of the SWIRM domain of human KIAA1915 protein | Descriptor: | KIAA1915 protein | Authors: | Yoneyama, M, Tochio, N, Umehara, T, Koshiba, S, Inoue, M, Tanaka, A, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-01-06 | Release date: | 2006-07-06 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural and Functional Differences of SWIRM Domain Subtypes J.Mol.Biol., 369, 2007
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2DCQ
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2DCP
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2E5S
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![BU of 2e5s by Molmil](/molmil-images/mine/2e5s) | Solution structure of the zf-CCCHx2 domain of muscleblind-like 2, isoform 1 [Homo sapiens] | Descriptor: | OTTHUMP00000018578, ZINC ION | Authors: | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-12-22 | Release date: | 2007-06-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the RNA binding domain in the human muscleblind-like protein 2 Protein Sci., 18, 2009
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6KLF
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5JG1
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![BU of 5jg1 by Molmil](/molmil-images/mine/5jg1) | HIV-1 wild Type protease with GRL-031-14A (a Adamantane P1-Ligand with tetrahydropyrano-tetrahydrofuran in P2 and isobutylamine in P1') | Descriptor: | (3R,3aS,7aR)-hexahydro-4H-furo[2,3-b]pyran-3-yl {(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}-1-[(3R,5R,7R)-tricyclo[3.3.1.1~3,7~]decan-1-yl]butan-2-yl}carbamate, CHLORIDE ION, GLYCEROL, ... | Authors: | Wang, Y.-F, Agniswamy, J, Weber, I.T. | Deposit date: | 2016-04-19 | Release date: | 2016-09-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.16 Å) | Cite: | Probing Lipophilic Adamantyl Group as the P1-Ligand for HIV-1 Protease Inhibitors: Design, Synthesis, Protein X-ray Structural Studies, and Biological Evaluation. J.Med.Chem., 59, 2016
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2E61
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![BU of 2e61 by Molmil](/molmil-images/mine/2e61) | Solution structure of the zf-CW domain in zinc finger CW-type PWWP domain protein 1 | Descriptor: | ZINC ION, Zinc finger CW-type PWWP domain protein 1 | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-12-25 | Release date: | 2007-06-26 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural insight into the zinc finger CW domain as a histone modification reader Structure, 18, 2010
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7COV
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![BU of 7cov by Molmil](/molmil-images/mine/7cov) | Potato D-enzyme, native (substrate free) | Descriptor: | 4-alpha-glucanotransferase, chloroplastic/amyloplastic, CALCIUM ION, ... | Authors: | Unno, H, Imamura, K. | Deposit date: | 2020-08-05 | Release date: | 2020-08-26 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural analysis and reaction mechanism of the disproportionating enzyme (D-enzyme) from potato. Protein Sci., 29, 2020
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4NJU
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![BU of 4nju by Molmil](/molmil-images/mine/4nju) | Crystal structure of multidrug-resistant clinical isolate A02 HIV-1 protease in complex with tipranavir | Descriptor: | N-(3-{(1R)-1-[(6R)-4-HYDROXY-2-OXO-6-PHENETHYL-6-PROPYL-5,6-DIHYDRO-2H-PYRAN-3-YL]PROPYL}PHENYL)-5-(TRIFLUOROMETHYL)-2-PYRIDINESULFONAMIDE, Protease | Authors: | Yedidi, R.S, Garimella, H, Kaufman, J.D, Das, D, Wingfield, P.T, Mitsuya, H. | Deposit date: | 2013-11-11 | Release date: | 2014-04-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Conserved Hydrogen-Bonding Network of P2 bis-Tetrahydrofuran-Containing HIV-1 Protease Inhibitors (PIs) with a Protease Active-Site Amino Acid Backbone Aids in Their Activity against PI-Resistant HIV. Antimicrob.Agents Chemother., 58, 2014
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