Search by PDB author

Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM846
Descriptor:	3-{2-[3-({2,4-diamino-6-[4-(trifluoromethyl)phenyl]pyrimidin-5-yl}oxy)propoxy]phenyl}propanoic acid, Dihydrofolate reductase, IMIDAZOLE, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-11-21
Release date:	2023-12-13
Method:	X-RAY DIFFRACTION (1.32 Å)
Cite:	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM846 To be published

8F82

Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM845
Descriptor:	(4S)-2-METHYL-2,4-PENTANEDIOL, 3-{2-[3-({(6M)-2,4-diamino-6-[3-(trifluoromethyl)phenyl]pyrimidin-5-yl}oxy)propoxy]phenyl}propanoic acid, BROMIDE ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-11-21
Release date:	2023-12-13
Method:	X-RAY DIFFRACTION (1.2 Å)
Cite:	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM845 To be published

8F80

Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM738
Descriptor:	1,2-ETHANEDIOL, 3-[2-(3-{[2,4-diamino-6-(4-methoxyphenyl)pyrimidin-5-yl]oxy}propoxy)phenyl]propanoic acid, Dihydrofolate reductase, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-11-21
Release date:	2023-12-13
Method:	X-RAY DIFFRACTION (1.1 Å)
Cite:	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM738 To be published

8F84

Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM787
Descriptor:	3-[2-(3-{[2,4-diamino-6-(4-hydroxybutyl)pyrimidin-5-yl]oxy}propoxy)phenyl]propanoic acid, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-11-21
Release date:	2023-12-13
Method:	X-RAY DIFFRACTION (1.1 Å)
Cite:	Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM787 To be published

8FI6

Crystal Structure of Glycylpeptide N-tetradecanoyltransferase (N-myristoyl transferase) (NMT) from Leishmania major Friedlin bound to tetradecanoyl-CoA (Orthorhombic P Form 3)
Descriptor:	Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-12-15
Release date:	2022-12-28
Last modified:	2023-11-22
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Crystal Structure of Glycylpeptide N-tetradecanoyltransferase (N-myristoyl transferase) (NMT) from Leishmania major Friedlin bound to tetradecanoyl-CoA (Orthorhombic P Form 3) To be published

8FI4

Crystal Structure of Glycylpeptide N-tetradecanoyltransferase (N-myristoyl transferase) (NMT) from Leishmania major Friedlin bound to tetradecanoyl-CoA (Orthorhombic P Form 1)
Descriptor:	Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-12-15
Release date:	2022-12-28
Last modified:	2023-11-22
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Crystal Structure of Glycylpeptide N-tetradecanoyltransferase (N-myristoyl transferase) (NMT) from Leishmania major Friedlin bound to tetradecanoyl-CoA (Orthorhombic P Form 1) To be published

8FI5

Crystal Structure of Glycylpeptide N-tetradecanoyltransferase (N-myristoyl transferase) (NMT) from Leishmania major Friedlin bound to tetradecanoyl-CoA (Orthorhombic P Form 2)
Descriptor:	Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-12-15
Release date:	2022-12-28
Last modified:	2023-11-22
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Crystal Structure of Glycylpeptide N-tetradecanoyltransferase (N-myristoyl transferase) (NMT) from Leishmania major Friedlin bound to tetradecanoyl-CoA (Orthorhombic P Form 2) To be published

8G0V

Crystal Structure of Acetyl-CoA synthetase in complex with a propyne ester AMP inhibitor from Cryptococcus neoformans H99
Descriptor:	1,2-ETHANEDIOL, 5'-O-{(S)-hydroxy[(prop-2-yn-1-yl)oxy]phosphoryl}adenosine, Acetyl-coenzyme A synthetase, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2023-02-01
Release date:	2023-02-15
Last modified:	2024-05-22
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Crystal Structure of Acetyl-CoA synthetase in complex with a propyne ester AMP inhibitor from Cryptococcus neoformans H99 To be published

8G0R

Crystal Structure of Acetyl-CoA synthetase in complex with a cyclopentyl ester AMP inhibitor from Cryptococcus neoformans H99
Descriptor:	5'-O-[(S)-(cyclopentyloxy)(hydroxy)phosphoryl]adenosine, Acetyl-coenzyme A synthetase
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2023-02-01
Release date:	2023-02-15
Last modified:	2024-05-22
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Crystal Structure of Acetyl-CoA synthetase in complex with a cyclopentyl ester AMP inhibitor from Cryptococcus neoformans H99 To be published

8G0U

Crystal Structure of Acetyl-CoA synthetase in complex with an isopropyl ester AMP inhibitor from Cryptococcus neoformans H99
Descriptor:	1,2-ETHANEDIOL, 5'-O-{(R)-hydroxy[(propan-2-yl)oxy]phosphoryl}adenosine, Acetyl-coenzyme A synthetase
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2023-02-01
Release date:	2023-02-15
Last modified:	2024-05-22
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Crystal Structure of Acetyl-CoA synthetase in complex with an isopropyl ester AMP inhibitor from Cryptococcus neoformans H99 To be published

8G0T

Crystal Structure of Acetyl-CoA synthetase in complex with a cyclopropyl ester AMP inhibitor from Cryptococcus neoformans H99
Descriptor:	1,2-ETHANEDIOL, 5'-O-[(R)-(cyclopropyloxy)(hydroxy)phosphoryl]adenosine, Acetyl-coenzyme A synthetase
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2023-02-01
Release date:	2023-02-15
Last modified:	2024-05-22
Method:	X-RAY DIFFRACTION (2.45 Å)
Cite:	Crystal Structure of Acetyl-CoA synthetase in complex with a cyclopropyl ester AMP inhibitor from Cryptococcus neoformans H99 To be published

8G0S

Crystal Structure of Acetyl-CoA synthetase in complex with a cyclopentyl ester AMP inhibitor from Cryptococcus neoformans H99 (tetragonal form)
Descriptor:	5'-O-[(S)-(cyclopentyloxy)(hydroxy)phosphoryl]adenosine, Acetyl-coenzyme A synthetase, CHLORIDE ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2023-02-01
Release date:	2023-02-15
Last modified:	2024-05-22
Method:	X-RAY DIFFRACTION (2.9 Å)
Cite:	Crystal Structure of Acetyl-CoA synthetase in complex with a cyclopentyl ester AMP inhibitor from Cryptococcus neoformans H99 (tetragonal form) To Be Published

4EFI

Crystal Structure of 3-oxoacyl-(Acyl-carrier protein) Synthase from Burkholderia Xenovorans LB400
Descriptor:	3-oxoacyl-(Acyl-carrier protein) synthase, CHLORIDE ION, FORMIC ACID, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease, Craig, T.K, Abendroth, J, Staker, B, Stewart, L, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-03-29
Release date:	2012-04-11
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (1.35 Å)
Cite:	Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013

3IKF

Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with FOL fragment 717, imidazo[2,,1-b][1,3]thiazol-6-ylmethanol
Descriptor:	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ACETATE ION, CHLORIDE ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2009-08-05
Release date:	2009-08-18
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.07 Å)
Cite:	Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011

3JVH

Crystal structure of 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with FOL fragment 8395
Descriptor:	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 5-[(pyridin-3-ylmethyl)amino]-1H-pyrazole-4-carboxamide, GLYCEROL, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2009-09-16
Release date:	2009-09-29
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.69 Å)
Cite:	Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011

6AUB

CRYSTAL STRUCTURE OF BRUTON'S TYROSINE KINASE IN COMPLEX WITH INHIBITOR CGI2815
Descriptor:	4-tert-butyl-N-[2-methyl-3-(1-methyl-5-{[5-(morpholine-4-carbonyl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridin-3-yl)phenyl]benzamide, SULFATE ION, Tyrosine-protein kinase BTK
Authors:	Davies, D.R, Staker, B.L.
Deposit date:	2017-08-31
Release date:	2018-09-12
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.65 Å)
Cite:	To Be Determined TO BE PUBLISHED

6AUA

CRYSTAL STRUCTURE OF BRUTON'S TYROSINE KINASE IN COMPLEX WITH INHIBITOR CGI2625
Descriptor:	GLYCEROL, N-{3-[(2R)-6-{[3-amino-4-(morpholine-4-carbonyl)phenyl]amino}-5-oxo-2,5-dihydropyrazin-2-yl]-2-methylphenyl}-4-(piperidin-1-yl)benzamide, SULFATE ION, ...
Authors:	Davies, D.R, Staker, B.L.
Deposit date:	2017-08-31
Release date:	2018-09-12
Last modified:	2023-10-04
Method:	X-RAY DIFFRACTION (1.66 Å)
Cite:	To Be Determined TO BE PUBLISHED

4FK8

Crystal structure of FERREDOXIN-NADP REDUCTASE from burkholderia thailandensis E264 with bound FAD
Descriptor:	FLAVIN-ADENINE DINUCLEOTIDE, Ferredoxin--NADP reductase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-06-12
Release date:	2012-06-20
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013

4FZI

Crystal structure of prostaglandin F synthase from Trypanosoma cruzi
Descriptor:	GLUTAMIC ACID, Prostaglandin F synthase, SULFATE ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-07-06
Release date:	2012-07-18
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP. Acta Crystallogr F Struct Biol Commun, 71, 2015

4FRY

The structure of a putative signal-transduction protein with CBS domains from Burkholderia ambifaria MC40-6
Descriptor:	ADENOSINE MONOPHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative signal-transduction protein with CBS domains
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-06-26
Release date:	2012-07-11
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013

4G1K

Crystal structure of triosephosphate isomerase from Burkholderia thailandensis
Descriptor:	1,2-ETHANEDIOL, ACETATE ION, SODIUM ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-07-10
Release date:	2012-07-25
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (2.35 Å)
Cite:	Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013

4G5D

X-ray crystal structure of Prostaglandin f synthase from Leishmania major Friedlin bound to NADPH
Descriptor:	NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Prostaglandin f2-alpha synthase/D-arabinose dehydrogenase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-07-17
Release date:	2012-08-15
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP. Acta Crystallogr F Struct Biol Commun, 71, 2015

4G67

Crystal structure of a COG1565 superfamily member and likely methyl transferase from Burkholderia thailandensis bound to S-adenosyl-homocysteine
Descriptor:	1,2-ETHANEDIOL, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-07-18
Release date:	2012-08-01
Last modified:	2024-02-28
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013

3EOM

2.4 A crystal structure of native glutaryl-coa dehydrogenase from Burkholderia pseudomallei
Descriptor:	Glutaryl-CoA dehydrogenase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2008-09-28
Release date:	2008-10-21
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.398 Å)
Cite:	Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening. Acta Crystallogr.,Sect.F, 67, 2011

4FUR

Crystal Structure of Urease subunit gamma 2 from Brucella melitensis biovar Abortus 2308
Descriptor:	1,2-ETHANEDIOL, CHLORIDE ION, Urease subunit gamma 2
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-06-28
Release date:	2012-08-15
Last modified:	2023-09-13
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Crystal Structure of Urease subunit gamma 2 from Brucella melitensis biovar Abortus 2308 TO BE PUBLISHED

<1 2 3 4 5 678 9 10 11 12 13 14 15 16 >

Total results:	451
Displayed results:	25
Sorted by:	Hit score (from highest)