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Cryo-EM structure of CorA in complex with conformation-specific synthetic antibody C12 and 20 mM MgCl2, State MG20-2
Descriptor:	Cobalt/magnesium transport protein CorA, MAGNESIUM ION, sAB C12 Heavy Chain, ...
Authors:	Erramilli, S.K, Perozo, E, Kossiakoff, A.A.
Deposit date:	2023-07-29
Release date:	2025-02-12
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Structural basis for CorA channel gating using conformation-specific synthetic antibodies To Be Published

8TMF

Cryo-EM structure of CorA in complex with conformation-specific synthetic antibody C18 and 100 uM MgCl2, State MG0.1-1C
Descriptor:	Cobalt/magnesium transport protein CorA, MAGNESIUM ION, sAB C18 Heavy Chain, ...
Authors:	Erramilli, S.K, Perozo, E, Kossiakoff, A.A.
Deposit date:	2023-07-29
Release date:	2025-02-12
Method:	ELECTRON MICROSCOPY (3.4 Å)
Cite:	Structural basis for CorA channel gating using conformation-specific synthetic antibodies To Be Published

8TMH

Cryo-EM structure of CorA in complex with conformation-specific synthetic antibody C18 and 100 uM MgCl2, State MG0.1-2B
Descriptor:	Cobalt/magnesium transport protein CorA, MAGNESIUM ION, sAB C18 Heavy Chain, ...
Authors:	Erramilli, S.K, Perozo, E, Kossiakoff, A.A.
Deposit date:	2023-07-29
Release date:	2025-02-12
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Structural basis for CorA channel gating using conformation-specific synthetic antibodies To Be Published

8TMP

Cryo-EM structure of magnesium depleted CorA in complex with conformation-specific synthetic antibody C18, State MGD-1B
Descriptor:	Cobalt/magnesium transport protein CorA, MAGNESIUM ION, sAB C18 Heavy Chain, ...
Authors:	Erramilli, S.K, Perozo, E, Kossiakoff, A.A.
Deposit date:	2023-07-29
Release date:	2025-02-12
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Structural basis for CorA channel gating using conformation-specific synthetic antibodies To Be Published

8TMI

Cryo-EM structure of CorA in complex with conformation-specific synthetic antibody C18 and 100 uM MgCl2, State MG0.1-2C
Descriptor:	Cobalt/magnesium transport protein CorA, MAGNESIUM ION, sAB C18 Heavy Chain, ...
Authors:	Erramilli, S.K, Perozo, E, Kossiakoff, A.A.
Deposit date:	2023-07-29
Release date:	2025-02-12
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Structural basis for CorA channel gating using conformation-specific synthetic antibodies To Be Published

8TMJ

Cryo-EM structure of CorA in complex with conformation-specific synthetic antibody C18 and 100 uM MgCl2, State MG0.1-2D
Descriptor:	Cobalt/magnesium transport protein CorA, MAGNESIUM ION, sAB C18 Heavy Chain, ...
Authors:	Erramilli, S.K, Perozo, E, Kossiakoff, A.A.
Deposit date:	2023-07-29
Release date:	2025-02-12
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Structural basis for CorA channel gating using conformation-specific synthetic antibodies To Be Published

8TMO

Cryo-EM structure of magnesium depleted CorA in complex with conformation-specific synthetic antibody C18, State MGD-1C
Descriptor:	Cobalt/magnesium transport protein CorA, MAGNESIUM ION, sAB C18 Heavy Chain, ...
Authors:	Erramilli, S.K, Perozo, E, Kossiakoff, A.A.
Deposit date:	2023-07-29
Release date:	2025-02-12
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Structural basis for CorA channel gating using conformation-specific synthetic antibodies To Be Published

8TMK

Cryo-EM structure of magnesium depleted CorA in complex with conformation-specific synthetic antibody C18, State MGD-2C
Descriptor:	Cobalt/magnesium transport protein CorA, MAGNESIUM ION, sAB C18 Heavy Chain, ...
Authors:	Erramilli, S.K, Perozo, E, Kossiakoff, A.A.
Deposit date:	2023-07-29
Release date:	2025-02-12
Method:	ELECTRON MICROSCOPY (3.4 Å)
Cite:	Structural basis for CorA channel gating using conformation-specific synthetic antibodies To Be Published

8TMM

Cryo-EM structure of magnesium depleted CorA in complex with conformation-specific synthetic antibody C18, State MGD-2A
Descriptor:	Cobalt/magnesium transport protein CorA, MAGNESIUM ION, sAB C18 Heavy Chain, ...
Authors:	Erramilli, S.K, Perozo, E, Kossiakoff, A.A.
Deposit date:	2023-07-29
Release date:	2025-02-12
Method:	ELECTRON MICROSCOPY (3.4 Å)
Cite:	Structural basis for CorA channel gating using conformation-specific synthetic antibodies To Be Published

8TMD

Cryo-EM structure of CorA in complex with conformation-specific synthetic antibody C18 and 100 uM MgCl2, State MG0.1-1A
Descriptor:	Cobalt/magnesium transport protein CorA, MAGNESIUM ION, sAB C18 Heavy Chain, ...
Authors:	Erramilli, S.K, Perozo, E, Kossiakoff, A.A.
Deposit date:	2023-07-29
Release date:	2025-02-12
Method:	ELECTRON MICROSCOPY (3 Å)
Cite:	Structural basis for CorA channel gating using conformation-specific synthetic antibodies To Be Published

8TMN

Cryo-EM structure of magnesium depleted CorA in complex with conformation-specific synthetic antibody C18, State MGD-1D
Descriptor:	Cobalt/magnesium transport protein CorA, MAGNESIUM ION, sAB C18 Heavy Chain, ...
Authors:	Erramilli, S.K, Perozo, E, Kossiakoff, A.A.
Deposit date:	2023-07-29
Release date:	2025-02-12
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Structural basis for CorA channel gating using conformation-specific synthetic antibodies To Be Published

8TML

Cryo-EM structure of magnesium depleted CorA in complex with conformation-specific synthetic antibody C18, State MGD-2B
Descriptor:	Cobalt/magnesium transport protein CorA, MAGNESIUM ION, sAB C18 Heavy Chain, ...
Authors:	Erramilli, S.K, Perozo, E, Kossiakoff, A.A.
Deposit date:	2023-07-29
Release date:	2025-02-12
Method:	ELECTRON MICROSCOPY (3.4 Å)
Cite:	Structural basis for CorA channel gating using conformation-specific synthetic antibodies To Be Published

8TME

Cryo-EM structure of CorA in complex with conformation-specific synthetic antibody C18 and 100 uM MgCl2, State MG0.1-1B
Descriptor:	Cobalt/magnesium transport protein CorA, MAGNESIUM ION, sAB C18 Heavy Chain, ...
Authors:	Erramilli, S.K, Perozo, E, Kossiakoff, A.A.
Deposit date:	2023-07-29
Release date:	2025-02-12
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Structural basis for CorA channel gating using conformation-specific synthetic antibodies To Be Published

8TMQ

Cryo-EM structure of magnesium depleted CorA in complex with conformation-specific synthetic antibody C18, State MGD-1A
Descriptor:	Cobalt/magnesium transport protein CorA, MAGNESIUM ION, sAB C18 Heavy Chain, ...
Authors:	Erramilli, S.K, Perozo, E, Kossiakoff, A.A.
Deposit date:	2023-07-29
Release date:	2025-02-12
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Structural basis for CorA channel gating using conformation-specific synthetic antibodies To Be Published

5PTP

STRUCTURE OF HYDROLASE (SERINE PROTEINASE)
Descriptor:	BETA TRYPSIN, CALCIUM ION
Authors:	Stroud, R.M, Finer-Moore, J.
Deposit date:	1997-03-31
Release date:	1997-07-07
Last modified:	2025-03-26
Method:	X-RAY DIFFRACTION (1.34 Å)
Cite:	Solvent structure in crystals of trypsin determined by X-ray and neutron diffraction. Proteins, 12, 1992

9MXV

Human Vault Cage in complex with ADP
Descriptor:	ADENOSINE-5'-DIPHOSPHATE, Major vault protein
Authors:	Lodwick, J.E, Zhao, M.
Deposit date:	2025-01-21
Release date:	2025-02-05
Method:	ELECTRON MICROSCOPY (2.68 Å)
Cite:	Structural Insights into the Roles of PARP4 and NAD + in the Human Vault Cage. Biorxiv, 2024

9MXH

Human Vault Cage in complex with NAD+
Descriptor:	Major vault protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:	Lodwick, J.E, Zhao, M.
Deposit date:	2025-01-20
Release date:	2025-02-05
Method:	ELECTRON MICROSCOPY (3.07 Å)
Cite:	Structural Insights into the Roles of PARP4 and NAD + in the Human Vault Cage. Biorxiv, 2024

1NAG

CREVICE-FORMING MUTANTS IN THE RIGID CORE OF BOVINE PANCREATIC TRYPSIN INHIBITOR: CRYSTAL STRUCTURES OF F22A, Y23A, N43G, AND F45A
Descriptor:	BOVINE PANCREATIC TRYPSIN INHIBITOR, PHOSPHATE ION
Authors:	Danishefsky, A.T, Wlodawer, A, Kim, K.-S, Tao, F, Woodward, C.
Deposit date:	1992-08-18
Release date:	1993-10-31
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A. Protein Sci., 2, 1993

8PTI

CRYSTAL STRUCTURE OF A Y35G MUTANT OF BOVINE PANCREATIC TRYPSIN INHIBITOR
Descriptor:	BOVINE PANCREATIC TRYPSIN INHIBITOR
Authors:	Housset, D, Kim, K.-S, Fuchs, J, Woodward, C, Wlodawer, A.
Deposit date:	1990-12-17
Release date:	1991-04-15
Last modified:	2024-11-20
Method:	X-RAY DIFFRACTION (1.8 Å)
Cite:	Crystal structure of a Y35G mutant of bovine pancreatic trypsin inhibitor. J.Mol.Biol., 220, 1991

5CWT

Crystal structure of Chaetomium thermophilum Nup57
Descriptor:	Nucleoporin NUP57
Authors:	Bley, C.J, Hoelz, A.
Deposit date:	2015-07-28
Release date:	2015-09-16
Last modified:	2024-03-06
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Architecture of the fungal nuclear pore inner ring complex. Science, 350, 2015

8JNK

Crystal structure of human ALKBH3 bound to ssDNA through active site crosslink
Descriptor:	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, DNA, MANGANESE (II) ION, ...
Authors:	Zhang, L.
Deposit date:	2023-06-06
Release date:	2024-01-24
Last modified:	2024-11-13
Method:	X-RAY DIFFRACTION (2.69 Å)
Cite:	The Molecular Basis of Human ALKBH3 Mediated RNA N 1 -methyladenosine (m 1 A) Demethylation. Angew.Chem.Int.Ed.Engl., 63, 2024

8JNR

Crystal structure of human ALKBH3 bound to 3mC containing ssDNA through distal crosslink
Descriptor:	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, DNA, MANGANESE (II) ION, ...
Authors:	Zhang, L.
Deposit date:	2023-06-06
Release date:	2024-01-24
Last modified:	2024-10-30
Method:	X-RAY DIFFRACTION (3.66 Å)
Cite:	The Molecular Basis of Human ALKBH3 Mediated RNA N 1 -methyladenosine (m 1 A) Demethylation. Angew.Chem.Int.Ed.Engl., 63, 2024

9MJB

Product-Bound mannosyltransferase PimE in complex with Fab
Descriptor:	(2S)-1-{[(S)-{[(1S,2R,3R,4S,5S,6R)-2-[(6-O-hexadecanoyl-beta-L-gulopyranosyl)oxy]-3,4,5-trihydroxy-6-{[beta-D-mannopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->6)-beta-D-mannopyranosyl-(1->6)-alpha-D-mannopyranosyl]oxy}cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}-3-(hexadecanoyloxy)propan-2-yl 10-methyloctadecanoate, Fab_E6 heavy chain, Fab_E6 light chain, ...
Authors:	Liu, Y, Mancia, F.
Deposit date:	2024-12-14
Release date:	2025-06-25
Method:	ELECTRON MICROSCOPY (3.46 Å)
Cite:	Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE. Nat Commun, 16, 2025

3PJS

Mechanism of Activation Gating in the Full-Length KcsA K+ Channel
Descriptor:	FAB heavy chain, FAB light chain, Voltage-gated potassium channel
Authors:	Uysal, S, Cuello, L.G, Kossiakoff, A, Perozo, E.
Deposit date:	2010-11-10
Release date:	2011-07-06
Last modified:	2024-11-20
Method:	X-RAY DIFFRACTION (3.8 Å)
Cite:	Mechanism of activation gating in the full-length KcsA K+ channel. Proc.Natl.Acad.Sci.USA, 108, 2011

7NIU

Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (apo-inward-open conformation)
Descriptor:	4B1 Fab-fragment heavy chain, 4B1 Fab-fragment light chain, CHOLESTEROL, ...
Authors:	Nosol, K, Locher, K.P.
Deposit date:	2021-02-14
Release date:	2021-08-25
Last modified:	2025-07-02
Method:	ELECTRON MICROSCOPY (4.2 Å)
Cite:	Structures of ABCB4 provide insight into phosphatidylcholine translocation. Proc.Natl.Acad.Sci.USA, 118, 2021

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