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5OCL
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BU of 5ocl by Molmil
Nanobody-anti-VGLUT nanobody complex
Descriptor: anti-llama nanobody, anti-vglut nanobody
Authors:Dutzler, R, Schenck, S, Kunz, L.
Deposit date:2017-07-03
Release date:2017-07-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Generation and Characterization of Anti-VGLUT Nanobodies Acting as Inhibitors of Transport.
Biochemistry, 56, 2017
6LFD
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BU of 6lfd by Molmil
Crystal structure of VMB-1 at pH5.5(Bis-Tris)
Descriptor: GLYCEROL, VMB-1, ZINC ION
Authors:Cheng, Q, Chen, S.
Deposit date:2019-12-02
Release date:2020-02-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of VMB-1 at pH 5.5(Bis-Tris)
To Be Published
6LF4
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BU of 6lf4 by Molmil
Crystal structure of VMB-1 bound to hydrolyzed meropenem
Descriptor: (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoy l)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid, VMB-1 metallo-beta-lactamase, ZINC ION
Authors:Cheng, Q, Chen, S.
Deposit date:2019-11-28
Release date:2020-03-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Crystal structure of VMB-1 bound to hydrolyzed meropenem
To Be Published
8K1Q
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BU of 8k1q by Molmil
Human TWIK-related acid-sensitive potassium channel TASK3 at pH 6.0, 5 mM KCl and 135 mM NaCl
Descriptor: CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, Potassium channel subfamily K member 9
Authors:Chen, S, Lin, H.
Deposit date:2023-07-11
Release date:2024-04-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.68 Å)
Cite:C-type inactivation and proton modulation mechanisms of the TASK3 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
8K1J
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BU of 8k1j by Molmil
Human TWIK-related acid-sensitive potassium channel TASK3 at pH 7.4,200 mM KCl
Descriptor: CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, Potassium channel subfamily K member 9
Authors:Chen, S, Lin, H.
Deposit date:2023-07-11
Release date:2024-04-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:C-type inactivation and proton modulation mechanisms of the TASK3 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
8K1Z
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BU of 8k1z by Molmil
Human TWIK-related acid-sensitive potassium channel TASK3 at pH 6.0, 200 mM KCl
Descriptor: CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, Potassium channel subfamily K member 9
Authors:Chen, S, Lin, H.
Deposit date:2023-07-11
Release date:2024-04-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.41 Å)
Cite:C-type inactivation and proton modulation mechanisms of the TASK3 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
8K1V
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BU of 8k1v by Molmil
Human TWIK-related acid-sensitive potassium channel TASK3 at pH 7.4, 5 mM KCl and 135 mM NaCl
Descriptor: CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, Potassium channel subfamily K member 9
Authors:Chen, S, Lin, H.
Deposit date:2023-07-11
Release date:2024-04-17
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.48 Å)
Cite:C-type inactivation and proton modulation mechanisms of the TASK3 channel.
Proc.Natl.Acad.Sci.USA, 121, 2024
6ZX9
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BU of 6zx9 by Molmil
Crystal structure of SIV Vpr,fused to T4 lysozyme, isolated from moustached monkey, bound to human DDB1 and human DCAF1 (amino acid residues 1046-1396)
Descriptor: DDB1- and CUL4-associated factor 1, DNA damage-binding protein 1, GLYCEROL, ...
Authors:Schwefel, D, Banchenko, S.
Deposit date:2020-07-29
Release date:2021-07-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.519729 Å)
Cite:Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses.
Plos Pathog., 17, 2021
8OJL
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BU of 8ojl by Molmil
Human Mitochondrial Lon Y394E Mutant ADP Bound
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E.
Deposit date:2023-03-24
Release date:2024-04-03
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (2.88 Å)
Cite:Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.
Sci Rep, 14, 2024
8OM7
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BU of 8om7 by Molmil
Human Mitochondrial Lon Y186E Mutant ADP Bound
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E.
Deposit date:2023-03-31
Release date:2024-04-10
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.74 Å)
Cite:Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.
Sci Rep, 14, 2024
8OKA
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BU of 8oka by Molmil
Human Mitochondrial Lon Y394F Mutant ADP Bound
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E.
Deposit date:2023-03-28
Release date:2024-04-10
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.89 Å)
Cite:Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.
Sci Rep, 14, 2024
8OVF
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BU of 8ovf by Molmil
Human Mitochondrial Lon Y186F Mutant ADP Bound
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial
Authors:Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E.
Deposit date:2023-04-26
Release date:2024-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (7.23 Å)
Cite:Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.
Sci Rep, 14, 2024
8OVG
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BU of 8ovg by Molmil
Human Mitochondrial Lon Y186E Mutant ADP Bound
Descriptor: Lon protease homolog, mitochondrial
Authors:Kereiche, S, Bauer, J.A, Matyas, P, Novacek, J, Kutejova, E.
Deposit date:2023-04-26
Release date:2024-05-08
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (8.47 Å)
Cite:Polyphosphate and tyrosine phosphorylation in the N-terminal domain of the human mitochondrial Lon protease disrupts its functions.
Sci Rep, 14, 2024
5VOV
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BU of 5vov by Molmil
Structure of AMPA receptor-TARP complex
Descriptor: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit
Authors:Zhao, Y, Chen, S, Wang, Y.S, Shekhar, M, Tajkhorshid, E, Gouaux, E.
Deposit date:2017-05-03
Release date:2017-07-12
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (7.7 Å)
Cite:Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM.
Cell, 170, 2017
4JLW
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BU of 4jlw by Molmil
Crystal structure of formaldehyde dehydrogenase from Pseudomonas aeruginosa
Descriptor: Glutathione-independent formaldehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
Authors:Chen, S, Liao, Y.P, Wang, D.L, Wang, S, Ding, J.F, Wang, Y.M, Cai, L.J, Ran, X.Y, Zhu, H.X.
Deposit date:2013-03-13
Release date:2013-10-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of formaldehyde dehydrogenase from Pseudomonas aeruginosa: the binary complex with the cofactor NAD+.
Acta Crystallogr.,Sect.F, 69, 2013
6M3M
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BU of 6m3m by Molmil
Crystal structure of SARS-CoV-2 nucleocapsid protein N-terminal RNA binding domain
Descriptor: Nucleoprotein
Authors:Chen, S, Kang, S.
Deposit date:2020-03-04
Release date:2020-03-18
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites.
Acta Pharm Sin B, 10, 2020
6K1M
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BU of 6k1m by Molmil
Engineered form of a putative cystathionine gamma-lyase
Descriptor: Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE, PYRUVIC ACID
Authors:Chen, S, Wang, Y.
Deposit date:2019-05-10
Release date:2020-05-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Structural characterization of cystathionine gamma-lyase smCSE enables aqueous metal quantum dot biosynthesis.
Int.J.Biol.Macromol., 174, 2021
6K1O
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BU of 6k1o by Molmil
Apo form of a putative cystathionine gamma-lyase
Descriptor: Cystathionine gamma-lyase
Authors:Chen, S, Wang, Y.
Deposit date:2019-05-10
Release date:2020-05-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.033 Å)
Cite:Structural characterization of cystathionine gamma-lyase smCSE enables aqueous metal quantum dot biosynthesis.
Int.J.Biol.Macromol., 174, 2021
6K1L
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BU of 6k1l by Molmil
E53A mutant of a putative cystathionine gamma-lyase
Descriptor: Cystathionine gamma-lyase, PYRIDOXAL-5'-PHOSPHATE, PYRUVIC ACID
Authors:Chen, S, Wang, Y.
Deposit date:2019-05-10
Release date:2020-05-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structural characterization of cystathionine gamma-lyase smCSE enables aqueous metal quantum dot biosynthesis.
Int.J.Biol.Macromol., 174, 2021
8TKL
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BU of 8tkl by Molmil
Murine NF-kappaB p50 Rel Homology Region homodimer in complex with a Test 16-mer kappaB-like DNA
Descriptor: Nuclear factor NF-kappa-B p50 subunit, Test 17-mer kappaB-like DNA
Authors:Mitchel, S, Mealka, M, Rogers, W.E, Milani, C, Acuna, L.M, Huxford, T.
Deposit date:2023-07-25
Release date:2023-10-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray Crystallographic Study of Preferred Spacing by the NF-kappa B p50 Homodimer on kappa B DNA.
Biomolecules, 13, 2023
6E5B
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BU of 6e5b by Molmil
Human Immunoproteasome 20S particle in complex with compound 1
Descriptor: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
Authors:Steinbacher, S, Augustin, M, Blaesse, M, Harris, S.F.
Deposit date:2018-07-19
Release date:2019-09-11
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Design and Evaluation of Highly Selective Human Immunoproteasome Inhibitors Reveal a Compensatory Process That Preserves Immune Cell Viability.
J.Med.Chem., 62, 2019
6HD3
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BU of 6hd3 by Molmil
Common mode of remodeling AAA ATPases p97/CDC48 by their disassembly cofactors ASPL/PUX1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 48 homolog A, PHOSPHATE ION
Authors:Heinemann, U, Roske, Y, Banchenko, S, Arumughan, A, Petrovic, S.
Deposit date:2018-08-17
Release date:2019-08-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Common Mode of Remodeling AAA ATPases p97/CDC48 by Their Disassembling Cofactors ASPL/PUX1.
Structure, 27, 2019
4JK5
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BU of 4jk5 by Molmil
Human urokinase-type Plasminogen Activator (uPA) in complex with a bicyclic peptide inhibitor (UK18-D-Ser)
Descriptor: 1,3,5-tris(bromomethyl)benzene, CHLORIDE ION, HEXAETHYLENE GLYCOL, ...
Authors:Buth, S.A, Leiman, P.G, Chen, S, Heinis, C.
Deposit date:2013-03-09
Release date:2013-07-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Improving binding affinity and stability of Peptide ligands by substituting glycines with d-amino acids.
Chembiochem, 14, 2013
4JK6
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BU of 4jk6 by Molmil
Human urokinase-type Plasminogen Activator (uPA) in complex with a bicyclic peptide inhibitor (UK18-D-Aba)
Descriptor: 1,3,5-tris(bromomethyl)benzene, CHLORIDE ION, HEXAETHYLENE GLYCOL, ...
Authors:Buth, S.A, Leiman, P.G, Chen, S, Heinis, C.
Deposit date:2013-03-09
Release date:2013-07-17
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Improving binding affinity and stability of Peptide ligands by substituting glycines with d-amino acids.
Chembiochem, 14, 2013
6HD0
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BU of 6hd0 by Molmil
Common mode of remodeling AAA ATPases p97/CDC48 by their disassembly cofactors ASPL/PUX1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Plant UBX domain-containing protein 1, Transitional endoplasmic reticulum ATPase
Authors:Heinemann, U, Roske, Y, Banchenko, S.
Deposit date:2018-08-17
Release date:2019-08-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.728 Å)
Cite:Common Mode of Remodeling AAA ATPases p97/CDC48 by Their Disassembling Cofactors ASPL/PUX1.
Structure, 27, 2019

222036

數據於2024-07-03公開中

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