1L9Z
| Thermus aquaticus RNA Polymerase Holoenzyme/Fork-Junction Promoter DNA Complex at 6.5 A Resolution | Descriptor: | MAGNESIUM ION, RNA POLYMERASE, ALPHA SUBUNIT, ... | Authors: | Murakami, K.S, Masuda, S, Campbell, E.A, Muzzin, O, Darst, S.A. | Deposit date: | 2002-03-27 | Release date: | 2002-05-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (6.5 Å) | Cite: | Structural basis of transcription initiation: an RNA polymerase holoenzyme-DNA complex. Science, 296, 2002
|
|
4KI2
| |
1OR7
| Crystal Structure of Escherichia coli sigmaE with the Cytoplasmic Domain of its Anti-sigma RseA | Descriptor: | RNA polymerase sigma-E factor, Sigma-E factor negative regulatory protein | Authors: | Campbell, E.A, Tupy, J.L, Gruber, T.M, Wang, S, Sharp, M.M, Gross, C.A, Darst, S.A. | Deposit date: | 2003-03-12 | Release date: | 2003-04-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of Escherichia coli sigmaE with the cytoplasmic domain of its anti-sigma RseA. Mol.Cell, 11, 2003
|
|
1RP3
| |
1RIO
| Structure of bacteriophage lambda cI-NTD in complex with sigma-region4 of Thermus aquaticus bound to DNA | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 27-MER, CALCIUM ION, ... | Authors: | Jain, D, Nickels, B.E, Sun, L, Hochschild, A, Darst, S.A. | Deposit date: | 2003-11-17 | Release date: | 2004-01-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of a ternary transcription activation complex. Mol.Cell, 13, 2004
|
|
1SC5
| Sigma-28(FliA)/FlgM complex | Descriptor: | RNA polymerase sigma factor FliA, anti-sigma factor FlgM | Authors: | Sorenson, M.K, Ray, S.S, Darst, S.A. | Deposit date: | 2004-02-11 | Release date: | 2004-04-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.26 Å) | Cite: | Crystal structure of the flagellar sigma/anti-sigma complex sigma(28)/FlgM reveals an intact sigma factor in an inactive conformation. Mol.Cell, 14, 2004
|
|
1TH8
| Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: inhibitory complex with ADP, crystal form II | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ... | Authors: | Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigian, J, Leon, F, Darst, S.A, Campbell, E.A. | Deposit date: | 2004-06-01 | Release date: | 2004-06-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA. J.Mol.Biol., 340, 2004
|
|
1TIL
| Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA:Poised for phosphorylation complex with ATP, crystal form II | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ... | Authors: | Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigan, J, Leon, F, Darst, S.A, Campbell, E.A. | Deposit date: | 2004-06-02 | Release date: | 2004-06-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA. J.Mol.Biol., 340, 2004
|
|
1THN
| Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: inhibitory complex with ADP, crystal form I | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ... | Authors: | Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigan, J, Leon, F, Darst, S.A, Campbell, E.A. | Deposit date: | 2004-06-01 | Release date: | 2004-06-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA. J.Mol.Biol., 340, 2004
|
|
1TID
| Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: Poised for phosphorylation complex with ATP, crystal form I | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Anti-sigma F factor, Anti-sigma F factor antagonist, ... | Authors: | Masuda, S, Murakami, K.S, Wang, S, Olson, C.A, Donigan, J, Leon, F, Darst, S.A, Campbell, E.A. | Deposit date: | 2004-06-02 | Release date: | 2004-06-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structures of the ADP and ATP Bound Forms of the Bacillus Anti-sigma Factor SpoIIAB in Complex with the Anti-anti-sigma SpoIIAA. J.Mol.Biol., 340, 2004
|
|
6OMF
| CryoEM structure of SigmaS-transcription initiation complex with activator Crl | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Jaramillo Cartagena, A, Darst, S.A, Campbell, E.A. | Deposit date: | 2019-04-18 | Release date: | 2019-08-28 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Structural basis for transcription activation by Crl through tethering of sigmaSand RNA polymerase. Proc.Natl.Acad.Sci.USA, 116, 2019
|
|
6OUL
| Cryo-EM structure of Escherichia coli RNAP polymerase bound to rpsTP2 promoter DNA | Descriptor: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | Deposit date: | 2019-05-04 | Release date: | 2020-02-26 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
|
|
7KIF
| Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 transcription factor | Descriptor: | DNA (55-MER), DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Lilic, M, Darst, S.A, Campbell, E.A. | Deposit date: | 2020-10-23 | Release date: | 2021-04-21 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
|
|
6P1K
| Cryo-EM structure of Escherichia coli sigma70 bound RNAP polymerase holoenzyme | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | Deposit date: | 2019-05-20 | Release date: | 2020-02-26 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.05 Å) | Cite: | E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
|
|
7KRP
| Structure of SARS-CoV-2 backtracked complex complex bound to nsp13 helicase - BTC (local refinement) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHAPSO, MAGNESIUM ION, ... | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | Deposit date: | 2020-11-20 | Release date: | 2021-04-21 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7KRO
| Structure of SARS-CoV-2 backtracked complex complex bound to nsp13 helicase - nsp13(2)-BTC | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ... | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | Deposit date: | 2020-11-20 | Release date: | 2021-04-21 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7KIN
| Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoter | Descriptor: | DNA (49-MER), DNA (54-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Lilic, M, Darst, S.A, Campbell, E.A. | Deposit date: | 2020-10-23 | Release date: | 2021-04-21 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
|
|
7KRN
| Structure of SARS-CoV-2 backtracked complex bound to nsp13 helicase - nsp13(1)-BTC | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, CHAPSO, ... | Authors: | Chen, J, Malone, B, Campbell, E.A, Darst, S.A. | Deposit date: | 2020-11-20 | Release date: | 2021-04-21 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7KIM
| Mycobacterium tuberculosis WT RNAP transcription closed promoter complex with WhiB7 transcription factor | Descriptor: | DNA (45-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Lilic, M, Darst, S.A, Campbell, E.A. | Deposit date: | 2020-10-23 | Release date: | 2021-04-21 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
|
|
6PSU
| Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi2) with TraR and rpsT P2 promoter | Descriptor: | CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | Deposit date: | 2019-07-13 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
|
|
6PSR
| Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1) with TraR and rpsT P2 promoter | Descriptor: | CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | Deposit date: | 2019-07-13 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
|
|
6PSW
| Escherichia coli RNA polymerase promoter unwinding intermediate (TRPo) with TraR and rpsT P2 promoter | Descriptor: | CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | Deposit date: | 2019-07-13 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
|
|
6PSS
| Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5a) with TraR and mutant rpsT P2 promoter | Descriptor: | DNA (85-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | Authors: | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | Deposit date: | 2019-07-13 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
|
|
6PSQ
| Escherichia coli RNA polymerase closed complex (TRPc) with TraR and rpsT P2 promoter | Descriptor: | CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | Deposit date: | 2019-07-13 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
|
|
6PST
| Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5b) with TraR and mutant rpsT P2 promoter | Descriptor: | CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... | Authors: | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | Deposit date: | 2019-07-13 | Release date: | 2020-03-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
|
|