5K7Y
 
 | | Crystal structure of enzyme in purine metabolism | | Descriptor: | Cytosolic purine 5'-nucleotidase, GLYCEROL | | Authors: | Skerlova, J, Hnizda, A, Pachl, P, Rezacova, P. | | Deposit date: | 2016-05-27 | | Release date: | 2016-09-21 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Oligomeric interface modulation causes misregulation of purine 5 -nucleotidase in relapsed leukemia.
Bmc Biol., 14, 2016
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6ZXP
 | | Solution structure of the C-terminal domain of the vaccinia virus DNA polymerase processivity factor component A20 fused to a short peptide from the viral DNA polymerase E9. | | Descriptor: | DNA polymerase processivity factor component A20,DNA polymerase processivity factor component E9 | | Authors: | Bersch, B, Tarbouriech, N, Burmeister, W, Iseni, F. | | Deposit date: | 2020-07-30 | | Release date: | 2021-05-19 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the C-terminal Domain of A20, the Missing Brick for the Characterization of the Interface between Vaccinia Virus DNA Polymerase and its Processivity Factor.
J.Mol.Biol., 433, 2021
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6ZYC
 | | Solution structure of the C-terminal domain of the vaccinia virus DNA polymerase processivity factor component A20. | | Descriptor: | DNA polymerase processivity factor component A20 | | Authors: | Bersch, B, Iseni, F, Burmeister, W, Tarbouriech, N. | | Deposit date: | 2020-07-31 | | Release date: | 2021-05-19 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of the C-terminal Domain of A20, the Missing Brick for the Characterization of the Interface between Vaccinia Virus DNA Polymerase and its Processivity Factor.
J.Mol.Biol., 433, 2021
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4PH4
 | | The crystal structure of Human VPS34 in complex with PIK-III | | Descriptor: | 4'-(cyclopropylmethyl)-N~2~-(pyridin-4-yl)-4,5'-bipyrimidine-2,2'-diamine, GLYCEROL, Phosphatidylinositol 3-kinase catalytic subunit type 3 | | Authors: | Knapp, M.S, Elling, R.A. | | Deposit date: | 2014-05-04 | | Release date: | 2014-10-29 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
Nat.Cell Biol., 16, 2014
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5L50
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9CWS
 | | Bufavirus 1 at pH 2.6 | | Descriptor: | VP1 | | Authors: | Gulkis, M.C, McKenna, R, Bennett, A.D. | | Deposit date: | 2024-07-30 | | Release date: | 2024-08-21 | | Method: | ELECTRON MICROSCOPY (2.73 Å) | | Cite: | Structural Characterization of Human Bufavirus 1: Receptor Binding and Endosomal pH-Induced Changes
Viruses, 16, 2024
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9CV9
 | | Bufavirus 1 at pH 4.0 | | Descriptor: | VP1 | | Authors: | Gulkis, M.C, McKenna, R, Bennett, A.D. | | Deposit date: | 2024-07-28 | | Release date: | 2024-08-28 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural Characterization of Human Bufavirus 1: Receptor Binding and Endosomal pH-Induced Changes
Viruses, 16, 2024
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9CGM
 | | The Structure of Spiroplasma Virus 4 | | Descriptor: | Capsid protein VP1, DNA binding protein ORF8 | | Authors: | Mietzsch, M, McKenna, R. | | Deposit date: | 2024-06-30 | | Release date: | 2024-07-17 | | Last modified: | 2024-08-07 | | Method: | ELECTRON MICROSCOPY (2.52 Å) | | Cite: | The Structure of Spiroplasma Virus 4 : Exploring the Capsid Diversity of the Microviridae.
Viruses, 16, 2024
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9CV0
 | | Bufavirus 1 at pH 7.4 | | Descriptor: | VP1 | | Authors: | Gulkis, M.C, McKenna, R, Bennett, A.D. | | Deposit date: | 2024-07-27 | | Release date: | 2024-08-28 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Structural Characterization of Human Bufavirus 1: Receptor Binding and Endosomal pH-Induced Changes
Viruses, 16, 2024
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7S1W
 | | The AAVrh.10-glycan complex | | Descriptor: | Capsid protein VP1, beta-D-galactopyranose | | Authors: | Mietzsch, M, McKenna, R. | | Deposit date: | 2021-09-02 | | Release date: | 2021-09-22 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Structural Study of Aavrh.10 Receptor and Antibody Interactions.
J.Virol., 95, 2021
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8Q4J
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8Q4I
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7PAY
 | | Structure of the human heterotetrameric cis-prenyltransferase complex in complex with magnesium and GGsPP | | Descriptor: | Dehydrodolichyl diphosphate synthase complex subunit DHDDS, Dehydrodolichyl diphosphate synthase complex subunit NUS1, MAGNESIUM ION, ... | | Authors: | Giladi, M, Lisnyansky Bar-El, M, Haitin, Y. | | Deposit date: | 2021-07-30 | | Release date: | 2022-06-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for long-chain isoprenoid synthesis by cis -prenyltransferases.
Sci Adv, 8, 2022
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7PAX
 | | Structure of the human heterotetrameric cis-prenyltransferase complex in complex with magnesium, FsPP and IPP | | Descriptor: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Dehydrodolichyl diphosphate synthase complex subunit DHDDS, Dehydrodolichyl diphosphate synthase complex subunit NUS1, ... | | Authors: | Giladi, M, Lisnyansky Bar-El, M, Haitin, Y. | | Deposit date: | 2021-07-30 | | Release date: | 2022-06-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis for long-chain isoprenoid synthesis by cis -prenyltransferases.
Sci Adv, 8, 2022
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7PB1
 | | Structure of the human heterotetrameric cis-prenyltransferase complex in complex with magnesium, GGPP and IsPP | | Descriptor: | 3-methylbut-3-enylsulfanyl(phosphonooxy)phosphinic acid, Dehydrodolichyl diphosphate synthase complex subunit DHDDS, Dehydrodolichyl diphosphate synthase complex subunit NUS1, ... | | Authors: | Giladi, M, Lisnyansky Bar-El, M, Haitin, Y. | | Deposit date: | 2021-07-30 | | Release date: | 2022-06-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.59 Å) | | Cite: | Structural basis for long-chain isoprenoid synthesis by cis -prenyltransferases.
Sci Adv, 8, 2022
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7PB0
 | | Structure of the human heterotetrameric cis-prenyltransferase complex in complex with magnesium, GGsPP and IsPP | | Descriptor: | 3-methylbut-3-enylsulfanyl(phosphonooxy)phosphinic acid, Dehydrodolichyl diphosphate synthase complex subunit DHDDS, Dehydrodolichyl diphosphate synthase complex subunit NUS1, ... | | Authors: | Giladi, M, Lisnyansky Bar-El, M, Haitin, Y. | | Deposit date: | 2021-07-30 | | Release date: | 2022-06-01 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.301 Å) | | Cite: | Structural basis for long-chain isoprenoid synthesis by cis -prenyltransferases.
Sci Adv, 8, 2022
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5M4S
 | | Transcription factor TFIIA as a single chain protein | | Descriptor: | Transcription initiation factor IIA subunit 2,Transcription initiation factor IIA subunit 1,Transcription initiation factor IIA subunit 1 | | Authors: | Kandiah, E, Gupta, K. | | Deposit date: | 2016-10-19 | | Release date: | 2017-11-29 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.38 Å) | | Cite: | Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.
Elife, 6, 2017
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5N2E
 | | Structure of the E9 DNA polymerase from vaccinia virus | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Tarbouriech, N, Burmeister, W.P, Iseni, F. | | Deposit date: | 2017-02-07 | | Release date: | 2017-11-29 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.74 Å) | | Cite: | The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding.
Nat Commun, 8, 2017
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5N2H
 | | Structure of the E9 DNA polymerase exonuclease deficient mutant (D166A+E168A) from vaccinia virus | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Tarbouriech, N, Burmeister, W.P, Iseni, F. | | Deposit date: | 2017-02-07 | | Release date: | 2017-11-29 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.81 Å) | | Cite: | The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding.
Nat Commun, 8, 2017
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5N2G
 | | Structure of the E9 DNA polymerase from vaccinia virus in complex with manganese | | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | Authors: | Tarbouriech, N, Burmeister, W.P, Iseni, F. | | Deposit date: | 2017-02-07 | | Release date: | 2017-11-29 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.78 Å) | | Cite: | The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding.
Nat Commun, 8, 2017
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6S9K
 | | Structure of 14-3-3 gamma in complex with caspase-2 peptide containing 14-3-3 binding motif Ser139 and NLS | | Descriptor: | 1,1,1,3,3,3-hexafluoropropan-2-ol, 14-3-3 protein gamma, Caspase-2 | | Authors: | Alblova, M, Obsil, T, Obsilova, V. | | Deposit date: | 2019-07-15 | | Release date: | 2020-01-22 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | 14-3-3 protein binding blocks the dimerization interface of caspase-2.
Febs J., 287, 2020
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6SAD
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5OAR
 | | Crystal structure of native beta-N-acetylhexosaminidase isolated from Aspergillus oryzae | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, ... | | Authors: | Skerlova, J, Rezacova, P, Brynda, J, Pachl, P, Otwinowski, Z, Vanek, O. | | Deposit date: | 2017-06-23 | | Release date: | 2017-12-27 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of native beta-N-acetylhexosaminidase isolated from Aspergillus oryzae sheds light onto its substrate specificity, high stability, and regulation by propeptide.
FEBS J., 285, 2018
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4U1D
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4U1C
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