7Q51
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![BU of 7q51 by Molmil](/molmil-images/mine/7q51) | yeast Gid10 bound to a Phe/N-peptide | Descriptor: | CHLORIDE ION, FWLPANLW peptide, Uncharacterized protein YGR066C | Authors: | Chrustowicz, J, Sherpa, D, Prabu, J.R, Schulman, B.A. | Deposit date: | 2021-11-02 | Release date: | 2022-03-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases. J.Mol.Biol., 434, 2022
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7Q0L
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![BU of 7q0l by Molmil](/molmil-images/mine/7q0l) | Crystal structure of the peptide transporter YePEPT-K314A at 2.93 A | Descriptor: | Peptide transporter YePEPT | Authors: | Jeckelmann, J.M, Stauffer, M, Ilgue, H, Boggavarapu, R, Fotiadis, D. | Deposit date: | 2021-10-15 | Release date: | 2022-03-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Peptide transporter structure reveals binding and action mechanism of a potent PEPT1 and PEPT2 inhibitor. Commun Chem, 5, 2022
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7Q50
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![BU of 7q50 by Molmil](/molmil-images/mine/7q50) | human Gid4 bound to a Phe/N-peptide | Descriptor: | FDVSWFMG peptide, Glucose-induced degradation protein 4 homolog | Authors: | Chrustowicz, J, Sherpa, D, Loke, M.S, Prabu, J.R, Schulman, B.A. | Deposit date: | 2021-11-02 | Release date: | 2022-03-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.16 Å) | Cite: | Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases. J.Mol.Biol., 434, 2022
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7Q0M
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![BU of 7q0m by Molmil](/molmil-images/mine/7q0m) | Crystal structure of the peptide transporter YePEPT-K314A in complex with LZNV at 2.66 A | Descriptor: | (2~{S})-2-[[(2~{S})-2-azanyl-6-[(4-nitrophenyl)methoxycarbonylamino]hexanoyl]amino]-3-methyl-butanoic acid, Peptide transporter YePEPT, UNDECYL-MALTOSIDE | Authors: | Jeckelmann, J.M, Stauffer, M, Ilgue, H, Fotiadis, D. | Deposit date: | 2021-10-15 | Release date: | 2022-03-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Peptide transporter structure reveals binding and action mechanism of a potent PEPT1 and PEPT2 inhibitor. Commun Chem, 5, 2022
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7Q4Y
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7Q1L
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![BU of 7q1l by Molmil](/molmil-images/mine/7q1l) | Glycosilated Human Serum Apo-tranferrin | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... | Authors: | Gavira, J.A, Moreno, A, Campos-Escamilla, C, Gonzalez-Ramirez, L.A, Siliqi, D. | Deposit date: | 2021-10-20 | Release date: | 2022-03-16 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | X-ray Characterization of Conformational Changes of Human Apo- and Holo-Transferrin. Int J Mol Sci, 22, 2021
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7V7L
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![BU of 7v7l by Molmil](/molmil-images/mine/7v7l) | Crystal Structure of the Heterodimeric HIF-3a:ARNT Complex | Descriptor: | Aryl hydrocarbon receptor nuclear translocator, Hypoxia-inducible factor 3-alpha | Authors: | Diao, X, Ren, X, Li, F.W, Sun, X, Wu, D. | Deposit date: | 2021-08-21 | Release date: | 2022-05-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Identification of oleoylethanolamide as an endogenous ligand for HIF-3 alpha. Nat Commun, 13, 2022
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7PSU
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![BU of 7psu by Molmil](/molmil-images/mine/7psu) | Structure of protein kinase CK2alpha mutant K198R associated with the Okur-Chung Neurodevelopmental Syndrome | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Casein kinase II subunit alpha, ... | Authors: | Werner, C, Gast, A, Lindenblatt, D, Nickelsen, K, Niefind, K, Jose, J, Hochscherf, J. | Deposit date: | 2021-09-23 | Release date: | 2022-03-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural and Enzymological Evidence for an Altered Substrate Specificity in Okur-Chung Neurodevelopmental Syndrome Mutant CK2 alpha Lys198Arg. Front Mol Biosci, 9, 2022
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6AJE
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![BU of 6aje by Molmil](/molmil-images/mine/6aje) | Crystal structure of DHODH in complex with ferulenol from Eimeria tenella | Descriptor: | 4-oxidanyl-3-[(2~{E},6~{E})-3,7,11-trimethyldodeca-2,6,10-trienyl]chromen-2-one, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | Authors: | Shiba, T, Inaoka, D.K, Sato, D, Hartuti, E.D, Amalia, E, Nagahama, M, Yoshioka, Y, Matsubayashi, M, Balogun, E.O, Tsuji, N, Kita, K, Harada, S. | Deposit date: | 2018-08-27 | Release date: | 2019-08-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Structural and Biochemical Features of Eimeria tenella Dihydroorotate Dehydrogenase, a Potential Drug Target. Genes (Basel), 11, 2020
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7VLT
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![BU of 7vlt by Molmil](/molmil-images/mine/7vlt) | Structure of SUR2B in complex with Mg-ATP/ADP and levcromakalim | Descriptor: | (3S,4R)-2,2-dimethyl-3-oxidanyl-4-(2-oxidanylidenepyrrolidin-1-yl)-3,4-dihydrochromene-6-carbonitrile, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Chen, L, Ding, D. | Deposit date: | 2021-10-05 | Release date: | 2022-05-18 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural identification of vasodilator binding sites on the SUR2 subunit. Nat Commun, 13, 2022
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5ZUR
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![BU of 5zur by Molmil](/molmil-images/mine/5zur) | Achromobacter Dh1f Bacterioferritin | Descriptor: | BARIUM ION, Bacterioferritin, CHLORIDE ION, ... | Authors: | Dwivedy, A, Jha, B, Singh, K.H, Ahmed, M, Ashraf, A, Kumar, D, Biswal, B.K. | Deposit date: | 2018-05-08 | Release date: | 2018-09-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Serendipitous crystallization and structure determination of bacterioferritin from Achromobacter. Acta Crystallogr F Struct Biol Commun, 74, 2018
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7VLR
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![BU of 7vlr by Molmil](/molmil-images/mine/7vlr) | Structure of SUR2B in complex with Mg-ATP/ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Chen, L, Ding, D. | Deposit date: | 2021-10-05 | Release date: | 2022-05-18 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural identification of vasodilator binding sites on the SUR2 subunit. Nat Commun, 13, 2022
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7PLM
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![BU of 7plm by Molmil](/molmil-images/mine/7plm) | CryoEM reconstruction of pyruvate ferredoxin oxidoreductase (PFOR) in anaerobic conditions | Descriptor: | CALCIUM ION, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | Authors: | Cherrier, M.V, Vernede, X, Fenel, D, Martin, L, Arragain, B, Neumann, E, Fontecilla Camps, J.C, Schoehn, G, Nicolet, Y. | Deposit date: | 2021-08-31 | Release date: | 2022-03-23 | Last modified: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Oxygen-Sensitive Metalloprotein Structure Determination by Cryo-Electron Microscopy. Biomolecules, 12, 2022
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7VLU
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![BU of 7vlu by Molmil](/molmil-images/mine/7vlu) | Structure of SUR2A in complex with Mg-ATP/ADP and P1075 | Descriptor: | 1-cyano-2-(2-methylbutan-2-yl)-3-pyridin-3-yl-guanidine, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Chen, L, Ding, D. | Deposit date: | 2021-10-05 | Release date: | 2022-05-18 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural identification of vasodilator binding sites on the SUR2 subunit. Nat Commun, 13, 2022
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5ZXM
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![BU of 5zxm by Molmil](/molmil-images/mine/5zxm) | Crystal Structure of GyraseB N-terminal at 1.93A Resolution | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA gyrase subunit B, ... | Authors: | Tiwari, P, Gupta, D, Sachdeva, E, Sharma, S, Singh, T.P, Ethayathulla, A.S, Kaur, P. | Deposit date: | 2018-05-21 | Release date: | 2019-05-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.938 Å) | Cite: | Structural insights into the transient closed conformation and pH dependent ATPase activity of S.Typhi GyraseB N- terminal domain. Arch.Biochem.Biophys., 701, 2021
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7VLS
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![BU of 7vls by Molmil](/molmil-images/mine/7vls) | Structure of SUR2B in complex with MgATP/ADP and P1075 | Descriptor: | 1-cyano-2-(2-methylbutan-2-yl)-3-pyridin-3-yl-guanidine, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Chen, L, Ding, D. | Deposit date: | 2021-10-05 | Release date: | 2022-05-18 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural identification of vasodilator binding sites on the SUR2 subunit. Nat Commun, 13, 2022
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5ZYH
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![BU of 5zyh by Molmil](/molmil-images/mine/5zyh) | Crystal structure of CERT START domain in complex with compound E5 | Descriptor: | 2-[4-[3-~{tert}-butyl-5-[(1~{R},2~{S})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, LIPID-TRANSFER PROTEIN CERT | Authors: | Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K. | Deposit date: | 2018-05-25 | Release date: | 2019-02-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT Commun Chem, 2019
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7VX8
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![BU of 7vx8 by Molmil](/molmil-images/mine/7vx8) | Cryo-EM structure of ATP-bound human very long-chain fatty acid ABC transporter ABCD1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1 | Authors: | Chen, Z.P, Xu, D, Wang, L, Mao, Y.X, Yang, L, Cheng, M.T, Hou, W.T, Chen, Y.X, Zhou, C.Z. | Deposit date: | 2021-11-12 | Release date: | 2022-05-18 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1. Nat Commun, 13, 2022
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5ZYK
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![BU of 5zyk by Molmil](/molmil-images/mine/5zyk) | Crystal structure of CERT START domain in complex with compound E25 | Descriptor: | 2-[4-[4-cyclopentyl-3-[(1~{S},2~{R})-2-pyridin-2-ylcyclopropyl]phenyl]phenyl]sulfonylethanol, LIPID-TRANSFER PROTEIN CERT | Authors: | Suzuki, M, Nakao, N, Ueno, M, Sakai, S, Egawa, D, Hanzawa, H, Kawasaki, S, Kumagai, K, Kobayashi, S, Hanada, K. | Deposit date: | 2018-05-25 | Release date: | 2019-02-27 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT Commun Chem, 2019
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7V7W
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![BU of 7v7w by Molmil](/molmil-images/mine/7v7w) | Crystal Structure of the Heterodimeric HIF-3a:ARNT Complex with oleoylethanolamide (OEA) | Descriptor: | (Z)-N-(2-hydroxyethyl)octadec-9-enamide, Aryl hydrocarbon receptor nuclear translocator, Hypoxia-inducible factor 3-alpha | Authors: | Diao, X, Ren, X, Li, F.W, Zhang, M, Sun, X, Wu, D. | Deposit date: | 2021-08-21 | Release date: | 2022-05-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.507 Å) | Cite: | Identification of oleoylethanolamide as an endogenous ligand for HIF-3 alpha. Nat Commun, 13, 2022
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7VWC
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![BU of 7vwc by Molmil](/molmil-images/mine/7vwc) | Cryo-EM structure of human very long-chain fatty acid ABC transporter ABCD1 | Descriptor: | Peroxisomal Membrane Protein related,ATP-binding cassette sub-family D member 1, [(2R)-3-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-2-oxidanyl-propyl] octadecanoate | Authors: | Chen, Z.P, Xu, D, Wang, L, Mao, Y.X, Yang, L, Cheng, M.T, Hou, W.T, Chen, Y.X, Zhou, C.Z. | Deposit date: | 2021-11-10 | Release date: | 2022-05-18 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1. Nat Commun, 13, 2022
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7EME
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![BU of 7eme by Molmil](/molmil-images/mine/7eme) | Putative Leptospira interrogans recombinant L-amino acid oxidase | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)/FAD-dependent oxidoreductase | Authors: | Vaigundan, D, Yuvaraj, I, Krishnaswamy, P.R, Sekar, K, Murthy, M.R.N, Sunita, P. | Deposit date: | 2021-04-13 | Release date: | 2021-08-18 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Structural characterization of a putative recombinant L-amino acid oxidase from Leptospira interrogans Curr.Sci., 123, 2022
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7VU8
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![BU of 7vu8 by Molmil](/molmil-images/mine/7vu8) | L7-Tir domain with bound ligand | Descriptor: | 2',3'- cyclic AMP, Flax rust resistance protein | Authors: | Tan, Y, Xu, C, Yu, D, Song, W, Wu, B, Schulze-Lefert, P, Chai, J. | Deposit date: | 2021-11-01 | Release date: | 2022-06-01 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | TIR domains of plant immune receptors are 2',3'-cAMP/cGMP synthetases mediating cell death. Cell, 185, 2022
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6A8N
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![BU of 6a8n by Molmil](/molmil-images/mine/6a8n) | The crystal structure of muPAin-1-IG-2 in complex with muPA-SPD at pH8.5 | Descriptor: | CYS-PRO-ALA-TYR-SER-ARG-TYR-ILE-GLY-CYS, Urokinase-type plasminogen activator B | Authors: | Wang, D, Yang, Y.S, Jiang, L.G, Huang, M.D, Li, J.Y, Andreasen, P.A, Xu, P, Chen, Z. | Deposit date: | 2018-07-09 | Release date: | 2019-02-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.489 Å) | Cite: | Suppression of Tumor Growth and Metastases by Targeted Intervention in Urokinase Activity with Cyclic Peptides. J.Med.Chem., 62, 2019
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7VIU
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![BU of 7viu by Molmil](/molmil-images/mine/7viu) | Crystal structure of Au(200EQ)-apo-R168C/L169C-rHLFr | Descriptor: | CADMIUM ION, CHLORIDE ION, Ferritin light chain, ... | Authors: | Lu, C, Peng, X, Maity, B, Ito, N, Abe, S, Ueno, T, Lu, D. | Deposit date: | 2021-09-27 | Release date: | 2022-06-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Design of a gold clustering site in an engineered apo-ferritin cage. Commun Chem, 5, 2022
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