4MZH
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4MZF
| Crystal structure of human Spindlin1 bound to histone H3(K4me3-R8me2a) peptide | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Peptide from Histone H3.2, ... | Authors: | Su, X, Ding, X, Li, H. | Deposit date: | 2013-09-30 | Release date: | 2014-03-26 | Method: | X-RAY DIFFRACTION (2.098 Å) | Cite: | Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1 Genes Dev., 28, 2014
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4MZG
| Crystal structure of human Spindlin1 bound to histone H3K4me3 peptide | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... | Authors: | Su, X, Ding, X, Li, H. | Deposit date: | 2013-09-30 | Release date: | 2014-03-26 | Method: | X-RAY DIFFRACTION (1.698 Å) | Cite: | Molecular basis underlying histone H3 lysine-arginine methylation pattern readout by Spin/Ssty repeats of Spindlin1 Genes Dev., 28, 2014
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4NRM
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7RTN
| Cryo-EM structure of bluetongue virus capsid protein VP5 at low endosomal pH | Descriptor: | Outer capsid protein VP5 | Authors: | Xia, X, Wu, W.N, Cui, Y.X, Roy, P, Zhou, Z.H. | Deposit date: | 2021-08-13 | Release date: | 2021-11-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Bluetongue virus capsid protein VP5 perforates membranes at low endosomal pH during viral entry. Nat Microbiol, 6, 2021
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7RTO
| Cryo-EM structure of bluetongue virus capsid protein VP5 at low endosomal pH intermediate state 2 | Descriptor: | Outer capsid protein VP5 | Authors: | Xia, X, Wu, W.N, Cui, Y.X, Roy, P, Zhou, Z.H. | Deposit date: | 2021-08-13 | Release date: | 2021-11-03 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Bluetongue virus capsid protein VP5 perforates membranes at low endosomal pH during viral entry. Nat Microbiol, 6, 2021
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8HAZ
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8HBB
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8HB2
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8KA4
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4NQJ
| Structure of coiled-coil domain | Descriptor: | DODECYL-BETA-D-MALTOSIDE, E3 ubiquitin-protein ligase TRIM69 | Authors: | Yang, M, Li, Y. | Deposit date: | 2013-11-25 | Release date: | 2014-05-21 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.152 Å) | Cite: | Structural insights into the TRIM family of ubiquitin E3 ligases. Cell Res., 24, 2014
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8KA3
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8KA5
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7MXD
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7N28
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6M1S
| The DNA Gyrase B ATP binding domain of PSEUDOMONAS AERUGINOSA in complex with compound 12o | Descriptor: | 3-[5-[8-(ethylamino)-6-fluoranyl-4-[3-(trifluoromethyl)pyrazol-1-yl]-9H-pyrido[2,3-b]indol-3-yl]pyrimidin-2-yl]oxy-2,2-dimethyl-propanoic acid, CHLORIDE ION, DNA gyrase subunit B, ... | Authors: | Xu, Z.H, Zhou, Z. | Deposit date: | 2020-02-26 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.254 Å) | Cite: | Discovery of Pyrido[2,3-b]indole Derivatives with Gram-Negative Activity Targeting Both DNA Gyrase and Topoisomerase IV. J.Med.Chem., 63, 2020
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4X32
| Bacteriorhodopsin ground state structure collected in cryo conditions from crystals obtained in LCP with PEG as a precipitant. | Descriptor: | 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, Bacteriorhodopsin, RETINAL | Authors: | Nogly, P, Standfuss, J. | Deposit date: | 2014-11-27 | Release date: | 2015-02-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Lipidic cubic phase serial millisecond crystallography using synchrotron radiation. Iucrj, 2, 2015
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6U6O
| Crystal structure of a vaccine-elicited anti-HIV-1 rhesus macaque antibody DH846 | Descriptor: | DH846 Fab heavy chain, DH846 Fab light chain | Authors: | Chen, W.-H, Choe, M, Saunders, K.O, Joyce, M.G. | Deposit date: | 2019-08-30 | Release date: | 2021-03-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.806 Å) | Cite: | Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates. Plos Pathog., 17, 2021
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6U6M
| Crystal structure of a vaccine-elicited anti-HIV-1 rhesus macaque antibody DH840.1 | Descriptor: | DH840.1 Fab heavy chain, DH840.1 Fab light chain | Authors: | Chen, W.-H, Choe, M, Saunders, K.O, Joyce, M.G. | Deposit date: | 2019-08-30 | Release date: | 2021-03-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.683 Å) | Cite: | Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates. Plos Pathog., 17, 2021
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3LON
| HCV NS3-4a protease domain with ketoamide inhibitor narlaprevir | Descriptor: | (1R,2S,5S)-3-[N-({1-[(tert-butylsulfonyl)methyl]cyclohexyl}carbamoyl)-3-methyl-L-valyl]-N-{(1S)-1-[(1R)-2-(cyclopropylamino)-1-hydroxy-2-oxoethyl]pentyl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide, BETA-MERCAPTOETHANOL, Genome polyprotein, ... | Authors: | Prongay, A.J. | Deposit date: | 2010-02-04 | Release date: | 2011-01-19 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Candidate selection and preclinical evaluation culminating in the discovery of Narlaprevir (SCH 900518): A potent, selective and orally efficacious second generation HCV NS3 serine protease inhibitor To be Published
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4XXB
| Crystal structure of human MDM2-RPL11 | Descriptor: | 60S ribosomal protein L11, BETA-MERCAPTOETHANOL, E3 ubiquitin-protein ligase Mdm2, ... | Authors: | Zheng, J, Chen, Z. | Deposit date: | 2015-01-30 | Release date: | 2015-08-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation Genes Dev., 29, 2015
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6KXS
| Cryo-EM structure of human IgM-Fc in complex with the J chain and the ectodomain of pIgR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | Authors: | Li, Y, Wang, G, Xiao, J. | Deposit date: | 2019-09-12 | Release date: | 2020-02-05 | Last modified: | 2021-12-15 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into immunoglobulin M. Science, 367, 2020
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6LOH
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7RGW
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2NAE
| Membrane-bound mouse CD28 cytoplasmic tail | Descriptor: | T-cell-specific surface glycoprotein CD28 | Authors: | Li, H, Xu, C, Pan, W. | Deposit date: | 2015-12-23 | Release date: | 2016-12-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Dynamic regulation of CD28 conformation and signaling by charged lipids and ions. Nat.Struct.Mol.Biol., 24, 2017
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