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1Y51
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BU of 1y51 by Molmil
X-ray crystal structure of Bacillus stearothermophilus Histidine phosphocarrier protein (Hpr) F29W mutant
Descriptor: Phosphocarrier protein HPr, SULFATE ION
Authors:Sridharan, S, Razvi, A, Scholtz, J.M, Sacchettini, J.C.
Deposit date:2004-12-01
Release date:2005-02-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The HPr proteins from the thermophile Bacillus stearothermophilus can form domain-swapped dimers.
J.Mol.Biol., 346, 2005
4B1M
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BU of 4b1m by Molmil
CARBOHYDRATE BINDING MODULE CBM66 FROM BACILLUS SUBTILIS
Descriptor: LEVANASE, SODIUM ION, SULFATE ION, ...
Authors:Cuskin, F, Flint, J.E, Morland, C, Basle, A, Henrissat, B, Countinho, P.M, Strazzulli, A, Solzehinkin, A, Davies, G.J, Gilbert, H.J, Gloster, T.M.
Deposit date:2012-07-11
Release date:2012-12-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:How Nature Can Exploit Nonspecific Catalytic and Carbohydrate Binding Modules to Create Enzymatic Specificity
Proc.Natl.Acad.Sci.USA, 109, 2012
4B1L
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BU of 4b1l by Molmil
CARBOHYDRATE BINDING MODULE CBM66 FROM BACILLUS SUBTILIS
Descriptor: LEVANASE, SODIUM ION, beta-D-fructofuranose
Authors:Cuskin, F, Flint, J.E, Morland, C, Basle, A, Henrissat, B, Countinho, P.M, Strazzulli, A, Solzehinkin, A, Davies, G.J, Gilbert, H.J, Gloster, T.M.
Deposit date:2012-07-11
Release date:2012-12-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:How Nature Can Exploit Nonspecific Catalytic and Carbohydrate Binding Modules to Create Enzymatic Specificity
Proc.Natl.Acad.Sci.USA, 109, 2012
4AQF
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BU of 4aqf by Molmil
X-ray crystallographic structure of Crimean-congo haemorrhagic fever virus nucleoprotein
Descriptor: NUCLEOPROTEIN, SULFATE ION
Authors:Wang, Y, Dutta, S, Karlberg, H, Devignot, S, Weber, F, Hao, Q, Tan, Y.J, Mirazimi, A, Kotaka, M.
Deposit date:2012-04-17
Release date:2012-09-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of Crimean-Congo Haemorraghic Fever Virus Nucleoprotein: Superhelical Homo-Oligomers and the Role of Caspase-3 Cleavage.
J.Virol., 86, 2012
4AQG
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BU of 4aqg by Molmil
X-ray crystallographic structure of Crimean-congo haemorrhagic fever virus nucleoprotein
Descriptor: NUCLEOPROTEIN, SULFATE ION
Authors:Wang, Y, Dutta, S, Karlberg, H, Devignot, S, Weber, F, Hao, Q, Tan, Y.J, Mirazimi, A, Kotaka, M.
Deposit date:2012-04-17
Release date:2012-09-26
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Crimean-Congo Haemorraghic Fever Virus Nucleoprotein: Superhelical Homo-Oligomers and the Role of Caspase-3 Cleavage.
J.Virol., 86, 2012
2W9D
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BU of 2w9d by Molmil
Structure of Fab fragment of the ICSM 18 - anti-Prp therapeutic antibody at 1.57 A resolution.
Descriptor: CALCIUM ION, ICSM 18-ANTI-PRP THERAPEUTIC FAB HEAVY CHAIN, ICSM 18-ANTI-PRP THERAPEUTIC FAB LIGHT CHAIN
Authors:Antonyuk, S.V, Trevitt, C.R, Strange, R.W, Jackson, G.S, Sangar, D, Batchelor, M, Jones, S, Georgiou, T, Cooper, S, Fraser, C, Khalili-Shirazi, A, Clarke, A.R, Hasnain, S.S, Collinge, J.
Deposit date:2009-01-23
Release date:2009-02-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Crystal Structure of Human Prion Protein Bound to a Therapeutic Antibody.
Proc.Natl.Acad.Sci.USA, 106, 2009
2W9E
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BU of 2w9e by Molmil
Structure of ICSM 18 (anti-Prp therapeutic antibody) Fab fragment complexed with human Prp fragment 119-231
Descriptor: ICSM 18-ANTI-PRP THERAPEUTIC FAB HEAVY CHAIN, ICSM 18-ANTI-PRP THERAPEUTIC FAB LIGHT CHAIN, MAJOR PRION PROTEIN, ...
Authors:Antonyuk, S.V, Trevitt, C.R, Strange, R.W, Jackson, G.S, Sangar, D, Batchelor, M, Jones, S, Georgiou, T, Cooper, S, Fraser, C, Khalili-Shirazi, A, Clarke, A.R, Hasnain, S.S, Collinge, J.
Deposit date:2009-01-23
Release date:2009-02-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of Human Prion Protein Bound to a Therapeutic Antibody.
Proc.Natl.Acad.Sci.USA, 106, 2009
2WJZ
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BU of 2wjz by Molmil
Crystal structure of (HisH) K181A Y138A mutant of imidazoleglycerolphosphate synthase (HisH HisF) which displays constitutive glutaminase activity
Descriptor: IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE HISF, IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE SUBUNIT HISH, PHOSPHATE ION
Authors:Vega, M.C, List, F, Razeto, A, Haeger, M.C, Babinger, K, Kuper, J, Sterner, R, Wilmanns, M.
Deposit date:2009-06-02
Release date:2010-08-25
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Catalysis Uncoupling in a Glutamine Amidotransferase Bienzyme by Unblocking the Glutaminase Active Site.
Chem.Biol., 19, 2012
6NQB
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BU of 6nqb by Molmil
Role of Era in Assembly and Homeostasis of the Ribosomal Small Subunit
Descriptor: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN bS16, 30S ribosomal protein S10, ...
Authors:Ortega, J.
Deposit date:2019-01-20
Release date:2019-06-26
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Role of Era in assembly and homeostasis of the ribosomal small subunit.
Nucleic Acids Res., 47, 2019
2BJE
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BU of 2bje by Molmil
Acylphosphatase from Sulfolobus solfataricus. Monclinic P21 space group
Descriptor: ACYLPHOSPHATASE, CHLORIDE ION, SULFATE ION
Authors:Rosano, C, Zuccotti, S.
Deposit date:2005-02-02
Release date:2005-11-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure, Conformational Stability, and Enzymatic Properties of Acylphosphatase from the Hyperthermophile Sulfolobus Solfataricus.
Proteins: Struct., Funct., Bioinf., 62, 2006
2BJD
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BU of 2bjd by Molmil
Sulfolobus Solfataricus Acylphosphatase. Triclinic space group
Descriptor: ACYLPHOSPHATASE, CADMIUM ION, CHLORIDE ION, ...
Authors:Rosano, C, Zuccotti, S, Bolognesi, M.
Deposit date:2005-02-02
Release date:2005-11-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.27 Å)
Cite:Structure, Conformational Stability, and Enzymatic Properties of Acylphosphatase from the Hyperthermophile Sulfolobus Solfataricus.
Proteins: Struct., Funct., Bioinf., 62, 2006
5YC5
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BU of 5yc5 by Molmil
Crystal structure of human IgG-Fc in complex with aglycan and optimized Fc gamma receptor IIIa
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Immunoglobulin gamma-1 heavy chain, ...
Authors:Caaveiro, J.M.M, Tamura, H, Tsumoto, K, Kiyoshi, M.
Deposit date:2017-09-06
Release date:2018-03-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Assessing the Heterogeneity of the Fc-Glycan of a Therapeutic Antibody Using an engineered Fc gamma Receptor IIIa-Immobilized Column.
Sci Rep, 8, 2018
5CKA
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BU of 5cka by Molmil
Human beta-2 microglobulin double mutant W60G-N83V
Descriptor: ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ...
Authors:Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-15
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
5CKG
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BU of 5ckg by Molmil
Human beta-2 microglobulin mutant V85E
Descriptor: ACETATE ION, Beta-2-microglobulin, GLYCEROL
Authors:Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-15
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
5CFH
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BU of 5cfh by Molmil
human beta-2 microglobulin double mutant W60G-Y63W
Descriptor: Beta-2-microglobulin
Authors:Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S.
Deposit date:2015-07-08
Release date:2016-05-18
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
7ZN7
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BU of 7zn7 by Molmil
Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and rat STAT2 CCD
Descriptor: B27a, DNA damage-binding protein 1, Signal transducer and activator of transcription, ...
Authors:Lauer, S, Spahn, C.M.T, Schwefel, D.
Deposit date:2022-04-20
Release date:2022-11-09
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor.
Embo J., 42, 2023
7ZNN
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BU of 7znn by Molmil
Cryo-EM structure of RCMV-E E27 bound to human DDB1 (deltaBPB) and full-length rat STAT2
Descriptor: B27a, DNA damage-binding protein 1, Signal transducer and activator of transcription, ...
Authors:Lauer, S, Spahn, C.M.T, Schwefel, D.
Deposit date:2022-04-21
Release date:2022-11-09
Last modified:2023-03-15
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural mechanism of CRL4-instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor.
Embo J., 42, 2023
8CBH
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BU of 8cbh by Molmil
SHP2 in complex with a novel allosteric inhibitor
Descriptor: Tyrosine-protein phosphatase non-receptor type 11, [(1~{S},6~{R},7~{S})-3-[3-[2,3-bis(chloranyl)phenyl]-2~{H}-pyrazolo[3,4-b]pyrazin-6-yl]-7-(4-methyl-1,3-thiazol-2-yl)-3-azabicyclo[4.1.0]heptan-7-yl]methanamine
Authors:di Fabio, R, Petrocchi, A.
Deposit date:2023-01-25
Release date:2023-04-26
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Discovery of a Novel Series of Imidazopyrazine Derivatives as Potent SHP2 Allosteric Inhibitors.
Acs Med.Chem.Lett., 14, 2023
7Z0W
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BU of 7z0w by Molmil
E. coli NfsA bound to NADP+
Descriptor: 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, MAGNESIUM ION, ...
Authors:White, S.A, Grainger, A, Parr, R, Day, M.A, Jarrom, D, Graziano, A, Searle, P.F, Hyde, E.I.
Deposit date:2022-02-23
Release date:2022-07-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:The 3D-structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP + provide glimpses of its catalytic mechanism.
Febs Lett., 596, 2022
6PPK
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BU of 6ppk by Molmil
RbgA+45SRbgA complex
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Ortega, J.
Deposit date:2019-07-07
Release date:2019-09-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural consequences of the interaction of RbgA with a 50S ribosomal subunit assembly intermediate.
Nucleic Acids Res., 47, 2019
6BEK
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BU of 6bek by Molmil
Structure of sIHF bound to an 8bp palindromic DNA
Descriptor: DNA (5'-D(*CP*AP*TP*GP*CP*AP*TP*G)-3'), POTASSIUM ION, SCO1480
Authors:Guarne, A, Nanji, T.N, Shen, Y.
Deposit date:2017-10-25
Release date:2018-10-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Streptomyces IHF uses multiple interfaces to bind DNA.
Biochim Biophys Acta Gen Subj, 1863, 2019
3ECW
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BU of 3ecw by Molmil
Crystal structure of the ALS-related pathological mutant T54R of human apo Cu,Zn Superoxide Dismutase (SOD1)
Descriptor: Superoxide dismutase [Cu-Zn]
Authors:Calderone, V.
Deposit date:2008-09-02
Release date:2009-05-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and dynamic aspects related to oligomerization of apo SOD1 and its mutants.
Proc.Natl.Acad.Sci.USA, 106, 2009
8OMV
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BU of 8omv by Molmil
Crystal structure of the constitutively active S117E/S181E mutant of human IKK2
Descriptor: Inhibitor of nuclear factor kappa-B kinase subunit beta
Authors:McEwen, A.G, Li, C, Moro, S, Poussin-Courmontagne, P, Zanier, K.
Deposit date:2023-03-31
Release date:2024-04-10
Method:X-RAY DIFFRACTION (4.16 Å)
Cite:A novel YDD(phi)X(phi) linear motif mediates docking of IKK catalytic dimers to NF-kappaB substrates: structural and functional insights
To be published
7Q0O
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BU of 7q0o by Molmil
E. coli NfsA
Descriptor: FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NADPH nitroreductase
Authors:White, S.A, Grainger, A, Parr, R, Day, M.A, Jarrom, D, Graziano, A, Searle, P.F, Hyde, E.I.
Deposit date:2021-10-15
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (0.96 Å)
Cite:The 3D-structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP + provide glimpses of its catalytic mechanism.
Febs Lett., 596, 2022
4YPI
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BU of 4ypi by Molmil
Structure of Ebola virus nucleoprotein N-terminal fragment bound to a peptide derived from Ebola VP35
Descriptor: Nucleoprotein, Polymerase cofactor VP35
Authors:Leung, D.W, Borek, D.M, Binning, J.M, Otwinowski, Z, Amarasinghe, G.K, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2015-03-13
Release date:2015-04-08
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (3.71 Å)
Cite:An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions.
Cell Rep, 11, 2015

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數據於2024-06-19公開中

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