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4M43
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BU of 4m43 by Molmil
Crystal structure of anti-rabies glycoprotein Fab 523-11
Descriptor: Fragment antigen-binding 523-11 heavy chain, Fragment antigen-binding 523-11 light chain, GLYCEROL, ...
Authors:Stanfield, R.L, Wilson, I.A, Wunner, W.H.
Deposit date:2013-08-06
Release date:2013-08-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of anti-rabies glycoprotein Fab 523-11
To be Published
4MHI
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BU of 4mhi by Molmil
Crystal structure of a H5N1 influenza virus hemagglutinin from A/goose/Guangdong/1/96
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-08-29
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.595 Å)
Cite:A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin.
J.Virol., 87, 2013
4M6K
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BU of 4m6k by Molmil
Crystal structure of human dihydrofolate reductase (DHFR) bound to NADP+ and folate
Descriptor: Dihydrofolate reductase, FOLIC ACID, GLYCEROL, ...
Authors:Bhabha, G, Ekiert, D.C, Wright, P.E, Wilson, I.A.
Deposit date:2013-08-09
Release date:2013-09-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.396 Å)
Cite:Divergent evolution of protein conformational dynamics in dihydrofolate reductase.
Nat.Struct.Mol.Biol., 20, 2013
4MHH
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BU of 4mhh by Molmil
Crystal structure of Fab H5M9 in complex with influenza virus hemagglutinin from A/Viet Nam/1203/2004 (H5N1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H5M9 antibody, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-08-29
Release date:2013-10-02
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.564 Å)
Cite:A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by an Antibody against the A/Goose/Guangdong/1/96 Hemagglutinin.
J.Virol., 87, 2013
2ERJ
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BU of 2erj by Molmil
Crystal structure of the heterotrimeric interleukin-2 receptor in complex with interleukin-2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Debler, E.W, Stauber, D.J, Wilson, I.A.
Deposit date:2005-10-25
Release date:2006-02-21
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of the IL-2 signaling complex: Paradigm for a heterotrimeric cytokine receptor.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2FK0
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BU of 2fk0 by Molmil
Crystal Structure of a H5N1 influenza virus hemagglutinin.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin
Authors:Stevens, J, Wilson, I.A.
Deposit date:2006-01-03
Release date:2006-05-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure and Receptor Specificity of the Hemagglutinin from an H5N1 Influenza Virus.
Science, 312, 2006
2G2R
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BU of 2g2r by Molmil
Green-fluorescent antibody 11G10 in complex with its hapten (nitro-stilbene derivative)
Descriptor: Green-fluorescent antibody (11G10)-heavy chain, Green-fluorescent antibody (11G10)-light chain, N-(TRANS-4'-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC ACID, ...
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2006-02-16
Release date:2006-12-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The Effects of Antibodies on Stilbene Excited-State Energetics.
Angew.Chem.Int.Ed.Engl., 45, 2006
2GJZ
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BU of 2gjz by Molmil
Structure of Catalytic Elimination Antibody 13G5 from a crystal in space group P2(1)
Descriptor: Catalytic elimination antibody 13G5 heavy chain, Catalytic elimination antibody 13G5 light chain, ZINC ION
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2006-03-31
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Bifunctional Catalysis of Proton Transfer at an Antibody Active Site.
J.Am.Chem.Soc., 129, 2007
2GK0
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BU of 2gk0 by Molmil
Structure of Catalytic Elimination Antibody 13G5 from a twinned crystal in space group C2
Descriptor: Catalytic elimination antibody 13G5 heavy chain, Catalytic elimination antibody 13G5 light chain
Authors:Debler, E.W, Wilson, I.A.
Deposit date:2006-03-31
Release date:2007-02-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Bifunctional Catalysis of Proton Transfer at an Antibody Active Site.
J.Am.Chem.Soc., 129, 2007
2FL5
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BU of 2fl5 by Molmil
Cofactor-containing antibodies: Crystal structure of the original yellow antibody
Descriptor: Immunoglobulin Igg1 Heavy chain, Immunoglobulin Igg1 Lambda Light Chain, RIBOFLAVIN
Authors:Zhu, X, Wilson, I.A.
Deposit date:2006-01-05
Release date:2006-02-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:Cofactor-containing antibodies: Crystal structure of the original yellow antibody.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2I27
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BU of 2i27 by Molmil
Crystal Structure Analysis of the Nurse Shark New Antigen Receptor Ancestral variable domain
Descriptor: New Antigen Receptor Ancestral
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2006-08-15
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding.
J.Mol.Biol., 367, 2007
2I24
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BU of 2i24 by Molmil
Crystal structure analysis of the nurse shark New Antigen Receptor PBLA8 variable domain
Descriptor: CHLORIDE ION, New Antigen Receptor PBLA8
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2006-08-15
Release date:2007-03-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding
J.Mol.Biol., 367, 2007
2I26
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BU of 2i26 by Molmil
Crystal structure analysis of the nurse shark new antigen receptor ancestral variable domain in complex with lysozyme
Descriptor: Lysozyme C, New Antigen Receptor Ancestral, SULFATE ION
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2006-08-15
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding.
J.Mol.Biol., 367, 2007
2I25
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BU of 2i25 by Molmil
Crystal structure analysis of the nurse shark New antigen Receptor PBLA8 variable domain in complex with lysozyme
Descriptor: Lysozyme C, New Antigen Receptor PBLA8
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2006-08-15
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding
J.Mol.Biol., 367, 2007
4NHC
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BU of 4nhc by Molmil
Crystal structure of the HIV-1 neutralizing antibody 4E10 Fab fragment in complex with a hydrocarbon-stapled peptide containing the 4e10 epitope on gp41.
Descriptor: FAB HEAVY CHAIN, FAB LIGHT CHAIN, MODIFIED FRAGMENT OF HIV GLYCOPROTEIN (GP41), ...
Authors:Irimia, A, Wilson, I.A.
Deposit date:2013-11-04
Release date:2014-12-03
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.912 Å)
Cite:Stapled HIV-1 peptides recapitulate antigenic structures and engage broadly neutralizing antibodies.
Nat.Struct.Mol.Biol., 21, 2014
4NJA
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BU of 4nja by Molmil
Crystal structure of Fab 6C8 in complex with MPTS
Descriptor: 6C8 heavy chain, 6C8 light chain, 8-methoxypyrene-1,3,6-trisulfonic acid, ...
Authors:Stanfield, R.L, Romesberg, F.E, Zimmermann, J, Wilson, I.A.
Deposit date:2013-11-08
Release date:2014-11-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Adaptive Mutations Alter Antibody Structure and Dynamics during Affinity Maturation.
Biochemistry, 54, 2015
4NUG
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BU of 4nug by Molmil
Crystal structure of HIV-1 broadly neutralizing antibody PGT151
Descriptor: HEXAETHYLENE GLYCOL, PGT151 heavy chain, PGT151 light chain
Authors:Blattner, C, Wilson, I.A.
Deposit date:2013-12-03
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8617 Å)
Cite:Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers.
Immunity, 40, 2014
4NM8
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BU of 4nm8 by Molmil
Crystal structure of broadly neutralizing antibody CR8043 bound to H3 influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8043, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-11-14
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.0041 Å)
Cite:A common solution to group 2 influenza virus neutralization.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NZT
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BU of 4nzt by Molmil
Crystal structure of the antibody-binding region of Protein M (Protein M TD) in complex with anti-infleunza hemagglutinin antibody CR9114 Fab
Descriptor: CR9114 heavy chain, CR9114 light chain, Protein M TD
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-12-12
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union.
Science, 343, 2014
4NM4
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BU of 4nm4 by Molmil
Crystal structure of broadly neutralizing antibody CR8043
Descriptor: Antibody CR8043, Heavy Chain, Light Chain, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-11-14
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:A common solution to group 2 influenza virus neutralization.
Proc.Natl.Acad.Sci.USA, 111, 2014
4NUJ
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BU of 4nuj by Molmil
Crystal structure of HIV-1 broadly neutralizing antibody PGT152
Descriptor: PGT152 heavy chain, PGT152 light chain
Authors:Blattner, C, Wilson, I.A.
Deposit date:2013-12-03
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.827 Å)
Cite:Structural Delineation of a Quaternary, Cleavage-Dependent Epitope at the gp41-gp120 Interface on Intact HIV-1 Env Trimers.
Immunity, 40, 2014
4O58
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BU of 4o58 by Molmil
Crystal structure of broadly neutralizing antibody F045-092 in complex with A/Victoria/3/1975 (H3N2) influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-12-19
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7501 Å)
Cite:Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014
4NZU
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BU of 4nzu by Molmil
Crystal structure of the primary monoclonal antibody 13PL Fab' from a multiple myeloma patient
Descriptor: 13PL heavy chain, 13PL light chain, ACETATE ION, ...
Authors:Zhu, X, Wilson, I.A.
Deposit date:2013-12-12
Release date:2014-02-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union.
Science, 343, 2014
4NWT
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BU of 4nwt by Molmil
Crystal structure of the anti-human NGF Fab APE1531
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, APE1531 Ab Fab heavy chain, ...
Authors:Verdino, P, Stanfield, R.L, Wilson, I.A.
Deposit date:2013-12-06
Release date:2014-10-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Nucleotide insertions and deletions complement point mutations to massively expand the diversity created by somatic hypermutation of antibodies.
J.Biol.Chem., 289, 2014
4O5L
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BU of 4o5l by Molmil
Crystal structure of broadly neutralizing antibody F045-092
Descriptor: Fab F045-092 heavy chain, Fab F045-092 light chain, PHOSPHATE ION
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-12-19
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5045 Å)
Cite:Receptor mimicry by antibody F045-092 facilitates universal binding to the H3 subtype of influenza virus.
Nat Commun, 5, 2014

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數據於2024-06-26公開中

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