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1CVA
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BU of 1cva by Molmil
STRUCTURAL AND FUNCTIONAL IMPORTANCE OF A CONSERVED HYDROGEN BOND NETWORK IN HUMAN CARBONIC ANHYDRASE II
Descriptor: AZIDE ION, CARBONIC ANHYDRASE II, ZINC ION
Authors:Ippolito, J.A, Christianson, D.W.
Deposit date:1993-02-04
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and functional importance of a conserved hydrogen bond network in human carbonic anhydrase II.
J.Biol.Chem., 268, 1993
1DMY
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BU of 1dmy by Molmil
COMPLEX BETWEEN MURINE MITOCHONDRIAL CARBONIC ANYHDRASE V AND THE TRANSITION STATE ANALOGUE ACETAZOLAMIDE
Descriptor: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, MURINE CARBONIC ANHYDRASE V, ZINC ION
Authors:Boriack-Sjodin, P.A, Christianson, D.W.
Deposit date:1995-10-04
Release date:1996-04-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure determination of murine mitochondrial carbonic anhydrase V at 2.45-A resolution: implications for catalytic proton transfer and inhibitor design.
Proc.Natl.Acad.Sci.USA, 92, 1995
1CVB
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BU of 1cvb by Molmil
STRUCTURAL AND FUNCTIONAL IMPORTANCE OF A CONSERVED HYDROGEN BOND NETWORK IN HUMAN CARBONIC ANHYDRASE II
Descriptor: CARBONIC ANHYDRASE II, SULFATE ION, ZINC ION
Authors:Ippolito, J.A, Christianson, D.W.
Deposit date:1993-02-04
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional importance of a conserved hydrogen bond network in human carbonic anhydrase II.
J.Biol.Chem., 268, 1993
1CPS
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BU of 1cps by Molmil
STRUCTURAL COMPARISON OF SULFODIIMINE AND SULFONAMIDE INHIBITORS IN THEIR COMPLEXES WITH ZINC ENZYMES
Descriptor: CARBOXYPEPTIDASE A, S-(2-CARBOXY-3-PHENYLPROPYL)THIODIIMINE-S-METHANE, ZINC ION
Authors:Cappalonga, A.M, Alexander, R.S, Christianson, D.W.
Deposit date:1992-02-18
Release date:1993-10-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural comparison of sulfodiimine and sulfonamide inhibitors in their complexes with zinc enzymes.
J.Biol.Chem., 267, 1992
1CNX
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BU of 1cnx by Molmil
SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS
Descriptor: AMINODI(ETHYLOXY)ETHYLAMINOCARBONYLBENZENESULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ...
Authors:Boriack, P.A, Christianson, D.W.
Deposit date:1995-07-21
Release date:1995-11-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase II influence inhibitor binding constants.
J.Med.Chem., 38, 1995
1CR6
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BU of 1cr6 by Molmil
CRYSTAL STRUCTURE OF MURINE SOLUBLE EPOXIDE HYDROLASE COMPLEXED WITH CPU INHIBITOR
Descriptor: EPOXIDE HYDROLASE, N-CYCLOHEXYL-N'-(PROPYL)PHENYL UREA
Authors:Argiriadi, M.A, Morisseau, C, Hammock, B.D, Christianson, D.W.
Deposit date:1999-08-13
Release date:1999-11-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase.
Proc.Natl.Acad.Sci.USA, 96, 1999
1CVC
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BU of 1cvc by Molmil
REDESIGNING THE ZINC BINDING SITE OF HUMAN CARBONIC ANHYDRASE II: STRUCTURE OF A HIS2ASP-ZN2+ METAL COORDINATION POLYHEDRON
Descriptor: CARBONIC ANHYDRASE II, ZINC ION
Authors:Ippolito, J.A, Christianson, D.W.
Deposit date:1993-09-22
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:REDESIGNING THE ZINC-BINDING SITE OF HUMAN CARBONIC ANHYDRASE-II - STRUCTURE OF A HIS2ASP-ZN2+ METAL COORDINATION POLYHEDRON.
J.Am.Chem.Soc., 115, 1993
1CIN
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BU of 1cin by Molmil
THE POSITIONS OF HIS-64 AND A BOUND WATER IN HUMAN CARBONIC ANHYDRASE II UPON BINDING THREE STRUCTURALLY RELATED INHIBITORS
Descriptor: (4S-TRANS)-4-(METHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, CARBONIC ANHYDRASE II, METHYL MERCURY ION, ...
Authors:Smith, G.M, Alexander, R.S, Christianson, D.W, Mckeever, B.M, Ponticello, G.S, Springer, J.P, Randall, W.C, Baldwin, J.J, Habecker, C.N.
Deposit date:1993-10-20
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors.
Protein Sci., 3, 1994
1CNY
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BU of 1cny by Molmil
SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS
Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, PHENYLALANYLAMINODI(ETHYLOXY)ETHYL BENZENESULFONAMIDEAMINOCARBONYLBENZENESULFONAMIDE, ...
Authors:Boriack, P.A, Christianson, D.W.
Deposit date:1995-07-21
Release date:1995-11-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase II influence inhibitor binding constants.
J.Med.Chem., 38, 1995
1CNG
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BU of 1cng by Molmil
X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE
Descriptor: CARBONIC ANHYDRASE II, CHLORIDE ION, ZINC ION
Authors:Lesburg, C.A, Christianson, D.W.
Deposit date:1995-04-03
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site
J.Am.Chem.Soc., 117, 1995
1CNK
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BU of 1cnk by Molmil
X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE
Descriptor: CARBONIC ANHYDRASE II, SULFATE ION, ZINC ION
Authors:Lesburg, C.A, Christianson, D.W.
Deposit date:1995-04-03
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site
J.Am.Chem.Soc., 117, 1995
1CIL
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BU of 1cil by Molmil
THE POSITIONS OF HIS-64 AND A BOUND WATER IN HUMAN CARBONIC ANHYDRASE II UPON BINDING THREE STRUCTURALLY RELATED INHIBITORS
Descriptor: (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, CARBONIC ANHYDRASE II, ZINC ION
Authors:Smith, G.M, Alexander, R.S, Christianson, D.W, Mckeever, B.M, Ponticello, G.S, Springer, J.P, Randall, W.C, Baldwin, J.J, Habecker, C.N.
Deposit date:1993-10-20
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors.
Protein Sci., 3, 1994
1CNH
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BU of 1cnh by Molmil
X-RAY CRYSTALLOGRAPHIC STUDIES OF ENGINEERED HYDROGEN BOND NETWORKS IN A PROTEIN-ZINC BINDING SITE
Descriptor: CARBONIC ANHYDRASE II, ZINC ION
Authors:Lesburg, C.A, Christianson, D.W.
Deposit date:1995-04-03
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:X-Ray Crystallographic Studies of Engineered Hydrogen Bond Networks in a Protein-Zinc Binding Site
J.Am.Chem.Soc., 117, 1995
1FQN
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BU of 1fqn by Molmil
X-RAY CRYSTAL STRUCTURE OF METAL-FREE F93I/F95M/W97V CARBONIC ANHYDRASE (CAII) VARIANT
Descriptor: CARBONIC ANHYDRASE
Authors:Cox, J.D, Hunt, J.A, Compher, K.M, Fierke, C.A, Christianson, D.W.
Deposit date:2000-09-06
Release date:2001-01-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II.
Biochemistry, 39, 2000
1FQM
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BU of 1fqm by Molmil
X-RAY CRYSTAL STRUCTURE OF ZINC-BOUND F93I/F95M/W97V CARBONIC ANHYDRASE (CAII) VARIANT
Descriptor: CARBONIC ANHYDRASE, MERCURY (II) ION, ZINC ION
Authors:Cox, J.D, Hunt, J.A, Compher, K.M, Fierke, C.A, Christianson, D.W.
Deposit date:2000-09-06
Release date:2001-01-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II.
Biochemistry, 39, 2000
1FSQ
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BU of 1fsq by Molmil
X-RAY CRYSTAL STRUCTURE OF COBALT-BOUND F93S/F95L/W97M CARBONIC ANHYDRASE (CAII) VARIANT
Descriptor: CARBONIC ANHYDRASE II, COBALT (II) ION
Authors:Cox, J.D, Hunt, J.A, Compher, K.M, Fierke, C.A, Christianson, D.W.
Deposit date:2000-09-11
Release date:2001-01-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II.
Biochemistry, 39, 2000
1D3V
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BU of 1d3v by Molmil
CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH 2(S)-AMINO-6-BORONOHEXANOIC ACID, AN L-ARGININE ANALOG
Descriptor: 2(S)-AMINO-6-BORONOHEXANOIC ACID, MANGANESE (II) ION, PROTEIN (ARGINASE)
Authors:Cox, J.D, Kim, N.N, Traish, A.M, Christianson, D.W.
Deposit date:1999-10-01
Release date:1999-11-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Arginase-boronic acid complex highlights a physiological role in erectile function.
Nat.Struct.Biol., 6, 1999
1FR4
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BU of 1fr4 by Molmil
X-RAY CRYSTAL STRUCTURE OF COPPER-BOUND F93I/F95M/W97V CARBONIC ANHYDRASE (CAII) VARIANT
Descriptor: CARBONIC ANHYDRASE II, COPPER (II) ION, SULFATE ION
Authors:Cox, J.D, Hunt, J.A, Compher, K.M, Fierke, C.A, Christianson, D.W.
Deposit date:2000-09-07
Release date:2001-01-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II.
Biochemistry, 39, 2000
1FSN
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BU of 1fsn by Molmil
X-RAY CRYSTAL STRUCTURE OF METAL-FREE F93S/F95L/W97M CARBONIC ANHYDRASE (CAII) VARIANT
Descriptor: CARBONIC ANHYDRASE II
Authors:Cox, J.D, Hunt, J.A, Compher, K.M, Fierke, C.A, Christianson, D.W.
Deposit date:2000-09-11
Release date:2001-01-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II.
Biochemistry, 39, 2000
1CNW
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BU of 1cnw by Molmil
SECONDARY INTERACTIONS SIGNIFICANTLY REMOVED FROM THE SULFONAMIDE BINDING POCKET OF CARBONIC ANHYDRASE II INFLUENCE BINDING CONSTANTS
Descriptor: AMINOMETHYLENECARBONYLAMINODI(ETHYLOXY)ETHYLAMINOCARBONYLBENZENESULFONAMIDE, CARBONIC ANHYDRASE II, MERCURY (II) ION, ...
Authors:Boriack, P.A, Christianson, D.W.
Deposit date:1995-07-21
Release date:1995-11-14
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase II influence inhibitor binding constants.
J.Med.Chem., 38, 1995
1CQZ
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BU of 1cqz by Molmil
CRYSTAL STRUCTURE OF MURINE SOLUBLE EPOXIDE HYDROLASE.
Descriptor: EPOXIDE HYDROLASE
Authors:Argiriadi, M.A, Morisseau, C, Hammock, B.D, Christianson, D.W.
Deposit date:1999-08-12
Release date:1999-11-19
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase.
Proc.Natl.Acad.Sci.USA, 96, 1999
1DGP
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BU of 1dgp by Molmil
ARISTOLOCHENE SYNTHASE FARNESOL COMPLEX
Descriptor: (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, (2Z,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, ARISTOLOCHENE SYNTHASE
Authors:Caruthers, J.M, Kang, I, Cane, D.E, Christianson, D.W.
Deposit date:1999-11-24
Release date:2001-02-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure determination of aristolochene synthase from the blue cheese mold, Penicillium roqueforti.
J.Biol.Chem., 275, 2000
1FQR
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BU of 1fqr by Molmil
X-RAY CRYSTAL STRUCTURE OF COBALT-BOUND F93I/F95M/W97V CARBONIC ANHYDRASE (CAII) VARIANT
Descriptor: CARBONIC ANHYDRASE, COBALT (II) ION
Authors:Cox, J.D, Hunt, J.A, Compher, K.M, Fierke, C.A, Christianson, D.W.
Deposit date:2000-09-06
Release date:2001-01-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II.
Biochemistry, 39, 2000
1FR7
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BU of 1fr7 by Molmil
X-RAY CRYSTAL STRUCTURE OF ZINC-BOUND F93S/F95L/W97M CARBONIC ANHYDRASE (CAII) VARIANT
Descriptor: CARBONIC ANHYDRASE II, ZINC ION
Authors:Cox, J.D, Hunt, J.A, Compher, K.M, Fierke, C.A, Christianson, D.W.
Deposit date:2000-09-07
Release date:2001-01-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II.
Biochemistry, 39, 2000
1FSR
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BU of 1fsr by Molmil
X-RAY CRYSTAL STRUCTURE OF COPPER-BOUND F93S/F95L/W97M CARBONIC ANHYDRASE (CAII) VARIANT
Descriptor: CARBONIC ANHYDRASE II, COPPER (II) ION
Authors:Cox, J.D, Hunt, J.A, Compher, K.M, Fierke, C.A, Christianson, D.W.
Deposit date:2000-09-11
Release date:2001-01-17
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural influence of hydrophobic core residues on metal binding and specificity in carbonic anhydrase II.
Biochemistry, 39, 2000

238582

數據於2025-07-09公開中

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