5XIK
 
 | | Crystal Structure of Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with tetrahydro quinazolinone febrifugine | | Descriptor: | 3-[2-oxidanylidene-3-[(2R,3R)-3-oxidanylpiperidin-2-yl]propyl]-5,6,7,8-tetrahydroquinazolin-4-one, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Jain, V, Manickam, Y, Sharma, A. | | Deposit date: | 2017-04-26 | | Release date: | 2018-03-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
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5XIP
 | | Crystal Structure of Eimeria tenella Prolyl-tRNA Synthetase (EtPRS) in complex with Halofuginone | | Descriptor: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Jain, V, Manickam, Y, Sharma, A. | | Deposit date: | 2017-04-26 | | Release date: | 2018-03-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
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2ZVU
 | | Crystal structure of rat heme oxygenase-1 in complex with ferrous verdoheme | | Descriptor: | 5-OXA-PROTOPORPHYRIN IX CONTAINING FE, FORMIC ACID, Heme oxygenase 1 | | Authors: | Sato, H, Sugishima, M, Fukuyama, K, Noguchi, M. | | Deposit date: | 2008-11-21 | | Release date: | 2009-02-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of rat haem oxygenase-1 in complex with ferrous verdohaem: presence of a hydrogen-bond network on the distal side
Biochem.J., 419, 2009
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5XIQ
 | | Crystal Structure of Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with Halofuginone | | Descriptor: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Jain, V, Manickam, Y, Sharma, A. | | Deposit date: | 2017-04-26 | | Release date: | 2018-03-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
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5XII
 | | Crystal Structure of Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with inhibitor 6 | | Descriptor: | 1,2-ETHANEDIOL, 6-chloranyl-7-fluoranyl-3-[3-[(2R)-3-oxidanylidenepiperidin-2-yl]propyl]quinazolin-4-one, CHLORIDE ION, ... | | Authors: | Jain, V, Manickam, Y, Sharma, A. | | Deposit date: | 2017-04-26 | | Release date: | 2018-03-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
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3A2P
 | | Structure of 6-aminohexanoate cyclic dimer hydrolase | | Descriptor: | 6-aminohexanoate-cyclic-dimer hydrolase, GLYCEROL | | Authors: | Shibata, N. | | Deposit date: | 2009-05-26 | | Release date: | 2009-11-03 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | X-ray crystallographic analysis of the 6-aminohexanoate cyclic dimer hydrolase: catalytic mechanism and evolution of an enzyme responsible for nylon-6 byproduct degradation
J.Biol.Chem., 285, 2010
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3A4E
 | | Crystal structure of Human Transthyretin (E54G) | | Descriptor: | GLYCEROL, SULFATE ION, Transthyretin | | Authors: | Miyata, M, Sato, T, Nakamura, T, Ikemizu, S, Yamagata, Y, Kai, H. | | Deposit date: | 2009-07-06 | | Release date: | 2009-12-22 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding
Biochemistry, 49, 2010
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2ZXX
 | | Crystal structure of Cdt1/geminin complex | | Descriptor: | DNA replication factor Cdt1, Geminin | | Authors: | Cho, Y, Lee, C, Hong, B.S, Choi, J.M. | | Deposit date: | 2009-01-08 | | Release date: | 2009-02-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for inhibition of the replication licensing factor Cdt1 by geminin
Nature, 430, 2004
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3A4D
 | | Crystal structure of Human Transthyretin (wild-type) | | Descriptor: | GLYCEROL, SULFATE ION, Transthyretin | | Authors: | Miyata, M. | | Deposit date: | 2009-07-06 | | Release date: | 2009-12-22 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Role of the Glutamic Acid 54 Residue in Transthyretin Stability and Thyroxine Binding
Biochemistry, 2009
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2EC7
 | | Solution Structure of Human Immunodificiency Virus Type-2 Nucleocapsid Protein | | Descriptor: | Gag polyprotein (Pr55Gag), ZINC ION | | Authors: | Matsui, T, Kodera, Y, Tanaka, T, Endoh, H, Tanaka, H, Miyauchi, E, Komatsu, H, Kohno, T, Maeda, T. | | Deposit date: | 2007-02-10 | | Release date: | 2008-02-19 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The RNA recognition mechanism of human immunodeficiency virus (HIV) type 2 NCp8 is different from that of HIV-1 NCp7
Biochemistry, 48, 2009
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2D7T
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3AW5
 | | Structure of a multicopper oxidase from the hyperthermophilic archaeon Pyrobaculum aerophilum | | Descriptor: | ACETATE ION, COPPER (II) ION, CU-O-CU LINKAGE, ... | | Authors: | Sakuraba, H, Ohshima, T, Yoneda, K. | | Deposit date: | 2011-03-10 | | Release date: | 2011-06-08 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of a multicopper oxidase from the hyperthermophilic archaeon Pyrobaculum aerophilum
Acta Crystallogr.,Sect.F, 67, 2011
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3AW0
 | | Structure of SARS 3CL protease with peptidic aldehyde inhibitor | | Descriptor: | 3C-Like Proteinase, peptide ACE-SER-ALA-VAL-LEU-HIS-H | | Authors: | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | | Deposit date: | 2011-03-09 | | Release date: | 2011-12-14 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors.
J.Med.Chem., 54, 2011
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3AW1
 | | Structure of SARS 3CL protease auto-proteolysis resistant mutant in the absent of inhibitor | | Descriptor: | 3C-Like Proteinase | | Authors: | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | | Deposit date: | 2011-03-09 | | Release date: | 2011-12-14 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors.
J.Med.Chem., 54, 2011
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3ATW
 | | Structure-Based Design, Synthesis, Evaluation of Peptide-mimetic SARS 3CL Protease Inhibitors | | Descriptor: | 3C-Like Proteinase, peptide ACE-THR-VAL-ALC-HIS-H | | Authors: | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | | Deposit date: | 2011-01-20 | | Release date: | 2011-12-14 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors.
J.Med.Chem., 54, 2011
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3AVZ
 | | Structure of SARS 3CL protease with peptidic aldehyde inhibitor containing cyclohexyl side chain | | Descriptor: | 3C-Like Proteinase, peptide ACE-SER-ALA-VAL-ALC-HIS-H | | Authors: | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | | Deposit date: | 2011-03-09 | | Release date: | 2011-12-14 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.46 Å) | | Cite: | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors.
J.Med.Chem., 54, 2011
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5XRZ
 | | Structure of a ssDNA bound to the inner DNA binding site of RAD52 | | Descriptor: | DNA repair protein RAD52 homolog, POTASSIUM ION, ssDNA (40-MER) | | Authors: | Saotome, M, Saito, K, Yasuda, T, Sugiyama, S, Kurumizaka, H, Kagawa, W. | | Deposit date: | 2017-06-11 | | Release date: | 2018-04-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structural Basis of Homology-Directed DNA Repair Mediated by RAD52
iScience, 3, 2018
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3AL9
 | | Mouse Plexin A2 extracellular domain | | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A2 | | Authors: | Nogi, T, Yasui, N, Mihara, E, Takagi, J. | | Deposit date: | 2010-07-28 | | Release date: | 2010-10-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for semaphorin signalling through the plexin receptor.
Nature, 467, 2010
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5XS0
 | | Structure of a ssDNA bound to the outer DNA binding site of RAD52 | | Descriptor: | DNA repair protein RAD52 homolog, ssDNA (5'-D(*CP*CP*CP*CP*CP*C)-3'), ssDNA (5'-D(*CP*CP*CP*CP*CP*CP*CP*C)-3'), ... | | Authors: | Saotome, M, Saito, K, Yasuda, T, Sugiyama, S, Kurumizaka, H, Kagawa, W. | | Deposit date: | 2017-06-11 | | Release date: | 2018-04-25 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Basis of Homology-Directed DNA Repair Mediated by RAD52
iScience, 3, 2018
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5ZT8
 | | SirB from Bacillus subtilis | | Descriptor: | Sirohydrochlorin ferrochelatase | | Authors: | Fujishiro, T. | | Deposit date: | 2018-05-02 | | Release date: | 2019-02-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of sirohydrochlorin ferrochelatase SirB: the last of the structures of the class II chelatase family.
Dalton Trans, 48, 2019
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3AFC
 | | Mouse Semaphorin 6A extracellular domain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Semaphorin-6A | | Authors: | Yasui, N, Nogi, T, Mihara, E, Takagi, J. | | Deposit date: | 2010-02-26 | | Release date: | 2010-10-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for semaphorin signalling through the plexin receptor.
Nature, 467, 2010
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3AL8
 | | Plexin A2 / Semaphorin 6A complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-A2, ... | | Authors: | Nogi, T, Yasui, N, Mihara, E, Takagi, J. | | Deposit date: | 2010-07-28 | | Release date: | 2010-10-06 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Structural basis for semaphorin signalling through the plexin receptor.
Nature, 467, 2010
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5ZT7
 | | SirB from Bacillus subtilis with Co2+ | | Descriptor: | COBALT (II) ION, Sirohydrochlorin ferrochelatase | | Authors: | Fujishiro, T. | | Deposit date: | 2018-05-02 | | Release date: | 2019-02-27 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | Structure of sirohydrochlorin ferrochelatase SirB: the last of the structures of the class II chelatase family.
Dalton Trans, 48, 2019
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2CB3
 | | Crystal structure of peptidoglycan recognition protein-LE in complex with tracheal cytotoxin (monomeric diaminopimelic acid-type peptidoglycan) | | Descriptor: | GLCNAC(BETA1-4)-MURNAC(1,6-ANHYDRO)-L-ALA-GAMMA-D-GLU-MESO-A2PM-D-ALA, GLYCEROL, PEPTIDOGLYCAN-RECOGNITION PROTEIN-LE | | Authors: | Lim, J.-H, Kim, M.-S, Oh, B.-H. | | Deposit date: | 2005-12-29 | | Release date: | 2006-01-26 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Basis for Preferential Recognition of Diaminopimelic Acid-Type Peptidoglycan by a Subset of Peptidoglycan Recognition Proteins
J.Biol.Chem., 281, 2006
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3A5R
 | | Benzalacetone synthase from Rheum palmatum complexed with 4-coumaroyl-primed monoketide intermediate | | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Benzalacetone synthase | | Authors: | Morita, H, Kato, R, Abe, I, Sugio, S, Kohno, T. | | Deposit date: | 2009-08-10 | | Release date: | 2010-01-26 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | A structure-based mechanism for benzalacetone synthase from Rheum palmatum
Proc.Natl.Acad.Sci.USA, 107, 2010
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