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7S9B
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BU of 7s9b by Molmil
Cryo-EM Structure of dolphin Prestin: Sensor Down I (Expanded) state
Descriptor: Prestin
Authors:Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E.
Deposit date:2021-09-20
Release date:2021-11-03
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:The conformational cycle of prestin underlies outer-hair cell electromotility.
Nature, 600, 2021
3OR6
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BU of 3or6 by Molmil
On the structural basis of modal gating behavior in K+channels - E71Q
Descriptor: POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ...
Authors:Chakrapani, S, Cordero-Morales, J.F, Jogini, V, Perozo, E.
Deposit date:2010-09-06
Release date:2011-01-05
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:On the structural basis of modal gating behavior in K(+) channels.
Nat.Struct.Mol.Biol., 18, 2011
3PJS
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BU of 3pjs by Molmil
Mechanism of Activation Gating in the Full-Length KcsA K+ Channel
Descriptor: FAB heavy chain, FAB light chain, Voltage-gated potassium channel
Authors:Uysal, S, Cuello, L.G, Kossiakoff, A, Perozo, E.
Deposit date:2010-11-10
Release date:2011-07-06
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Mechanism of activation gating in the full-length KcsA K+ channel.
Proc.Natl.Acad.Sci.USA, 108, 2011
3OR7
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BU of 3or7 by Molmil
On the structural basis of modal gating behavior in K+channels - E71I
Descriptor: POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ...
Authors:Chakrapani, S, Cordero-Morales, J.F, Jogini, V, Pan, A.C, Cortes, D.M, Roux, B, Perozo, E.
Deposit date:2010-09-06
Release date:2011-01-05
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:On the structural basis of modal gating behavior in K(+) channels.
Nat.Struct.Mol.Biol., 18, 2011
3EFD
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BU of 3efd by Molmil
The crystal structure of the cytoplasmic domain of KcsA
Descriptor: FabH, FabL, KcsA
Authors:Uysal, S, Vasquez, V, Tereshko, V, Esaki, K, Fellouse, F.A, Sidhu, S.S, Koide, S, Perozo, E, Kossiakoff, A.
Deposit date:2008-09-08
Release date:2009-04-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of full-length KcsA in its closed conformation.
Proc.Natl.Acad.Sci.USA, 106, 2009
3HPL
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BU of 3hpl by Molmil
KcsA E71H-F103A mutant in the closed state
Descriptor: Antibody Fab heavy chain, Antibody fab light chain, POTASSIUM ION, ...
Authors:Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E.
Deposit date:2009-06-04
Release date:2010-06-23
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for the coupling between activation and inactivation gates in K(+) channels.
Nature, 466, 2010
3EFF
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BU of 3eff by Molmil
The Crystal Structure of Full-Length KcsA in its Closed Conformation
Descriptor: FAB, Voltage-gated potassium channel
Authors:Uysal, S, Vasquez, V, Tereshko, T, Esaki, K, Fellouse, F.A, Sidhu, S.S, Koide, S, Perozo, E, Kossiakoff, A.
Deposit date:2008-09-08
Release date:2009-04-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystal structure of full-length KcsA in its closed conformation.
Proc.Natl.Acad.Sci.USA, 106, 2009
3FB5
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BU of 3fb5 by Molmil
KcsA potassium channel in the partially open state with 14.5 A opening at T112
Descriptor: POTASSIUM ION, Voltage-gated potassium channel, antibody Fab fragment heavy chain, ...
Authors:Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E.
Deposit date:2008-11-18
Release date:2010-05-19
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:KcsA potassium channel in the partially open state with 14.5 A opening at T112
TO BE PUBLISHED
3FB6
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BU of 3fb6 by Molmil
KcsA Potassium channel in the partially open state with 16 A opening at T112
Descriptor: POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ...
Authors:Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E.
Deposit date:2008-11-18
Release date:2010-05-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:KcsA Potassium channel in the partially open state with 16 A opening at T112
TO BE PUBLISHED
3FB7
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BU of 3fb7 by Molmil
Open KcsA potassium channel in the presence of Rb+ ion
Descriptor: RUBIDIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ...
Authors:Cuello, L.G, Jogini, V, Cortes, D.M, Pan, A.C, Gagnon, D.H, Cordero-Morales, J.F, Chakrapani, S, Roux, B, Perozo, E.
Deposit date:2008-11-18
Release date:2010-07-14
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Open KcsA potassium channel in the presence of Rb+ ion
TO BE PUBLISHED
3F7Y
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BU of 3f7y by Molmil
KcsA Potassium channel in the partially open state with 17 A opening at T112
Descriptor: POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ...
Authors:Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E.
Deposit date:2008-11-10
Release date:2010-05-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:KcsA Potassium channel in the partially open state with 17 A opening at T112
TO BE PUBLISHED
3F5W
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BU of 3f5w by Molmil
KcsA Potassium channel in the open-inactivated state with 32 A opening at T112
Descriptor: Antibody heavy chain, Antibody light chain, POTASSIUM ION, ...
Authors:Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E.
Deposit date:2008-11-04
Release date:2010-05-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:KcsA Potassium channel in the open-inactivated state with 32 A opening at T112
TO BE PUBLISHED
3JCF
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BU of 3jcf by Molmil
Cryo-EM structure of the magnesium channel CorA in the closed symmetric magnesium-bound state
Descriptor: MAGNESIUM ION, Magnesium transport protein CorA
Authors:Matthies, D, Perozo, E, Subramaniam, S.
Deposit date:2015-12-11
Release date:2016-02-17
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
Cell(Cambridge,Mass.), 164, 2016
3FB8
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BU of 3fb8 by Molmil
KcsA Potassium channel in the open-conductive state with 20 A opening at T112 in the presence of Rb+ ion
Descriptor: RUBIDIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ...
Authors:Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E.
Deposit date:2008-11-18
Release date:2010-05-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:KcsA Potassium channel in the open-conductive state with 20 A opening at T112 in the presence of Rb+ ion
TO BE PUBLISHED
3F7V
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BU of 3f7v by Molmil
KcsA Potassium channel in the open-inactivated state with 23 A opening at T112
Descriptor: POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment Heavy chain, ...
Authors:Cuello, L.G, Jogini, V, Cortes, D.M, Perozo, E.
Deposit date:2008-11-10
Release date:2010-05-19
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:KcsA Potassium channel in the open-inactivated state with 23 A opening at T112
TO BE PUBLISHED
3JCH
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BU of 3jch by Molmil
Cryo-EM structure of the magnesium channel CorA in the magnesium-free, asymmetric open state II
Descriptor: Magnesium transport protein CorA
Authors:Matthies, D, Perozo, E, Subramaniam, S.
Deposit date:2015-12-11
Release date:2016-02-17
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.06 Å)
Cite:Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
Cell(Cambridge,Mass.), 164, 2016
8SLB
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BU of 8slb by Molmil
X-ray structure of CorA N-terminal domain in complex with conformation-specific synthetic antibody C12
Descriptor: CHLORIDE ION, Cobalt/magnesium transport protein CorA, sAB C12 Heavy Chain, ...
Authors:Dominik, P.K, Erramilli, S.K, Reddy, B.G, Kossiakoff, A.A.
Deposit date:2023-04-21
Release date:2023-06-07
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA.
J.Mol.Biol., 435, 2023
9CHP
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BU of 9chp by Molmil
Cryo-EM structure of the human ether-a-go-go related K+ channel (hERG) in 300 mM K+
Descriptor: Potassium voltage-gated channel subfamily H member 2
Authors:Lau, C.H.Y, Hunter, M.J, Vandenberg, J.I.
Deposit date:2024-07-01
Release date:2024-08-21
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Potassium dependent structural changes in the selectivity filter of HERG potassium channels.
Nat Commun, 15, 2024
9CHQ
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BU of 9chq by Molmil
Cryo-EM structure of the human ether-a-go-go related K+ channel (hERG) in 3 mM K+
Descriptor: Potassium voltage-gated channel subfamily H member 2
Authors:Lau, C.H.Y, Hunter, M.J, Vandenberg, J.I.
Deposit date:2024-07-01
Release date:2024-08-21
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Potassium dependent structural changes in the selectivity filter of HERG potassium channels.
Nat Commun, 15, 2024
9CHS
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BU of 9chs by Molmil
Cryo-EM structure of the human ether-a-go-go related K+ channel (hERG) in 3 mM K+ without symmetry
Descriptor: Potassium voltage-gated channel subfamily H member 2
Authors:Lau, C.H.Y, Hunter, M.J, Vandenberg, J.I.
Deposit date:2024-07-01
Release date:2024-08-21
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Potassium dependent structural changes in the selectivity filter of HERG potassium channels.
Nat Commun, 15, 2024
9CHR
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BU of 9chr by Molmil
Cryo-EM structure of the human ether-a-go-go related K+ channel (hERG) in 300 mM K+ without symmetry
Descriptor: Potassium voltage-gated channel subfamily H member 2
Authors:Lau, C.H.Y, Hunter, M.J, Vandenberg, J.I.
Deposit date:2024-07-01
Release date:2024-08-21
Last modified:2024-09-11
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Potassium dependent structural changes in the selectivity filter of HERG potassium channels.
Nat Commun, 15, 2024
2KIR
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BU of 2kir by Molmil
Solution structure of a designer toxin, mokatoxin-1
Descriptor: Designer toxin
Authors:Biancalana, M, Koide, A, Takacs, Z, Goldstein, S, Koide, S.
Deposit date:2009-05-07
Release date:2009-12-29
Last modified:2024-10-09
Method:SOLUTION NMR
Cite:A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library.
Proc.Natl.Acad.Sci.USA, 106, 2009
3NWQ
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BU of 3nwq by Molmil
X-ray structure of ester chemical analogue [O-Ile50,O-Ile50']HIV-1 protease complexed with MVT-101
Descriptor: N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, protease
Authors:Torbeev, V.Y, Kent, S.B.H.
Deposit date:2010-07-10
Release date:2011-11-02
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Protein conformational dynamics in the mechanism of HIV-1 protease catalysis.
Proc.Natl.Acad.Sci.USA, 108, 2011
3NXE
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BU of 3nxe by Molmil
X-ray structure of ester chemical analogue 'covalent dimer' [Ile50,O-Ile50']HIV-1 protease complexed with MVT-101 inhibitor
Descriptor: N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, SULFATE ION, protease covalent dimer
Authors:Torbeev, V.Y, Kent, S.B.H.
Deposit date:2010-07-13
Release date:2011-11-02
Last modified:2012-12-12
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Protein conformational dynamics in the mechanism of HIV-1 protease catalysis.
Proc.Natl.Acad.Sci.USA, 108, 2011
4G7V
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BU of 4g7v by Molmil
Crystal structure of voltage sensing domain of Ci-VSP with fragment antibody (R217E, 2.5 A)
Descriptor: CHLORIDE ION, LAURYL DIMETHYLAMINE-N-OXIDE, SUCCINIC ACID, ...
Authors:Li, Q.
Deposit date:2012-07-20
Release date:2014-02-05
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain.
Nat. Struct. Mol. Biol., 21, 2014

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數據於2024-10-30公開中

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