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8VCJ
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BU of 8vcj by Molmil
CryoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 7:2:1 stoichiometry from E. coli Tn7 bound to ATPgS and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA, MAGNESIUM ION, ...
Authors:Shen, Y, Guarne, A.
Deposit date:2023-12-14
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Assembly of the Tn7 targeting complex by a regulated stepwise process.
Mol.Cell, 84, 2024
3FMT
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BU of 3fmt by Molmil
Crystal structure of SeqA bound to DNA
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 5'-D(*GP*AP*GP*TP*CP*GP*(6MA)P*TP*CP*GP*GP*CP*GP*GP*GP*(6MA)P*TP*CP*CP*TP*TP*A)-3', 5'-D(*TP*CP*TP*AP*AP*GP*GP*AP*TP*CP*CP*CP*GP*CP*CP*GP*AP*TP*CP*GP*AP*C)-3', ...
Authors:Chung, Y.S, Brendler, T, Austin, S, Guarne, A.
Deposit date:2008-12-22
Release date:2009-04-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.983 Å)
Cite:Structural insights into the cooperative binding of SeqA to a tandem GATC repeat
Nucleic Acids Res., 37, 2009
8GLU
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BU of 8glu by Molmil
CryoEM structure of TnsC(1-503) bound to TnsD(1-318) from E.coli Tn7
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Shen, Y, Guarne, A.
Deposit date:2023-03-23
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Assembly of the Tn7 targeting complex by a regulated stepwise process.
Mol.Cell, 84, 2024
8GLW
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BU of 8glw by Molmil
CryoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 7:2:1 stoichiometry from E. coli Tn7
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (50-MER), ...
Authors:Shen, Y, Guarne, A.
Deposit date:2023-03-23
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (3.51 Å)
Cite:Assembly of the Tn7 targeting complex by a regulated stepwise process.
Mol.Cell, 84, 2024
8GLX
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BU of 8glx by Molmil
CryoEM structure of the TnsC(1-503)-TnsD(1-318)-DNA complex in a 6:2:1 stoichiometry from E. coli Tn7
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, DNA (50-MER), ...
Authors:Shen, Y, Guarne, A.
Deposit date:2023-03-23
Release date:2024-07-31
Method:ELECTRON MICROSCOPY (3.88 Å)
Cite:Assembly of the Tn7 targeting complex by a regulated stepwise process.
Mol.Cell, 84, 2024
3OQ4
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BU of 3oq4 by Molmil
Crystal Structure of motif N of Saccharomyces cerevisiae Dbf4
Descriptor: DBF4
Authors:Matthews, L.A, Jones, D.R, Prasad, A.A, Duncker, B.P, Guarne, A.
Deposit date:2010-09-02
Release date:2011-09-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of Saccharomyces cerevisiae Dbf4-motif N
To be Published
3QBZ
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BU of 3qbz by Molmil
Crystal structure of the Rad53-recognition domain of Saccharomyces cerevisiae Dbf4
Descriptor: DDK kinase regulatory subunit DBF4, SULFATE ION
Authors:Matthews, L.A, Jones, D.R, Prasad, A.A, Duncker, B.P, Guarne, A.
Deposit date:2011-01-14
Release date:2011-12-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.692 Å)
Cite:Saccharomyces cerevisiae Dbf4 has unique fold necessary for interaction with Rad53 kinase.
J.Biol.Chem., 287, 2012
3OQ0
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BU of 3oq0 by Molmil
Crystal Structure of motif N of Saccharomyces cerevisiae Dbf4
Descriptor: DBF4
Authors:Matthews, L.A, Jones, D.R, Prasad, A.A, Duncker, B.P, Guarne, A.
Deposit date:2010-09-02
Release date:2011-09-07
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure of Saccharomyces cerevisiae Dbf4-motif N
To be Published
6PPF
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BU of 6ppf by Molmil
Bacterial 45SRbgA ribosomal particle class B
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Ortega, J, Seffouh, A, Jain, N, Jahagirdar, D, Basu, K, Razi, A, Ni, X, Guarne, A, Britton, R.A.
Deposit date:2019-07-06
Release date:2019-09-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural consequences of the interaction of RbgA with a 50S ribosomal subunit assembly intermediate.
Nucleic Acids Res., 47, 2019
6PVK
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BU of 6pvk by Molmil
Bacterial 45SRbgA ribosomal particle class A
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Ortega, J, Seffouh, A, Jain, N, Jahagirdar, D, Basu, K, Razi, A, Ni, X, Guarne, A, Britton, R.A.
Deposit date:2019-07-20
Release date:2019-09-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural consequences of the interaction of RbgA with a 50S ribosomal subunit assembly intermediate.
Nucleic Acids Res., 47, 2019
7MBW
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BU of 7mbw by Molmil
Crystal structure of TnsC(1-503)A225V
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transposon Tn7 transposition protein TnsC
Authors:Shen, Y, Guarne, A.
Deposit date:2021-04-01
Release date:2022-02-23
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for DNA targeting by the Tn7 transposon.
Nat.Struct.Mol.Biol., 29, 2022
7MCS
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BU of 7mcs by Molmil
Cryo-electron microscopy structure of TnsC(1-503)A225V bound to DNA
Descriptor: DNA (5'-D(P*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Shen, Y, Ortega, J, Guarne, A.
Deposit date:2021-04-02
Release date:2022-02-23
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Structural basis for DNA targeting by the Tn7 transposon.
Nat.Struct.Mol.Biol., 29, 2022
3SK7
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BU of 3sk7 by Molmil
Crystal Structure of V. cholerae SeqA
Descriptor: Protein SeqA
Authors:Chung, Y.S, Guarne, A.
Deposit date:2011-06-22
Release date:2012-12-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Investigating the aggregational property of SeqAvibrio in the absence of the oligomerization domain
To be Published
6BBK
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BU of 6bbk by Molmil
N-terminally truncated group I PilA from Pseudomonas aeruginosa strain 1244
Descriptor: Fimbrial protein
Authors:Shen, Y, Guarne, A, Nguyen, Y, Burrows, L.L.
Deposit date:2017-10-18
Release date:2018-11-21
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:N-terminally truncated group I PilA from Pseudomonas aeruginosa strain 1244
To Be Published
1FU1
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BU of 1fu1 by Molmil
CRYSTAL STRUCTURE OF HUMAN XRCC4
Descriptor: ACETIC ACID, DNA REPAIR PROTEIN XRCC4
Authors:Junop, M, Modesti, M, Guarne, A, Gellert, M, Yang, W.
Deposit date:2000-09-13
Release date:2000-12-11
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the Xrcc4 DNA repair protein and implications for end joining.
EMBO J., 19, 2000
3KSN
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BU of 3ksn by Molmil
Crystal structure of the lipoprotein localization factor, LolA
Descriptor: Outer-membrane lipoprotein carrier protein
Authors:Ahmadpour, F, Gloyd, M, Guarne, A, Stewart, G, Pathania, R, Brown, E.D.
Deposit date:2009-11-23
Release date:2010-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the lipoprotein localization factor, LolA
To be Published
5UZ4
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BU of 5uz4 by Molmil
The cryo-EM structure of YjeQ bound to the 30S subunit suggests a fidelity checkpoint function for this protein in ribosome assembly
Descriptor: 16S RIBOSOMAL RNA, 3'-O-(N-methylanthraniloyl)-beta:gamma-imidoguanosine-5'-triphosphate, 30S ribosomal protein S10, ...
Authors:Razi, A, Guarne, A, Ortega, J.
Deposit date:2017-02-24
Release date:2017-04-19
Last modified:2020-01-15
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:The cryo-EM structure of YjeQ bound to the 30S subunit suggests a fidelity checkpoint function for this protein in ribosome assembly.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5FBU
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BU of 5fbu by Molmil
Crystal structure of rifampin phosphotransferase RPH-Lm from Listeria monocytogenes in complex with rifampin-phosphate
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Phosphoenolpyruvate synthase, ...
Authors:Stogios, P.J, Wawrzak, Z, Skarina, T, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2015-12-14
Release date:2015-12-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Rifampin phosphotransferase is an unusual antibiotic resistance kinase.
Nat Commun, 7, 2016
8OZZ
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BU of 8ozz by Molmil
PH domain of AKT-like kinase in Trypanosoma cruzi
Descriptor: PH domain of Akt-like kinase in Trypanosoma cruzi
Authors:Stadler, K.A, Ortiz-Joya, L.J, Zangger, K, Gubensaek, N.
Deposit date:2023-05-09
Release date:2024-05-08
Method:SOLUTION NMR
Cite:Structural investigation of Trypanosoma cruzi Akt-like kinase as drug target against Chagas disease.
Sci Rep, 14, 2024
6I7P
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BU of 6i7p by Molmil
Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033)
Descriptor: NS5, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Ferrero, D.S, Ruiz-Arroyo, V.M, Soler, N, Uson, I, Verdaguer, N.
Deposit date:2018-11-16
Release date:2019-04-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.975 Å)
Cite:Supramolecular arrangement of the full-length Zika virus NS5.
Plos Pathog., 15, 2019
5M2Z
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BU of 5m2z by Molmil
Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033)
Descriptor: NS5, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Ferrero, D.S, Ruiz-Arroyo, V.M, Soler, N, Uson, I, Verdaguer, N.
Deposit date:2016-10-13
Release date:2018-06-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (4.8 Å)
Cite:Supramolecular arrangement of the full-length Zika virus NS5.
Plos Pathog., 15, 2019
5JMV
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BU of 5jmv by Molmil
Crystal structure of mjKae1-pfuPcc1 complex
Descriptor: ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein, ...
Authors:Wan, L, Sicheri, F.
Deposit date:2016-04-29
Release date:2016-07-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.3864696 Å)
Cite:Structural and functional characterization of KEOPS dimerization by Pcc1 and its role in t6A biosynthesis.
Nucleic Acids Res., 44, 2016
6PPK
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BU of 6ppk by Molmil
RbgA+45SRbgA complex
Descriptor: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
Authors:Ortega, J.
Deposit date:2019-07-07
Release date:2019-09-18
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural consequences of the interaction of RbgA with a 50S ribosomal subunit assembly intermediate.
Nucleic Acids Res., 47, 2019
5M2X
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BU of 5m2x by Molmil
Crystal structure of the full-length Zika virus NS5 protein (Human isolate Z1106033)
Descriptor: NS5, PHOSPHATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Ferrero, D.S, Ruiz-Arroyo, V.M, Soler, N, Uson, I, Verdaguer, N.
Deposit date:2016-10-13
Release date:2018-06-06
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (4.991 Å)
Cite:Supramolecular arrangement of the full-length Zika virus NS5.
Plos Pathog., 15, 2019
4O1P
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BU of 4o1p by Molmil
Crystal Structure of RNase L in complex with 2-5A and AMP-PNP
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonuclease L, ...
Authors:Huang, H, Zeqiraj, E, Ceccarelli, D.F, Sicheri, F.
Deposit date:2013-12-16
Release date:2014-02-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity.
Mol.Cell, 53, 2014

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數據於2024-11-06公開中

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