6F6Z
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![BU of 6f6z by Molmil](/molmil-images/mine/6f6z) | Mouse Thymidylate Synthase Cocrystallized with N(4)OHdCMP and Soaked in Methylenetetrahydrofolate | Descriptor: | (2~{S})-2-[[4-[[(6~{R})-2-azanyl-4-oxidanylidene-5,6,7,8-tetrahydro-1~{H}-pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid, 2'-deoxy-N-hydroxycytidine 5'-(dihydrogen phosphate), Thymidylate synthase | Authors: | Wilk, P, Jarmula, A, Maj, P, Rode, W. | Deposit date: | 2017-12-06 | Release date: | 2019-01-30 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.127 Å) | Cite: | Molecular Mechanism of Thymidylate Synthase Inhibition by N4-Hydroxy-dCMP in View of Spectrophotometric and Crystallographic Studies Int J Mol Sci, 22, 2021
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7OP9
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![BU of 7op9 by Molmil](/molmil-images/mine/7op9) | Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 2,6-dichloropurine | Descriptor: | 2,6-bis(chloranyl)-7H-purine, IMIDAZOLE, MAGNESIUM ION, ... | Authors: | Narczyk, M, Stefanic, Z. | Deposit date: | 2021-05-31 | Release date: | 2022-05-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium. J Enzyme Inhib Med Chem, 37, 2022
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7OOZ
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![BU of 7ooz by Molmil](/molmil-images/mine/7ooz) | Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 6-benzyloxo-2-chloropurine | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-benzyloxo-2-chloropurine, GLYCEROL, ... | Authors: | Narczyk, M, Stefanic, Z. | Deposit date: | 2021-05-28 | Release date: | 2022-05-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium. J Enzyme Inhib Med Chem, 37, 2022
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7OPA
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![BU of 7opa by Molmil](/molmil-images/mine/7opa) | Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 6-benzylthiopurine | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-benzylthio-2-chloropurine, GLYCEROL, ... | Authors: | Narczyk, M, Stefanic, Z. | Deposit date: | 2021-05-31 | Release date: | 2022-05-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium. J Enzyme Inhib Med Chem, 37, 2022
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7OOY
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![BU of 7ooy by Molmil](/molmil-images/mine/7ooy) | Purine nucleoside phosphorylase(DeoD-type) from H. pylori with 6-benzylthio-2-chloropurine | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-benzylthio-2-chloropurine, GLYCEROL, ... | Authors: | Narczyk, M, Stefanic, Z. | Deposit date: | 2021-05-28 | Release date: | 2022-05-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium. J Enzyme Inhib Med Chem, 37, 2022
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5MX6
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![BU of 5mx6 by Molmil](/molmil-images/mine/5mx6) | |
5MX4
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![BU of 5mx4 by Molmil](/molmil-images/mine/5mx4) | |
5MX8
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![BU of 5mx8 by Molmil](/molmil-images/mine/5mx8) | |
6F52
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![BU of 6f52 by Molmil](/molmil-images/mine/6f52) | |
6F4W
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![BU of 6f4w by Molmil](/molmil-images/mine/6f4w) | Crystal structure of H. pylori purine nucleoside phosphorylase in complex with formycin A | Descriptor: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, Purine nucleoside phosphorylase DeoD-type | Authors: | Stefanic, Z. | Deposit date: | 2017-11-30 | Release date: | 2018-02-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.293 Å) | Cite: | Helicobacter pylori purine nucleoside phosphorylase shows new distribution patterns of open and closed active site conformations and unusual biochemical features. FEBS J., 285, 2018
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6F5I
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![BU of 6f5i by Molmil](/molmil-images/mine/6f5i) | Crystal structure of H. pylori purine nucleoside phosphorylase | Descriptor: | METHANOL, Purine nucleoside phosphorylase DeoD-type | Authors: | Stefanic, Z. | Deposit date: | 2017-12-01 | Release date: | 2018-02-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.298 Å) | Cite: | Helicobacter pylori purine nucleoside phosphorylase shows new distribution patterns of open and closed active site conformations and unusual biochemical features. FEBS J., 285, 2018
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6F5A
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![BU of 6f5a by Molmil](/molmil-images/mine/6f5a) | Crystal structure of H. pylori purine nucleoside phosphorylase | Descriptor: | Purine nucleoside phosphorylase DeoD-type | Authors: | Stefanic, Z. | Deposit date: | 2017-12-01 | Release date: | 2018-02-14 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Helicobacter pylori purine nucleoside phosphorylase shows new distribution patterns of open and closed active site conformations and unusual biochemical features. FEBS J., 285, 2018
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6F4X
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![BU of 6f4x by Molmil](/molmil-images/mine/6f4x) | |