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7B5J
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BU of 7b5j by Molmil
Anti-CRISPR associated (Aca) protein, Aca2
Descriptor: Anti-CRISPR associated (Aca) protein, Aca2, GLYCEROL
Authors:Usher, B, Birkholz, N, Fineran, P.C, Blower, T.R.
Deposit date:2020-12-03
Release date:2021-06-23
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:Crystal structure of the anti-CRISPR repressor Aca2.
J.Struct.Biol., 213, 2021
7ZBG
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BU of 7zbg by Molmil
Human Topoisomerase II Beta ATPase ADP
Descriptor: 4-[(2S,3R)-3-[3,5-bis(oxidanylidene)piperazin-1-ium-1-yl]butan-2-yl]piperazin-4-ium-2,6-dione, ADENOSINE-5'-DIPHOSPHATE, DNA topoisomerase 2-beta, ...
Authors:Ling, E.M, Basle, A, Cowell, I.G, Blower, T.R, Austin, C.A.
Deposit date:2022-03-23
Release date:2022-05-25
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:A comprehensive structural analysis of the ATPase domain of human DNA topoisomerase II beta bound to AMPPNP, ADP, and the bisdioxopiperazine, ICRF193.
Structure, 30, 2022
8AN4
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BU of 8an4 by Molmil
MenT1 toxin (rv0078a) from Mycobacterium tuberculosis H37Rv
Descriptor: Bacterial toxin
Authors:Xu, X, Usher, B, Gutierrez, C, Barriot, R, Arrowsmith, T.J, Han, X, Redder, P, Neyrolles, O, Blower, T.R, Genevaux, P.
Deposit date:2022-08-04
Release date:2023-08-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:MenT nucleotidyltransferase toxins extend tRNA acceptor stems and can be inhibited by asymmetrical antitoxin binding.
Nat Commun, 14, 2023
8AN5
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BU of 8an5 by Molmil
MenAT1 toxin-antitoxin complex (rv0078a-rv0078b) from Mycobacterium tuberculosis H37Rv
Descriptor: Bacterial toxin, Conserved protein
Authors:Xu, X, Usher, B, Gutierrez, C, Barriot, R, Arrowsmith, T.J, Han, X, Redder, P, Neyrolles, O, Blower, T.R, Genevaux, P.
Deposit date:2022-08-04
Release date:2023-08-02
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:MenT nucleotidyltransferase toxins extend tRNA acceptor stems and can be inhibited by asymmetrical antitoxin binding.
Nat Commun, 14, 2023
8C24
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BU of 8c24 by Molmil
ParDE1 toxin-antitoxin complex from Mycobacterium tuberculosis (rv1960c-rv1959c)
Descriptor: Antitoxin ParD1, Toxin ParE1
Authors:Beck, I.N, Blower, T.R.
Deposit date:2022-12-21
Release date:2023-12-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Toxin release by conditional remodelling of ParDE1 from Mycobacterium tuberculosis leads to gyrase inhibition.
Nucleic Acids Res., 52, 2024
8C26
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BU of 8c26 by Molmil
ParDE2 toxin-antitoxin complex from Mycobacterium tuberculosis (rv2142A-rv2142c)
Descriptor: Antitoxin ParD2, CHLORIDE ION, Toxin ParE2
Authors:Beck, I.N, Blower, T.R.
Deposit date:2022-12-21
Release date:2023-12-20
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Toxin release by conditional remodelling of ParDE1 from Mycobacterium tuberculosis leads to gyrase inhibition.
Nucleic Acids Res., 52, 2024
6Y56
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BU of 6y56 by Molmil
MenT4, nucleotidyltransferase toxin Rv2826c from Mycobacterium tuberculosis H37Rv
Descriptor: Uncharacterized protein
Authors:Usher, B, Blower, T.R.
Deposit date:2020-02-24
Release date:2020-09-16
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:A nucleotidyltransferase toxin inhibits growth of Mycobacterium tuberculosis through inactivation of tRNA acceptor stems.
Sci Adv, 6, 2020
8W35
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BU of 8w35 by Molmil
Aca2 from Pectobacterium phage ZF40 bound to RNA
Descriptor: Anti-CRISPR associated (Aca) protein, Aca2, IR2 and IR-RBS RNA
Authors:Wilkinson, M.E, Birkholz, N, Kimanius, D, Fineran, P.C.
Deposit date:2024-02-21
Release date:2024-07-24
Last modified:2024-08-14
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Phage anti-CRISPR control by an RNA- and DNA-binding helix-turn-helix protein.
Nature, 631, 2024
4RMO
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BU of 4rmo by Molmil
Crystal Structure of the CptIN Type III Toxin-Antitoxin System from Eubacterium rectale
Descriptor: CALCIUM ION, CptN Toxin, RNA (45-MER)
Authors:Rao, F, Voss, J.E, Short, F.L, Luisi, B.F.
Deposit date:2014-10-21
Release date:2015-09-30
Last modified:2015-11-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Co-evolution of quaternary organization and novel RNA tertiary interactions revealed in the crystal structure of a bacterial protein-RNA toxin-antitoxin system.
Nucleic Acids Res., 43, 2015
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數據於2024-10-09公開中

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