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2QN2
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BU of 2qn2 by Molmil
Glycogen Phosphorylase b in complex with Maslinic Acid
Descriptor: Glycogen phosphorylase, muscle form, maslinic acid
Authors:Zographos, S.E, Leonidas, D.D, Alexacou, K.-M, Hayes, J, Oikonomakos, N.G.
Deposit date:2007-07-17
Release date:2008-06-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.698 Å)
Cite:Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies
J.Med.Chem., 51, 2008
6IQI
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BU of 6iqi by Molmil
crystal structure of Arabidopsis thaliana Profilin 2
Descriptor: Profilin-2
Authors:Qiao, Z, Gao, Y.
Deposit date:2018-11-08
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and computational examination of theArabidopsisprofilin-Poly-P complex reveals mechanistic details in profilin-regulated actin assembly.
J.Biol.Chem., 294, 2019
7DQ7
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BU of 7dq7 by Molmil
Cryo-EM structure of Coxsackievirus B1 mature virion in complex with nAb 5F5
Descriptor: 5F5 VH, 5F5 VL, Capsid protein VP4, ...
Authors:Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q.
Deposit date:2020-12-22
Release date:2021-05-05
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7DPF
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BU of 7dpf by Molmil
Cryo-EM structure of Coxsackievirus B1 mature virion
Descriptor: Capsid protein VP4, PALMITIC ACID, VP2, ...
Authors:Zheng, Q, Li, S.
Deposit date:2020-12-18
Release date:2021-05-05
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7DQ4
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BU of 7dq4 by Molmil
Cryo-EM structure of CAR triggered Coxsackievirus B1 A-particle
Descriptor: VP2, VP3, Virion protein 1
Authors:Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q.
Deposit date:2020-12-22
Release date:2021-05-05
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7DPZ
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BU of 7dpz by Molmil
Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR
Descriptor: Capsid protein VP4, Coxsackievirus and adenovirus receptor, VP2, ...
Authors:Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q.
Deposit date:2020-12-22
Release date:2021-05-05
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7DPG
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BU of 7dpg by Molmil
Cryo-EM structure of Coxsackievirus B1 empty particle
Descriptor: VP2, VP3, Virion protein 1
Authors:Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q, Xia, N.
Deposit date:2020-12-18
Release date:2021-05-05
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7DQ1
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BU of 7dq1 by Molmil
Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR at physiological temperature
Descriptor: Capsid protein VP4, Coxsackievirus and adenovirus receptor, VP2, ...
Authors:Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q.
Deposit date:2020-12-22
Release date:2021-05-05
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
6IQK
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BU of 6iqk by Molmil
crystal structure of Arabidopsis thaliana Profilin 3
Descriptor: AtPRF3, Profilin-5
Authors:Qiao, Z, Gao, Y.
Deposit date:2018-11-08
Release date:2019-11-06
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural and computational examination of theArabidopsisprofilin-Poly-P complex reveals mechanistic details in profilin-regulated actin assembly.
J.Biol.Chem., 294, 2019
6IQF
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BU of 6iqf by Molmil
crystal structure of Arabidopsis thaliana Profilin 3
Descriptor: PRF3
Authors:Qiao, Z, Gao, Y.
Deposit date:2018-11-07
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.457 Å)
Cite:Structural and computational examination of theArabidopsisprofilin-Poly-P complex reveals mechanistic details in profilin-regulated actin assembly.
J.Biol.Chem., 294, 2019
6IQJ
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BU of 6iqj by Molmil
crystal structure of Arabidopsis thaliana Profilin 2 complex with formin1
Descriptor: Formin-like protein 1, Profilin-2
Authors:Qiao, Z, Gao, Y.
Deposit date:2018-11-08
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.922 Å)
Cite:Structural and computational examination of theArabidopsisprofilin-Poly-P complex reveals mechanistic details in profilin-regulated actin assembly.
J.Biol.Chem., 294, 2019
6J67
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BU of 6j67 by Molmil
Crystal structure of the compound 34 in a complex with TRF2
Descriptor: 3FB-PHE-B8R-LEU-5XU-PRO, Telomeric repeat-binding factor 2
Authors:Chen, Y, Yang, Y, Lei, M.
Deposit date:2019-01-14
Release date:2019-02-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Cyclic Peptidic Mimetics of Apollo Peptides Targeting Telomeric Repeat Binding Factor 2 (TRF2) and Apollo Interaction.
ACS Med Chem Lett, 9, 2018
7EAM
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BU of 7eam by Molmil
immune complex of SARS-CoV-2 RBD and cross-neutralizing antibody 7D6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ...
Authors:Li, T.T, Gu, Y, Li, S.W.
Deposit date:2021-03-07
Release date:2021-03-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants.
Nat Commun, 12, 2021
7EAN
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BU of 7ean by Molmil
immune complex of SARS-CoV-2 RBD and cross-neutralizing antibody 6D6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of SARS-CoV-2 cross-neutralizing mAb 6D6, Light chain of SARS-CoV-2 cross-neutralizing mAb 6D6, ...
Authors:Li, T.T, Gu, Y, Li, S.W.
Deposit date:2021-03-07
Release date:2021-03-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Cross-neutralizing antibodies bind a SARS-CoV-2 cryptic site and resist circulating variants.
Nat Commun, 12, 2021
6KKN
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BU of 6kkn by Molmil
Crystal structure of RuBisCO accumulation factor Raf1 from Anabaena sp. PCC 7120
Descriptor: All5250 protein
Authors:Xia, L.Y, Jiang, Y.L, Kong, W.W, Chen, Y, Zhou, C.Z.
Deposit date:2019-07-26
Release date:2020-05-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Molecular basis for the assembly of RuBisCO assisted by the chaperone Raf1.
Nat.Plants, 6, 2020
6KKM
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BU of 6kkm by Molmil
Crystal structure of RbcL-Raf1 complex from Anabaena sp. PCC 7120
Descriptor: All5250 protein, Ribulose bisphosphate carboxylase large chain
Authors:Xia, L.Y, Jiang, Y.L, Kong, W.W, Chen, Y, Zhou, C.Z.
Deposit date:2019-07-26
Release date:2020-05-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular basis for the assembly of RuBisCO assisted by the chaperone Raf1.
Nat.Plants, 6, 2020
7WWM
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BU of 7wwm by Molmil
S protein of Delta variant in complex with ZWC6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Guo, Y.Y, Zhang, Y.Y, Zhou, Q.
Deposit date:2022-02-13
Release date:2022-06-01
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Broadly neutralizing antibodies against Omicron-included SARS-CoV-2 variants induced by vaccination.
Signal Transduct Target Ther, 7, 2022
7WWL
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BU of 7wwl by Molmil
S protein of Delta variant in complex with ZWD12
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Guo, Y.Y, Zhang, Y.Y, Zhou, Q.
Deposit date:2022-02-13
Release date:2022-06-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Broadly neutralizing antibodies against Omicron-included SARS-CoV-2 variants induced by vaccination.
Signal Transduct Target Ther, 7, 2022
8IA3
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BU of 8ia3 by Molmil
Crystal structure of human USF2 bHLHLZ domain in complex with DNA
Descriptor: DNA (5'-D(*GP*CP*GP*CP*GP*TP*CP*AP*CP*GP*TP*GP*CP*CP*CP*GP*TP*C)-3'), DNA (5'-D(P*GP*AP*CP*GP*GP*GP*CP*AP*CP*GP*TP*GP*AP*CP*GP*CP*GP*C)-3'), Upstream stimulatory factor 2
Authors:Huang, C, Fang, P, Wang, J.
Deposit date:2023-02-07
Release date:2023-09-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Tetramerization of upstream stimulating factor USF2 requires the elongated bent leucine zipper of the bHLH-LZ domain.
J.Biol.Chem., 299, 2023
7VXG
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BU of 7vxg by Molmil
Non-receptor Protein Tyrosine Phosphatase SHP2 in Complex with Allosteric Inhibitor TK-453
Descriptor: 6-[4-(aminomethyl)-4-methyl-piperidin-1-yl]-3-[2,3-bis(chloranyl)phenyl]sulfanyl-pyrazin-2-amine, Tyrosine-protein phosphatase non-receptor type 11
Authors:Li, T.H, Guo, H.T, Ji, X.Y.
Deposit date:2021-11-12
Release date:2022-03-23
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:SHP2 allosteric inhibitor TK-453 alleviates psoriasis-like skin inflammation in mice via inhibition of IL-23/Th17 axis.
Iscience, 25, 2022
7E5W
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BU of 7e5w by Molmil
The structure of CcpA from Staphylococcus aureus
Descriptor: Catabolite control protein A, SULFATE ION
Authors:Yu, G, Wei, X.
Deposit date:2021-02-20
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Regulation of DNA-binding activity of the Staphylococcus aureus catabolite control protein A by copper (II)-mediated oxidation.
J.Biol.Chem., 298, 2022
7DGB
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BU of 7dgb by Molmil
The co-crystal structure of SARS-CoV-2 main protease with (S)-2-cinnamamido-4-methyl-N-((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)pentanamide
Descriptor: (2~{S})-4-methyl-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]pentanamide, 3C-like proteinase
Authors:Shang, L.Q, Wang, H.
Deposit date:2020-11-11
Release date:2021-11-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.678 Å)
Cite:The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate.
Eur.J.Med.Chem., 238, 2022
7DGH
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BU of 7dgh by Molmil
The co-crystal structure of SARS-CoV-2 main protease with peptidomimetic inhibitor N-((S)-3-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopiperidin-3-yl)propan-2-yl)amino)pentan-2-yl)amino)-1-oxobutan-2-yl)-2-naphthamide
Descriptor: 3C-like proteinase, ~{N}-[(2~{S})-3-methyl-1-[[(2~{S})-4-methyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]amino]pentan-2-yl]amino]-1-oxidanylidene-butan-2-yl]naphthalene-2-carboxamide
Authors:Shang, L.Q, Wang, H.
Deposit date:2020-11-11
Release date:2021-11-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.968 Å)
Cite:The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate.
Eur.J.Med.Chem., 238, 2022
7DGF
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BU of 7dgf by Molmil
The co-crystal structure of SARS-CoV-2 main protease with peptidomimetic inhibitor (S)-2-cinnamamido-N-((S)-1-oxo-3-((S)-2-oxopiperidin-3-yl)propan-2-yl)hexanamide
Descriptor: (2~{S})-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]hexanamide, 3C-like proteinase
Authors:Shang, L.Q, Wang, H.
Deposit date:2020-11-11
Release date:2021-11-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.639 Å)
Cite:The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate.
Eur.J.Med.Chem., 238, 2022
7DHJ
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BU of 7dhj by Molmil
The co-crystal structure of SARS-CoV-2 main protease with the peptidomimetic inhibitor (S)-2-cinnamamido-N-((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)pent-4-ynamide
Descriptor: (2~{S})-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]pent-4-ynamide, 3C-like proteinase
Authors:Shang, L.Q, Wang, H, Deng, W.L, Xing, S, Wang, Y.X.
Deposit date:2020-11-15
Release date:2021-11-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.962 Å)
Cite:The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate.
Eur.J.Med.Chem., 238, 2022

223790

數據於2024-08-14公開中

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