Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
8K72
DownloadVisualize
BU of 8k72 by Molmil
Factor-inhibiting hypoxia-inducible factor in complex with Zn(II) and 2-(3-hydroxy-2-((3-(phenylsulfonamido)propanoyl)imino)-2,3-dihydrothiazol-4-yl)acetic acid
Descriptor: 2-[(2~{Z})-3-oxidanyl-2-[3-(phenylsulfonylamino)propanoylimino]-1,3-thiazol-4-yl]ethanoic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ...
Authors:Nakashima, Y, Corner, T.P, Teo, R.Z.R, Brewitz, L, Schofield, C.J.
Deposit date:2023-07-26
Release date:2023-12-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure-guided optimisation of N -hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-alpha.
Chem Sci, 14, 2023
8K73
DownloadVisualize
BU of 8k73 by Molmil
Factor-inhibiting hypoxia-inducible factor in complex with Zn(II) and 2-(3-hydroxy-2-((1-(phenylsulfonyl)pyrrolidine-3-carbonyl)imino)-2,3-dihydrothiazol-4-yl)acetic acid
Descriptor: 2-[(2~{Z})-3-oxidanyl-2-[(3~{R})-1-(phenylsulfonyl)pyrrolidin-3-yl]carbonylimino-1,3-thiazol-4-yl]ethanoic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ...
Authors:Nakashima, Y, Corner, T.P, Teo, R.Z.R, Brewitz, L, Schofield, C.J.
Deposit date:2023-07-26
Release date:2023-12-13
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Structure-guided optimisation of N -hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-alpha.
Chem Sci, 14, 2023
8PA8
DownloadVisualize
BU of 8pa8 by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2551
Descriptor: 7-[(1~{S})-1-[4-(3-azanylpropyl)-1,2,3-triazol-1-yl]ethyl]-3-[3-chloranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-07
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2551
To Be Published
8P92
DownloadVisualize
BU of 8p92 by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2117
Descriptor: 3-[(1~{S})-1-phenylethoxy]-7-propan-2-yl-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-05
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2117
To Be Published
8P9P
DownloadVisualize
BU of 8p9p by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2408
Descriptor: 3-(2-ethoxy-5-fluoranyl-pyridin-3-yl)-7-propan-2-yl-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-06
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.14 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2408
To Be Published
8PAO
DownloadVisualize
BU of 8pao by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2654
Descriptor: 7-[(1~{S})-1-[4-[(2-azanylethylsulfonylamino)methyl]-1,2,3-triazol-1-yl]ethyl]-3-[3-fluoranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-08
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2654
To Be Published
8PA7
DownloadVisualize
BU of 8pa7 by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2546
Descriptor: 3-[4-[[[(2~{S})-2-azanyl-3-oxidanyl-propanoyl]amino]methyl]-3-fluoranyl-phenyl]-7-propan-2-yl-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, DIMETHYL SULFOXIDE, ...
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-07
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2546
To Be Published
8PA4
DownloadVisualize
BU of 8pa4 by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2526
Descriptor: 3-[4-(carbamimidamidomethyl)-3-fluoranyl-phenyl]-7-propan-2-yl-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-07
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2526
To Be Published
8P7O
DownloadVisualize
BU of 8p7o by Molmil
Isopenicillin N synthase in complex with Fe and Aad-Cys-[(S)-1-amino-2-methylpropane-1-sulfonic acid]
Descriptor: (2~{S})-2-azanyl-6-[[(2~{R})-1-[[(1~{S})-2-methyl-1-sulfo-propyl]amino]-1-oxidanylidene-3-sulfanyl-propan-2-yl]amino]-6-oxidanylidene-hexanoic acid, FE (III) ION, Isopenicillin N synthase, ...
Authors:Rabe, P, Schofield, C.J.
Deposit date:2023-05-30
Release date:2024-06-12
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Isopenicillin N synthase in complex with Fe and Aad-Cys-[(S)-1-amino-2-methylpropane-1-sulfonic acid]
To Be Published
8P7P
DownloadVisualize
BU of 8p7p by Molmil
Isopenicillin N synthase in complex with Fe and Aad-Val-[(R)-1-amino-2-methylpropane-1-sulfonic acid]
Descriptor: (2~{S})-2-azanyl-6-[[(2~{R})-1-[[(1~{R})-2-methyl-1-sulfo-propyl]amino]-1-oxidanylidene-3-sulfanyl-propan-2-yl]amino]-6-oxidanylidene-hexanoic acid, FE (III) ION, Isopenicillin N synthase, ...
Authors:Rabe, P, Schofield, C.J.
Deposit date:2023-05-30
Release date:2024-06-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Isopenicillin N synthase in complex with Fe and Aad-Val-[(R)-1-amino-2-methylpropane-1-sulfonic acid]
To Be Published
8PAL
DownloadVisualize
BU of 8pal by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2651
Descriptor: 7-[(1~{S})-1-[[4-(aminomethyl)phenyl]methoxy]ethyl]-3-[3-chloranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-08
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2651
To Be Published
8P95
DownloadVisualize
BU of 8p95 by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2407
Descriptor: 3-(2-ethoxypyridin-3-yl)-7-propan-2-yl-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-05
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.09 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2407
To Be Published
8P9S
DownloadVisualize
BU of 8p9s by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2482
Descriptor: 7-[(1~{S})-1-[4-(aminomethyl)phenyl]carbonyloxyethyl]-3-[3-chloranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, DIMETHYL SULFOXIDE, ...
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-06
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2482
To Be Published
8PAD
DownloadVisualize
BU of 8pad by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2555
Descriptor: 7-[(1~{S})-1-[[4-(aminomethyl)phenyl]carbonylamino]ethyl]-3-[6-(morpholin-4-ylmethyl)pyridin-3-yl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-07
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2555
To Be Published
8PB2
DownloadVisualize
BU of 8pb2 by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2697
Descriptor: 7-[(1~{S})-1-[4-(carbamimidamidomethyl)-1,2,3-triazol-1-yl]ethyl]-3-[3-fluoranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-08
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2697
To Be Published
8PAC
DownloadVisualize
BU of 8pac by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2553
Descriptor: 7-[(1~{S})-1-[4-(aminomethyl)phenyl]carbonyloxyethyl]-3-[6-(morpholin-4-ylmethyl)pyridin-3-yl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-07
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2553
To Be Published
8PB0
DownloadVisualize
BU of 8pb0 by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2696
Descriptor: 7-[(1~{S})-1-[4-[[[(2~{S})-2-azanyl-3-oxidanyl-propanoyl]amino]methyl]-1,2,3-triazol-1-yl]ethyl]-3-[3-fluoranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-08
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2696
To Be Published
8P47
DownloadVisualize
BU of 8p47 by Molmil
IPNS variant N252A in complex with Fe and ACV under anaerobic conditions
Descriptor: FE (III) ION, Isopenicillin N synthase, L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE, ...
Authors:Rabe, P, Schofield, C.J.
Deposit date:2023-05-19
Release date:2024-06-05
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:IPNS variant N252A in complex with Fe and ACV under anaerobic conditions
To Be Published
8P46
DownloadVisualize
BU of 8p46 by Molmil
IPNS variant N252D in complex with Fe and IPN after O2 exposure
Descriptor: FE (III) ION, ISOPENICILLIN N, Isopenicillin N synthase, ...
Authors:Rabe, P, Schofield, C.J.
Deposit date:2023-05-19
Release date:2024-06-05
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:IPNS variant N252D in complex with Fe and IPN after O2 exposure
To Be Published
8P48
DownloadVisualize
BU of 8p48 by Molmil
IPNS variant N252D in complex with Fe and ACV under anaerobic conditions
Descriptor: FE (III) ION, Isopenicillin N synthase, L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE, ...
Authors:Rabe, P, Schofield, C.J.
Deposit date:2023-05-19
Release date:2024-06-05
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:IPNS variant N252D in complex with Fe and ACV under anaerobic conditions
To Be Published
8P8Z
DownloadVisualize
BU of 8p8z by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 1963
Descriptor: 3-[3-cyano-4-(methylsulfonylmethyl)phenyl]-7-propan-2-yl-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-04
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 1963
To Be Published
8PA3
DownloadVisualize
BU of 8pa3 by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2500
Descriptor: 7-[(1~{S})-1-[4-(2-azanylethyl)phenoxy]ethyl]-3-[3-chloranyl-4-(methylsulfonylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-07
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2500
To Be Published
8P93
DownloadVisualize
BU of 8p93 by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2163
Descriptor: 3-[3-fluoranyl-4-[(piperidin-4-ylsulfonylamino)methyl]phenyl]-7-propan-2-yl-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-05
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.13 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2163
To Be Published
8P9Q
DownloadVisualize
BU of 8p9q by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2455
Descriptor: 7-[(1~{S})-1-acetyloxyethyl]-3-[3-fluoranyl-4-(sulfamoylmethyl)phenyl]-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, DIMETHYL SULFOXIDE, ...
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-06
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2455
To Be Published
8PA5
DownloadVisualize
BU of 8pa5 by Molmil
Crystal structure of the metallo-beta-lactamase VIM1 with 2540
Descriptor: 3-(3-ethoxy-5-methyl-pyridin-4-yl)-7-propan-2-yl-1~{H}-indole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION
Authors:Calvopina, K, Brem, J, Farley, A.J.M, Allen, M.D, Schofield, C.J.
Deposit date:2023-06-07
Release date:2024-06-26
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Crystal structure of the metallo-beta-lactamase VIM1 with 2540
To Be Published

225158

數據於2024-09-18公開中

PDB statisticsPDBj update infoContact PDBjnumon