8CLL
 
 | | Structural insights into human TFIIIC promoter recognition | | Descriptor: | General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 2, General transcription factor 3C polypeptide 4, ... | | Authors: | Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W. | | Deposit date: | 2023-02-16 | | Release date: | 2023-06-21 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Structural insights into human TFIIIC promoter recognition.
Sci Adv, 9, 2023
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8CLI
 | | TFIIIC TauB-DNA monomer | | Descriptor: | DNA (35-MER), General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 2, ... | | Authors: | Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W. | | Deposit date: | 2023-02-16 | | Release date: | 2023-06-21 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insights into human TFIIIC promoter recognition.
Sci Adv, 9, 2023
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8CLK
 | | TFIIIC TauA complex | | Descriptor: | General transcription factor 3C polypeptide 1, General transcription factor 3C polypeptide 3, General transcription factor 3C polypeptide 5, ... | | Authors: | Seifert-Davila, W, Girbig, M, Hauptmann, L, Hoffmann, T, Eustermann, S, Mueller, C.W. | | Deposit date: | 2023-02-16 | | Release date: | 2023-06-21 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural insights into human TFIIIC promoter recognition.
Sci Adv, 9, 2023
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4CN6
 | | GlgE isoform 1 from Streptomyces coelicolor E423A mutant with maltose bound | | Descriptor: | ALPHA-1,4-GLUCAN:MALTOSE-1-PHOSPHATE MALTOSYLTRANSFERASE 1, alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose | | Authors: | Syson, K, Stevenson, C.E.M, Rashid, A.M, Saalbach, G, Tang, M, Tuukanen, A, Svergun, D.I, Withers, S.G, Lawson, D.M, Bornemann, S. | | Deposit date: | 2014-01-21 | | Release date: | 2014-05-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | Structural Insight Into How Streptomyces Coelicolor Maltosyl Transferase Glge Binds Alpha-Maltose 1-Phosphate and Forms a Maltosyl-Enzyme Intermediate.
Biochemistry, 53, 2014
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6G9E
 | | Crystal structure of immunomodulatory active chitinase from Trichuris suis - TsES1 - 6 molecules in ASU | | Descriptor: | 1,2-ETHANEDIOL, Immunomodulatory active chitinase | | Authors: | Malecki, P.H, Balster, K, Hartmann, S, Weiss, M.S, Heinemann, U. | | Deposit date: | 2018-04-10 | | Release date: | 2019-04-24 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | A Helminth-Derived Chitinase Structurally Similar to Mammalian Chitinase Displays Immunomodulatory Properties in Inflammatory Lung Disease.
J Immunol Res, 2021, 2021
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6G9C
 | | Crystal structure of immunomodulatory active chitinase from Trichuris suis, TsES1 | | Descriptor: | 1,2-ETHANEDIOL, Immunomodulatory active chitinase | | Authors: | Malecki, P.H, Balster, K, Hartmann, S, Weiss, M.S, Heinemann, U. | | Deposit date: | 2018-04-10 | | Release date: | 2019-04-24 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | A Helminth-Derived Chitinase Structurally Similar to Mammalian Chitinase Displays Immunomodulatory Properties in Inflammatory Lung Disease.
J Immunol Res, 2021, 2021
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4CN1
 | | GlgE isoform 1 from Streptomyces coelicolor D394A mutant with maltose- 1-phosphate bound | | Descriptor: | ALPHA-1,4-GLUCAN: MALTOSE-1-PHOSPHATE MALTOSYLTRANSFERASE 1, alpha-D-glucopyranose-(1-4)-1-O-phosphono-alpha-D-glucopyranose | | Authors: | Syson, K, Stevenson, C.E.M, Rashid, A.M, Saalbach, G, Tang, M, Tuukanen, A, Svergun, D.I, Withers, S.G, Lawson, D.M, Bornemann, S. | | Deposit date: | 2014-01-21 | | Release date: | 2014-05-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural Insight Into How Streptomyces Coelicolor Maltosyl Transferase Glge Binds Alpha-Maltose 1-Phosphate and Forms a Maltosyl-Enzyme Intermediate.
Biochemistry, 53, 2014
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4CQ6
 | | The crystal structure of the allene oxide cyclase 2 from Arabidopsis thaliana with bound inhibitor - vernolic acid | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (9Z)-11-[(2R,3S)-3-pentyloxiran-2-yl]undec-9-enoic acid, ALLENE OXIDE CYCLASE 2, ... | | Authors: | Terlecka, B.A, Pollmann, S, Hofmann, E. | | Deposit date: | 2014-02-11 | | Release date: | 2015-03-04 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Ligand-Bound Structures of the Aoc2 from A. Thaliana and the Implications for the Catalytic Mechanism
To be Published
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4CN4
 | | GlgE isoform 1 from Streptomyces coelicolor E423A mutant with 2-deoxy- 2-fluoro-beta-maltosyl modification | | Descriptor: | ALPHA-1,4-GLUCAN:MALTOSE-1-PHOSPHATE MALTOSYLTRANSFERASE 1, alpha-D-glucopyranose-(1-4)-2-deoxy-2-fluoro-beta-D-glucopyranose | | Authors: | Syson, K, Stevenson, C.E.M, Rashid, A.M, Saalbach, G, Tang, M, Tuukanen, A, Svergun, D.I, Withers, S.G, Lawson, D.M, Bornemann, S. | | Deposit date: | 2014-01-21 | | Release date: | 2014-05-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Insight Into How Streptomyces Coelicolor Maltosyl Transferase Glge Binds Alpha-Maltose 1-Phosphate and Forms a Maltosyl-Enzyme Intermediate.
Biochemistry, 53, 2014
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4CQ7
 | | The crystal structure of the allene oxide cyclase 2 from Arabidopsis thaliana with bound product - OPDA | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, 9S,13R-12-OXOPHYTODIENOIC ACID, ALLENE OXIDE CYCLASE 2, ... | | Authors: | Terlecka, B.A, Pollmann, S, Hofmann, E. | | Deposit date: | 2014-02-11 | | Release date: | 2015-03-04 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Ligand-Bound Structures of the Aoc2 from A. Thaliana and the Implications for the Catalytic Mechanism
To be Published
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5DZW
 | | Protocadherin alpha 4 extracellular cadherin domains 1-4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Protocadherin alpha-4, ... | | Authors: | Goodman, K.M, Bahna, F, Mannepalli, S, Honig, B, Shapiro, L. | | Deposit date: | 2015-09-26 | | Release date: | 2016-05-04 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.43 Å) | | Cite: | Structural Basis of Diverse Homophilic Recognition by Clustered alpha- and beta-Protocadherins.
Neuron, 90, 2016
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8C3U
 | | Crystal Structure of human IL-1beta in complex with a low molecular weight antagonist | | Descriptor: | (S)-4'-hydroxy-3'-(6-methyl-2-oxo-3-(1H-pyrazol-4-yl)indolin-3-yl)-[1,1'-biphenyl]-2,4-dicarboxylic acid, Interleukin-1 beta | | Authors: | Rondeau, J.-M, Lehmann, S, Koch, E. | | Deposit date: | 2022-12-28 | | Release date: | 2023-09-13 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (1.945 Å) | | Cite: | Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1 beta.
Nat Commun, 14, 2023
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6TXA
 | | Crystal structure of tetrameric human D137N-SAMHD1 (residues 109-626) with XTP, dGMPNPP and Mg | | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ... | | Authors: | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A, Kelly, G, Taylor, I.A. | | Deposit date: | 2020-01-13 | | Release date: | 2020-06-24 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.853 Å) | | Cite: | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis.
Nat Commun, 11, 2020
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6TXE
 | | Crystal structure of tetrameric human wt-SAMHD1 (residues 109-626) with GTP, dATP, dTMPNPP and Mg | | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... | | Authors: | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | | Deposit date: | 2020-01-14 | | Release date: | 2020-06-24 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.19 Å) | | Cite: | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis.
Nat Commun, 11, 2020
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5DZY
 | | Protocadherin beta 8 extracellular cadherin domains 1-4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Pcdhb8 protein, ... | | Authors: | Goodman, K.M, Bahna, F, Mannepalli, S, Honig, B, Shapiro, L. | | Deposit date: | 2015-09-26 | | Release date: | 2016-05-04 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural Basis of Diverse Homophilic Recognition by Clustered alpha- and beta-Protocadherins.
Neuron, 90, 2016
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4BQE
 | | Arabidopsis thaliana Cytosolic Alpha-1,4-glucan Phosphorylase (PHS2) | | Descriptor: | ALPHA-GLUCAN PHOSPHORYLASE 2,4-GLUCAN PHOSPHORYLASE, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | O'Neill, E.C, Rashid, A.M, Stevenson, C.E.M, Hetru, A.C, Gunning, A.P, Rejzek, M, Nepogodiev, S.A, Bornemann, S, Lawson, D.M, Field, R.A. | | Deposit date: | 2013-05-30 | | Release date: | 2014-02-19 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Sugar-Coated Sensor Chip and Nanoparticle Surfaces for the in Vitro Enzymatic Synthesis of Starch-Like Materials
Chem.Sci., 5, 2014
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6E6B
 | | Crystal structure of the Protocadherin GammaB4 extracellular domain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Goodman, K.M, Mannepalli, S, Bahna, F, Honig, B, Shapiro, L. | | Deposit date: | 2018-07-24 | | Release date: | 2019-04-10 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (4.52 Å) | | Cite: | Visualization of clustered protocadherin neuronal self-recognition complexes.
Nature, 569, 2019
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4BQF
 | | Arabidopsis thaliana cytosolic alpha-1,4-glucan phosphorylase (PHS2) in complex with acarbose | | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC, ... | | Authors: | O'Neill, E.C, Rashid, A.M, Stevenson, C.E.M, Hetru, A.C, Gunning, A.P, Rejzek, M, Nepogodiev, S.A, Bornemann, S, Lawson, D.M, Field, R.A. | | Deposit date: | 2013-05-30 | | Release date: | 2014-02-19 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Sugar-Coated Sensor Chip and Nanoparticle Surfaces for the in Vitro Enzymatic Synthesis of Starch-Like Materials
Chem.Sci., 5, 2014
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4BQI
 | | ARABIDOPSIS THALIANA cytosolic alpha-1,4-glucan phosphorylase (PHS2) in complex with maltotriose | | Descriptor: | ALPHA-GLUCAN PHOSPHORYLASE 2, CYTOSOLIC, DI(HYDROXYETHYL)ETHER, ... | | Authors: | O'Neill, E.C, Rashid, A.M, Stevenson, C.E.M, Hetru, A.C, Gunning, A.P, Rejzek, M, Nepogodiev, S.A, Bornemann, S, Lawson, D.M, Field, R.A. | | Deposit date: | 2013-05-30 | | Release date: | 2014-02-19 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Sugar-Coated Sensor Chip and Nanoparticle Surfaces for the in Vitro Enzymatic Synthesis of Starch-Like Materials
Chem.Sci., 5, 2014
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8DJH
 | | Ternary complex of SUMO1 with a phosphomimetic SIM of PML and zinc | | Descriptor: | PML 4SD, Small ubiquitin-related modifier 1, ZINC ION | | Authors: | Lussier-Price, M, Wahba, H.M, Mascle, X.H, Cappadocia, L, Bourdeau, V, Gagnon, C, Igelmann, S, Sakaguchi, K, Ferbeyre, G, Omichinski, J.G. | | Deposit date: | 2022-06-30 | | Release date: | 2022-08-10 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.77 Å) | | Cite: | Zinc controls PML nuclear body formation through regulation of a paralog specific auto-inhibition in SUMO1.
Nucleic Acids Res., 50, 2022
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8DJI
 | | Ternary complex of SUMO1 with the SIM of PML and zinc | | Descriptor: | Protein PML, Small ubiquitin-related modifier 1, ZINC ION | | Authors: | Lussier-Price, M, Wahba, H.M, Mascle, X.H, Cappadocia, L, Bourdeau, V, Gagnon, C, Igelmann, S, Sakaguchi, K, Ferbeyre, G, Omichinski, J.G. | | Deposit date: | 2022-06-30 | | Release date: | 2022-08-10 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Zinc controls PML nuclear body formation through regulation of a paralog specific auto-inhibition in SUMO1.
Nucleic Acids Res., 50, 2022
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7XH9
 | | Crystal structure of a dimeric interlocked parallel G-quadruplex | | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*CP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION, STRONTIUM ION | | Authors: | Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T. | | Deposit date: | 2022-04-07 | | Release date: | 2023-02-15 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.63 Å) | | Cite: | Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A.G.G.G.G pentad in an interlocked G-quadruplex.
Biochem.Biophys.Res.Commun., 613, 2022
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7XHD
 | | Crystal structure of a dimeric interlocked parallel G-quadruplex | | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION | | Authors: | Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T. | | Deposit date: | 2022-04-08 | | Release date: | 2023-02-15 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A•G•G•G•G pentad in an interlocked G-quadruplex.
Biochem.Biophys.Res.Commun., 613, 2022
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7XIE
 | | Crystal structure of a dimeric interlocked parallel G-quadruplex | | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*GP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION | | Authors: | Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T. | | Deposit date: | 2022-04-13 | | Release date: | 2023-02-15 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A•G•G•G•G pentad in an interlocked G-quadruplex.
Biochem.Biophys.Res.Commun., 613, 2022
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7X7G
 | | Crystal structure of a dimeric interlocked parallel G-quadruplex | | Descriptor: | DNA (5'-D(*GP*GP*GP*GP*TP*GP*GP*GP*AP*GP*GP*TP*GP*GP*GP*T)-3'), POTASSIUM ION | | Authors: | Ngo, K.H, Liew, C.W, Lattmann, S, Winnerdy, F.R, Phan, A.T. | | Deposit date: | 2022-03-09 | | Release date: | 2022-04-20 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Crystal structures of an HIV-1 integrase aptamer: Formation of a water-mediated A.G.G.G.G pentad in an interlocked G-quadruplex.
Biochem.Biophys.Res.Commun., 613, 2022
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