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3WE4
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BU of 3we4 by Molmil
Crystal structure of S6K1 kinase domain in complex with a pyrimidine derivative PF-4708671 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole
Descriptor: 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole, Ribosomal protein S6 kinase beta-1, ZINC ION
Authors:Niwa, H, Shirouzu, M, Yokoyama, S.
Deposit date:2013-06-29
Release date:2014-08-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.995 Å)
Cite:Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3WU6
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BU of 3wu6 by Molmil
Oxidized E.coli Lon Proteolytic domain
Descriptor: Lon protease, SULFATE ION
Authors:Nishii, W, Kukimoto-Niino, M, Terada, T, Shirouzu, M, Muramatsu, T, Yokoyama, S.
Deposit date:2014-04-22
Release date:2014-11-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A redox switch shapes the Lon protease exit pore to facultatively regulate proteolysis.
Nat. Chem. Biol., 11, 2015
3WF7
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BU of 3wf7 by Molmil
Crystal structure of S6K1 kinase domain in complex with a purine derivative 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide
Descriptor: 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide, GLYCEROL, Ribosomal protein S6 kinase beta-1, ...
Authors:Niwa, H, Shirouzu, M, Yokoyama, S.
Deposit date:2013-07-17
Release date:2014-08-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3WF6
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BU of 3wf6 by Molmil
Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative 4-[4-(1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]-1H-pyrazolo[3,4-d]pyrimidine
Descriptor: 4-[4-(1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]-1H-pyrazolo[3,4-d]pyrimidine, Ribosomal protein S6 kinase beta-1, ZINC ION
Authors:Niwa, H, Shirouzu, M, Yokoyama, S.
Deposit date:2013-07-17
Release date:2014-08-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.031 Å)
Cite:Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3WF5
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BU of 3wf5 by Molmil
Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine
Descriptor: 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine, Ribosomal protein S6 kinase beta-1, ZINC ION
Authors:Niwa, H, Shirouzu, M, Yokoyama, S.
Deposit date:2013-07-17
Release date:2014-08-06
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
3WHE
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BU of 3whe by Molmil
A new conserved neutralizing epitope at the globular head of hemagglutinin in H3N2 influenza viruses
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Fujii, Y, Sumida, T, Shirouzu, M, Yokoyama, S.
Deposit date:2013-08-25
Release date:2014-04-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (4 Å)
Cite:Conserved neutralizing epitope at globular head of hemagglutinin in H3N2 influenza viruses.
J.Virol., 88, 2014
3WU5
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BU of 3wu5 by Molmil
Reduced E.coli Lon Proteolytic domain
Descriptor: Lon protease, SULFATE ION
Authors:Nishii, W, Kukimoto-Niino, M, Terada, T, Shirouzu, M, Muramatsu, T, Yokoyama, S.
Deposit date:2014-04-22
Release date:2014-11-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:A redox switch shapes the Lon protease exit pore to facultatively regulate proteolysis.
Nat. Chem. Biol., 11, 2015
3WF8
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BU of 3wf8 by Molmil
Crystal structure of S6K1 kinase domain in complex with a quinoline derivative 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carboxylate
Descriptor: 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carboxylate, GLYCEROL, Ribosomal protein S6 kinase beta-1, ...
Authors:Niwa, H, Shirouzu, M, Yokoyama, S.
Deposit date:2013-07-17
Release date:2014-08-06
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.975 Å)
Cite:Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
1WEH
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BU of 1weh by Molmil
Crystal structure of the conserved hypothetical protein TT1887 from Thermus thermophilus HB8
Descriptor: Conserved hypothetical protein TT1887
Authors:Kukimoto-Niino, M, Murayama, K, Idaka, M, Terada, T, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-25
Release date:2004-11-25
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures of possible lysine decarboxylases from Thermus thermophilus HB8
PROTEIN SCI., 13, 2004
3WU3
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BU of 3wu3 by Molmil
Reduced-form structure of E.coli Lon Proteolytic domain
Descriptor: Lon protease, SULFATE ION
Authors:Nishii, W, Kukimoto-Niino, M, Terada, T, Shirouzu, M, Muramatsu, T, Yokoyama, S.
Deposit date:2014-04-22
Release date:2014-11-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:A redox switch shapes the Lon protease exit pore to facultatively regulate proteolysis.
Nat. Chem. Biol., 11, 2015
3WF9
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BU of 3wf9 by Molmil
Crystal structure of S6K1 kinase domain in complex with a quinoline derivative 1-oxo-1-[(4-sulfamoylphenyl)amino]propan-2-yl-2-methyl-1,2,3,4-tetrahydroacridine-9-carboxylate
Descriptor: (2S)-1-oxo-1-[(4-sulfamoylphenyl)amino]propan-2-yl (2S)-2-methyl-1,2,3,4-tetrahydroacridine-9-carboxylate, GLYCEROL, Ribosomal protein S6 kinase beta-1, ...
Authors:Niwa, H, Shirouzu, M, Yokoyama, S.
Deposit date:2013-07-17
Release date:2014-08-06
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.035 Å)
Cite:Crystal structures of the S6K1 kinase domain in complexes with inhibitors
J.Struct.Funct.Genom., 15, 2014
1UG2
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BU of 1ug2 by Molmil
Solution Structure of Mouse Hypothetical Gene (2610100B20Rik) Product Homologous to Myb DNA-binding Domain
Descriptor: 2610100B20Rik gene product
Authors:Zhao, C, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Shirouzu, M, Terada, T, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Tanaka, A, Osanai, T, Arakawa, T, Carninci, P, Kawai, J, Hayashizaki, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-06-11
Release date:2004-06-22
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of Mouse Hypothetical Gene (2610100B20Rik) Product Homologous to Myb DNA-binding Domain
To be Published
3WU4
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BU of 3wu4 by Molmil
Oxidized-form structure of E.coli Lon Proteolytic domain
Descriptor: Lon protease, SULFATE ION
Authors:Nishii, W, Kukimoto-Niino, M, Terada, T, Shirouzu, M, Muramatsu, T, Yokoyama, S.
Deposit date:2014-04-22
Release date:2014-11-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A redox switch shapes the Lon protease exit pore to facultatively regulate proteolysis.
Nat. Chem. Biol., 11, 2015
1WD5
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BU of 1wd5 by Molmil
Crystal structure of TT1426 from Thermus thermophilus HB8
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, hypothetical protein TT1426
Authors:Shibata, R, Kukimoto-Niino, M, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-05-11
Release date:2004-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a predicted phosphoribosyltransferase (TT1426) from Thermus thermophilus HB8 at 2.01 A resolution
Protein Sci., 14, 2005
5XON
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BU of 5xon by Molmil
RNA Polymerase II elongation complex bound with Spt4/5 and TFIIS
Descriptor: DNA (48-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Ehara, H, Yokoyama, T, Shigematsu, H, Shirouzu, M, Sekine, S.
Deposit date:2017-05-29
Release date:2017-08-16
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.83 Å)
Cite:Structure of the complete elongation complex of RNA polymerase II with basal factors
Science, 357, 2017
1WRB
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BU of 1wrb by Molmil
Crystal structure of the N-terminal RecA-like domain of DjVLGB, a pranarian Vasa-like RNA helicase
Descriptor: DjVLGB, SULFATE ION
Authors:Kurimoto, K, Muto, Y, Obayashi, N, Terada, T, Shirouzu, M, Yabuki, T, Aoki, M, Seki, E, Matsuda, T, Kigawa, T, Okumura, H, Tanaka, A, Shibata, N, Kashikawa, M, Agata, K, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-10-14
Release date:2005-04-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of the N-terminal RecA-like domain of a DEAD-box RNA helicase, the Dugesia japonica vasa-like gene B protein
J.Struct.Biol., 150, 2005
2YT7
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BU of 2yt7 by Molmil
Solution structure of the PDZ domain of Amyloid beta A4 precursor protein-binding family A member 3
Descriptor: Amyloid beta A4 precursor protein-binding family A member 3
Authors:Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Tarada, T, Seiki, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-05
Release date:2008-04-15
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the PDZ domain of Amyloid beta A4 precursor protein-binding family A member 3
To be Published
1WMG
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BU of 1wmg by Molmil
Crystal structure of the UNC5H2 death domain
Descriptor: SULFATE ION, SULFITE ION, netrin receptor Unc5h2
Authors:Handa, N, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2004-07-09
Release date:2005-01-09
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the UNC5H2 death domain
ACTA CRYSTALLOGR.,SECT.D, 62, 2006
2YW5
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BU of 2yw5 by Molmil
Solution structure of the bromodomain from human bromodomain containing protein 3
Descriptor: Bromodomain-containing protein 3
Authors:Furue, M, Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-19
Release date:2008-04-22
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the bromodomain from human bromodomain containing protein 3
To be Published
1X4S
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BU of 1x4s by Molmil
Solution structure of zinc finger HIT domain in protein FON
Descriptor: ZINC ION, Zinc finger HIT domain containing protein 2
Authors:He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-14
Release date:2005-11-14
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the zinc finger HIT domain in protein FON
Protein Sci., 16, 2007
2Z0T
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BU of 2z0t by Molmil
Crystal structure of hypothetical protein PH0355
Descriptor: Putative uncharacterized protein PH0355
Authors:Murayama, K, Takemoto, C, Kato-Murayama, M, Kawazoe, M, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-07
Release date:2007-11-13
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of hypothetical protein PH0355
To be Published
2YZA
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BU of 2yza by Molmil
Crystal structure of kinase domain of Human 5'-AMP-activated protein kinase alpha-2 subunit mutant (T172D)
Descriptor: 5'-AMP-activated protein kinase catalytic subunit alpha-2
Authors:Saijo, S, Takagi, T, Yoshikawa, S, Kishishita, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-05-04
Release date:2008-05-06
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Structural basis for compound C inhibition of the human AMP-activated protein kinase alpha 2 subunit kinase domain
Acta Crystallogr.,Sect.D, 67, 2011
1WWH
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BU of 1wwh by Molmil
Crystal structure of the MPPN domain of mouse Nup35
Descriptor: nucleoporin 35
Authors:Handa, N, Murayama, K, Kukimoto, M, Hamana, H, Uchikubo, T, Takemoto, C, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-01-05
Release date:2005-07-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The crystal structure of mouse Nup35 reveals atypical RNP motifs and novel homodimerization of the RRM domain
J.Mol.Biol., 363, 2006
2ZDY
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BU of 2zdy by Molmil
Inhibitor-bound structures of human pyruvate dehydrogenase kinase 4
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kawamoto, M, Shiromizu, I, Kukimoto-Niino, M, Tokmakov, A, Terada, T, Shirouzu, M, Matsusue, T, Yokoyama, S.
Deposit date:2007-12-01
Release date:2008-12-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Inhibitor-bound structures of human pyruvate dehydrogenase kinase 4.
Acta Crystallogr.,Sect.D, 67, 2011
1UC8
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BU of 1uc8 by Molmil
Crystal structure of a lysine biosynthesis enzyme, Lysx, from thermus thermophilus HB8
Descriptor: lysine biosynthesis enzyme
Authors:Sakai, H, Vassylyeva, M.N, Matsuura, T, Sekine, S, Nishiyama, M, Terada, T, Shirouzu, M, Kuramitsu, S, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2003-04-09
Release date:2003-09-23
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of a Lysine Biosynthesis Enzyme, LysX, from Thermus thermophilus HB8
J.Mol.Biol., 332, 2003

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數據於2024-10-30公開中

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