7FDK
| SARS-COV-2 Spike RBDMACSp36 binding to mACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | Authors: | Wang, X, Cao, L. | Deposit date: | 2021-07-16 | Release date: | 2021-08-25 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.69 Å) | Cite: | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2. Nat Commun, 12, 2021
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7FDH
| SARS-COV-2 Spike RBDMACSp25 binding to hACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | Authors: | Wang, X, Cao, L. | Deposit date: | 2021-07-16 | Release date: | 2021-08-25 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2. Nat Commun, 12, 2021
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7FDI
| SARS-COV-2 Spike RBDMACSp36 binding to hACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | Authors: | Wang, X, Cao, L. | Deposit date: | 2021-07-16 | Release date: | 2021-08-25 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2. Nat Commun, 12, 2021
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7FDG
| SARS-COV-2 Spike RBDMACSp6 binding to hACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S1 | Authors: | Wang, X, Cao, L. | Deposit date: | 2021-07-16 | Release date: | 2021-08-25 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.69 Å) | Cite: | Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2. Nat Commun, 12, 2021
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7VV9
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7VVG
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7VV8
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7VVB
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7X5H
| Serotonin 5A (5-HT5A) receptor-Gi protein complex | Descriptor: | 3-(2-azanylethyl)-1H-indole-5-carboxamide, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Tan, Y, Xu, P, Huang, S, Xu, H.E, Jiang, Y. | Deposit date: | 2022-03-04 | Release date: | 2022-09-14 | Last modified: | 2022-09-21 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into the ligand binding and G i coupling of serotonin receptor 5-HT 5A . Cell Discov, 8, 2022
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5Z31
| LPS bound solution structure of WS2-KG18 | Descriptor: | LYS-ASN-LYS-SER-ARG-VAL-ALA-ARG-GLY-TRP-GLY-ARG-LYS-CYS-PRO-LEU-PHE-GLY | Authors: | Bhunia, A, Mohid, S.A. | Deposit date: | 2018-01-05 | Release date: | 2019-02-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Application of tungsten disulfide quantum dot-conjugated antimicrobial peptides in bio-imaging and antimicrobial therapy. Colloids Surf B Biointerfaces, 176, 2019
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5Z32
| LPS bound solution NMR structure of WS2-VR18 | Descriptor: | VAL-ALA-ARG-GLY-TRP-GLY-ARG-LYS-CYS-PRO-LEU-PHE-GLY-LYS-ASN-LYS-SER-ARG | Authors: | Bhunia, A, Mohid, S.A. | Deposit date: | 2018-01-05 | Release date: | 2019-02-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Application of tungsten disulfide quantum dot-conjugated antimicrobial peptides in bio-imaging and antimicrobial therapy. Colloids Surf B Biointerfaces, 176, 2019
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4P6L
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4P6J
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4EWO
| Design and synthesis of potent hydroxyethylamine (hea) bace-1 inhibitors | Descriptor: | Beta-secretase 1, N-[(2S,3R)-4-{[(4S)-2-(2,2-dimethylpropyl)-6,6-dimethyl-4,5,6,7-tetrahydro-2H-indazol-4-yl]amino}-3-hydroxy-1-phenylbutan-2-yl]acetamide | Authors: | Borkakoti, N, Lindberg, J, Derbyshire, D. | Deposit date: | 2012-04-27 | Release date: | 2012-10-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Design and synthesis of potent hydroxyethylamine (HEA) BACE-1 inhibitors carrying prime side 4,5,6,7-tetrahydrobenzazole and 4,5,6,7-tetrahydropyridinoazole templates. Bioorg.Med.Chem.Lett., 22, 2012
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4EXG
| Design and synthesis of potent hydroxyethylamine (hea) bace-1 inhibitors | Descriptor: | Beta-secretase 1, N-[(2S,3R)-4-{[(4S)-6-(2,2-dimethylpropyl)-2,2-dimethyl-3,4-dihydro-2H-thieno[2,3-b]pyran-4-yl]amino}-3-hydroxy-1-phenylbutan-2-yl]acetamide | Authors: | Borkakoti, N, Lindberg, J, Derbyshire, D. | Deposit date: | 2012-04-30 | Release date: | 2012-10-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Design and synthesis of potent hydroxyethylamine (HEA) BACE-1 inhibitors carrying prime side 4,5,6,7-tetrahydrobenzazole and 4,5,6,7-tetrahydropyridinoazole templates. Bioorg.Med.Chem.Lett., 22, 2012
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4P6K
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8IM7
| Human gamma-secretase treated with ganglioside GM1 | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Zhou, R, Yang, G, Shi, Y. | Deposit date: | 2023-03-06 | Release date: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Preferential Regulation of Gamma-Secretase-Mediated Cleavage of APP by Ganglioside GM1 Reveals a Potential Therapeutic Target for Alzheimer's Disease. Adv Sci, 10, 2023
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5T2U
| short chain dehydrogenase/reductase family protein | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Oxidoreductase, short chain dehydrogenase/reductase family protein | Authors: | Mickael, B, Van Wyk, N, Baneres-Roquet, F, Yann, G, Laurent, K. | Deposit date: | 2016-08-24 | Release date: | 2017-02-15 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Binding of NADP(+) triggers an open-to-closed transition in a mycobacterial FabG beta-ketoacyl-ACP reductase. Biochem. J., 474, 2017
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2MUZ
| ssNMR structure of a designed rocker protein | Descriptor: | designed rocker protein | Authors: | Wang, T, Joh, N, Wu, Y, DeGrado, W.F, Hong, M. | Deposit date: | 2014-09-18 | Release date: | 2014-12-24 | Last modified: | 2015-01-14 | Method: | SOLUTION NMR | Cite: | De novo design of a transmembrane Zn2+-transporting four-helix bundle. Science, 346, 2014
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