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7T0O
cryoEM reconstruction of the HIV gp140 in complex with the extracellular domains of CD4 and the adnectin domain of Combinectin. The gp140 and CD4 coordinates from entry 6EDU were rigid body fitted to the EM map along withe the crystal structure of CD4+adnectin
Descriptor:
Adnectin, BG505 SOSIP.664 gp140, T-cell surface glycoprotein CD4
Authors:
Concha, N.O
,
William, S.P
,
Wenzel, D.L.
Deposit date:
2021-11-30
Release date:
2022-01-12
Method:
ELECTRON MICROSCOPY (8.7 Å)
Cite:
Novel Bent Conformation of CD4 Induced by HIV-1 Inhibitor Indirectly Prevents Productive Viral Attachment.
J.Mol.Biol., 434, 2021
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数据于2024-07-24公开中