8EO2
| Lufaxin a bifunctional inhibitor of complement and coagulation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, ... | Authors: | Andersen, J.F, Strayer, E.C. | Deposit date: | 2022-10-01 | Release date: | 2023-08-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism. Blood, 141, 2023
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6XKE
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6XL7
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6XMB
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8UIN
| Structure of the C3bBb-albicin complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Albicin, ... | Authors: | Andersen, J.F, Lei, H. | Deposit date: | 2023-10-10 | Release date: | 2024-05-08 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Mechanism of complement inhibition by a mosquito protein revealed through cryo-EM. Commun Biol, 7, 2024
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8ENU
| Structure of the C3bB proconvertase in complex with lufaxin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3 beta chain, Complement C3b alpha' chain, ... | Authors: | Andersen, J.F, Lei, H. | Deposit date: | 2022-09-30 | Release date: | 2023-08-09 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.22 Å) | Cite: | A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism. Blood, 141, 2023
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8EOK
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