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7RB1
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BU of 7rb1 by Molmil
Isocitrate Lyase-1 from Mycobacterium tuberculosis covalently modified by 5-descarboxy-5-nitro-D-isocitric acid
Descriptor: (3E)-3-(hydroxyimino)propanoic acid, GLYCEROL, GLYOXYLIC ACID, ...
Authors:Krieger, I.V, Mellott, D, Meek, T, Sacchettini, J.C.
Deposit date:2021-07-05
Release date:2021-12-01
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism-Based Inactivation of Mycobacterium tuberculosis Isocitrate Lyase 1 by (2 R ,3 S )-2-Hydroxy-3-(nitromethyl)succinic acid.
J.Am.Chem.Soc., 143, 2021
6WSI
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BU of 6wsi by Molmil
Intact cis-2,3-epoxysuccinic acid bound to Isocitrate Lyase-1 from Mycobacterium tuberculosis
Descriptor: (2R,3S)-oxirane-2,3-dicarboxylic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Krieger, I.V, Mellott, D, Meek, T.D, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2020-05-01
Release date:2021-03-24
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.749 Å)
Cite:Covalent Inactivation of Mycobacterium tuberculosis Isocitrate Lyase by cis -2,3-Epoxy-Succinic Acid.
Acs Chem.Biol., 16, 2021

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数据于2024-11-13公开中

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