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Structure of the trypanosome brucei factor H receptor bound to domain D5 of bovine factor H
Descriptor:	Complement factor H, GARP domain-containing protein
Authors:	Macleod, O.J.S, Carrington, M, Higgins, M.K.
Deposit date:	2020-02-02
Release date:	2020-03-25
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (2.7 Å)
Cite:	A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies. Nat Commun, 11, 2020

Trypanosoma brucei ISG65 bound to human complement C3d
Descriptor:	2-(2-METHOXYETHOXY)ETHANOL, 65 kDa invariant surface glycoprotein, Complement C3dg fragment, ...
Authors:	Cook, A.D, Higgins, M.K.
Deposit date:	2021-08-19
Release date:	2022-07-27
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (2.6 Å)
Cite:	Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor. Nat Commun, 13, 2022

Trypanosoma brucei transferrin receptor in complex with human transferrin
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, ESAG6, subunit of heterodimeric transferrin receptor, ...
Authors:	Trevor, C, Carrington, M, Higgins, M.K.
Deposit date:	2019-08-30
Release date:	2019-11-06
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.75 Å)
Cite:	Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion. Nat Microbiol, 4, 2019

Glycosylated Trypanosoma brucei transferrin receptor in complex with human transferrin
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ESAG6, ...
Authors:	Trevor, C, Carrington, M, Higgins, M.K.
Deposit date:	2019-08-30
Release date:	2019-11-06
Last modified:	2024-10-16
Method:	X-RAY DIFFRACTION (3.42 Å)
Cite:	Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion. Nat Microbiol, 4, 2019