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1FZX
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BU of 1fzx by Molmil
NMR SOLUTION STRUCTURE OF THE DNA DODECAMER GGCAAAAAACGG
Descriptor: 5'-D(*CP*CP*GP*TP*TP*TP*TP*TP*TP*GP*CP*C)-3', 5'-D(*GP*GP*CP*AP*AP*AP*AP*AP*AP*CP*GP*G)-3'
Authors:MacDonald, D, Herbert, K, Zhang, X, Pologruto, T, Lu, P.
Deposit date:2000-10-04
Release date:2001-03-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of an A-tract DNA bend.
J.Mol.Biol., 306, 2001
1G14
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BU of 1g14 by Molmil
NMR SOLUTION STRUCTURE OF THE DNA DODECAMER GGCAAGAAACGG
Descriptor: 5'-D(*CP*CP*GP*TP*TP*TP*CP*TP*TP*GP*CP*C)-3', 5'-D(*GP*GP*CP*AP*AP*GP*AP*AP*AP*CP*GP*G)-3'
Authors:MacDonald, D, Herbert, K, Zhang, X, Pologruto, T, Lu, P.
Deposit date:2000-10-10
Release date:2001-03-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of an A-tract DNA bend.
J.Mol.Biol., 306, 2001
2A3V
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BU of 2a3v by Molmil
Structural basis for broad DNA-specificity in integron recombination
Descriptor: DNA (31-MER), DNA (34-MER), site-specific recombinase IntI4
Authors:MacDonald, D, Demarre, G, Bouvier, M, Mazel, D, Gopaul, D.N.
Deposit date:2005-06-27
Release date:2006-05-02
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for broad DNA-specificity in integron recombination.
Nature, 440, 2006
2FM5
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BU of 2fm5 by Molmil
Crystal structure of PDE4D2 in complex with inhibitor L-869299
Descriptor: (R)-3-(2-(3-CYCLOPROPOXY-4-(DIFLUOROMETHOXY)PHENYL)-2-(5-(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL)THIAZOL-2-YL)ETHYL)PYRIDINE 1-OXIDE, MAGNESIUM ION, ZINC ION, ...
Authors:Huai, Q, Sun, Y, Wang, H, Macdonald, D, Aspiotis, R, Robinson, H, Huang, Z, Ke, H.
Deposit date:2006-01-07
Release date:2006-03-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Enantiomer Discrimination Illustrated by the High Resolution Crystal Structures of Type 4 Phosphodiesterase
J.Med.Chem., 49, 2006
2FM0
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Crystal structure of PDE4D in complex with L-869298
Descriptor: (S)-3-(2-(3-CYCLOPROPOXY-4-(DIFLUOROMETHOXY)PHENYL)-2-(5-(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL)THIAZOL-2-YL)ETHY L)PYRIDINE 1-OXIDE, MAGNESIUM ION, ZINC ION, ...
Authors:Huai, Q, Sun, Y, Wang, H, Macdonald, D, Aspiotis, R, Robinson, H, Huang, Z, Ke, H.
Deposit date:2006-01-06
Release date:2006-03-28
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Enantiomer Discrimination Illustrated by the High Resolution Crystal Structures of Type 4 Phosphodiesterase
J.Med.Chem., 49, 2006
8FJB
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CryoEM structure of HLA-A2 MAGEA4 (286-294) in complex with H2aM31345N Fab
Descriptor: Beta-2-microglobulin, H2aM31345N Fab heavy chain, H2aM31345N Fab light chain, ...
Authors:Saotome, K, Franklin, M.C.
Deposit date:2022-12-19
Release date:2023-12-20
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:CAR T cells based on fully human T cell receptor-mimetic antibodies exhibit potent antitumor activity in vivo.
Sci Transl Med, 17, 2025
8FJA
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CryoEM structure of HLA-A2 MAGEA4 (230-239) in complex with REGN6972 Fab
Descriptor: Beta-2-microglobulin, MHC class I antigen, Melanoma-associated antigen 4 peptide, ...
Authors:Saotome, K, Franklin, M.C.
Deposit date:2022-12-19
Release date:2023-12-20
Last modified:2025-05-21
Method:ELECTRON MICROSCOPY (3 Å)
Cite:CAR T cells based on fully human T cell receptor-mimetic antibodies exhibit potent antitumor activity in vivo.
Sci Transl Med, 17, 2025
6PYD
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BU of 6pyd by Molmil
Structure of 3E9 antibody Fab bound to marinobufagenin
Descriptor: (3beta,5beta,14alpha,15beta)-3,5-dihydroxy-14,15-epoxybufa-20,22-dienolide, 3E9 anti-marinobufagenin antibody Fab heavy chain, recloned with human IgG4 C region, ...
Authors:Franklin, M.C, Macdonald, L.E, McWhirter, J, Murphy, A.J.
Deposit date:2019-07-29
Release date:2019-12-25
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties.
Proc.Natl.Acad.Sci.USA, 117, 2020
6PYC
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Structure of kappa-on-heavy (KoH) antibody Fab bound to the cardiac hormone marinobufagenin
Descriptor: (3beta,5beta,14alpha,15beta)-3,5-dihydroxy-14,15-epoxybufa-20,22-dienolide, KoH body Fab heavy chain, KoH body Fab light chain, ...
Authors:Franklin, M.C, Macdonald, L.E, McWhirter, J, Murphy, A.J.
Deposit date:2019-07-29
Release date:2019-12-25
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties.
Proc.Natl.Acad.Sci.USA, 117, 2020
7QI1
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BU of 7qi1 by Molmil
Crystal structure of human 14-3-3 protein beta in complex with CFTR peptide pS753pS768 and PPI stabilizer CY007424
Descriptor: 14-3-3 protein theta, ARGININE, Cystic fibrosis transmembrane conductance regulator, ...
Authors:Stevers, L.M, Ottmann, C.
Deposit date:2021-12-14
Release date:2022-05-25
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR.
Nat Commun, 13, 2022

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数据于2025-07-09公开中

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