7QYF
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![BU of 7qyf by Molmil](/molmil-images/mine/7qyf) | Structure of the transaminase PluriZyme variant (TR2E2) | Descriptor: | Aminotransferase TR2 | Authors: | Roda, S, Fernandez-Lopez, L, Benedens, M, Bollinger, A, Thies, S, Schumacher, J, Coscolin, C, Kazemi, M, Santiago, G, Gertzen, C.G, Gonzalez-Alfonso, J, Plou, F.J, Jaeger, K.E, Smits, S.H, Ferrer, M, Guallar, V. | Deposit date: | 2022-01-28 | Release date: | 2023-07-26 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions. Angew Chem Int Ed Engl, 61, 2022
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7QX3
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![BU of 7qx3 by Molmil](/molmil-images/mine/7qx3) | Structure of the transaminase TR2E2 with EOS | Descriptor: | 2-azanylethyl hydrogen sulfate, Aminotransferase TR2 | Authors: | Roda, S, Fernandez-Lopez, L, Benedens, M, Bollinger, A, Thies, S, Schumacher, J, Coscolin, C, Kazemi, M, Santiago, G, Gertzen, C.G, Gonzalez-Alfonso, J, Plou, F.J, Jaeger, K.E, Smits, S.H, Ferrer, M, Guallar, V. | Deposit date: | 2022-01-26 | Release date: | 2023-08-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions. Angew.Chem.Int.Ed.Engl., 61, 2022
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7QX0
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![BU of 7qx0 by Molmil](/molmil-images/mine/7qx0) | Transaminase Structure of Plurienzyme (Tr2E2) in complex with PLP | Descriptor: | Aminotransferase TR2, PYRIDOXAL-5'-PHOSPHATE | Authors: | Roda, S, Fernandez-Lopez, L, Benedens, M, Bollinger, A, Thies, S, Schumacher, J, Coscolin, C, Kazemi, M, Santiago, G, Gertzen, C.G, Gonzalez-Alfonso, J, Plou, F.J, Jaeger, K.E, Smits, S.H, Ferrer, M, Guallar, V. | Deposit date: | 2022-01-26 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions. Angew Chem Int Ed Engl, 61, 2022
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7QYG
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![BU of 7qyg by Molmil](/molmil-images/mine/7qyg) | Structure of the transaminase TR2 | Descriptor: | Aminotransferase TR2 | Authors: | Roda, S, Fernandez-Lopez, L, Benedens, M, Bollinger, A, Thies, S, Schumacher, J, Coscolin, C, Kazemi, M, Santiago, G, Gertzen, C.G, Gonzalez-Alfonso, J, Plou, F.J, Jaeger, K.E, Smits, S.H, Ferrer, M, Guallar, V. | Deposit date: | 2022-01-28 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | A Plurizyme with Transaminase and Hydrolase Activity Catalyzes Cascade Reactions. Angew Chem Int Ed Engl, 61, 2022
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3I2V
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![BU of 3i2v by Molmil](/molmil-images/mine/3i2v) | Crystal structure of human MOCS3 rhodanese-like domain | Descriptor: | Adenylyltransferase and sulfurtransferase MOCS3 | Authors: | Bacik, J.P, Walker, J.R, Lopez, L, Li, Y, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-06-29 | Release date: | 2009-07-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Crystal structure of the human MOCS3 rhodanese-like domain To be Published
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8CIQ
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![BU of 8ciq by Molmil](/molmil-images/mine/8ciq) | JzTx-34 toxin peptide | Descriptor: | Mu-theraphotoxin-Cg1a | Authors: | Landon, C, Meudal, H. | Deposit date: | 2023-02-10 | Release date: | 2023-07-26 | Method: | SOLUTION NMR | Cite: | Structure-function relationship of new peptides activating human Na v 1.1. Biomed Pharmacother, 165, 2023
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8CJP
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![BU of 8cjp by Molmil](/molmil-images/mine/8cjp) | JzTx-34 toxin peptide H18A mutant | Descriptor: | Mu-theraphotoxin-Cg1a | Authors: | Landon, C, Meudal, H. | Deposit date: | 2023-02-13 | Release date: | 2023-07-26 | Method: | SOLUTION NMR | Cite: | Structure-function relationship of new peptides activating human Na v 1.1. Biomed Pharmacother, 165, 2023
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8CJS
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![BU of 8cjs by Molmil](/molmil-images/mine/8cjs) | JzTx-34 toxin peptide W31A mutant | Descriptor: | Mu-theraphotoxin-Cg1a | Authors: | Landon, C, Meudal, H. | Deposit date: | 2023-02-13 | Release date: | 2023-07-26 | Method: | SOLUTION NMR | Cite: | Structure-function relationship of new peptides activating human Na v 1.1. Biomed Pharmacother, 165, 2023
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8CJQ
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![BU of 8cjq by Molmil](/molmil-images/mine/8cjq) | JzTx-34 toxin peptide E20A mutant | Descriptor: | Mu-theraphotoxin-Cg1a | Authors: | Landon, C, Meudal, H. | Deposit date: | 2023-02-13 | Release date: | 2023-07-26 | Method: | SOLUTION NMR | Cite: | Structure-function relationship of new peptides activating human Na v 1.1. Biomed Pharmacother, 165, 2023
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8CJR
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![BU of 8cjr by Molmil](/molmil-images/mine/8cjr) | JzTx-34 toxin peptide W25A mutant | Descriptor: | Mu-theraphotoxin-Cg1a | Authors: | Landon, C, Meudal, H. | Deposit date: | 2023-02-13 | Release date: | 2023-07-26 | Method: | SOLUTION NMR | Cite: | Structure-function relationship of new peptides activating human Na v 1.1. Biomed Pharmacother, 165, 2023
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8CJT
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![BU of 8cjt by Molmil](/molmil-images/mine/8cjt) | JzTx-34 toxin peptide W33A mutant | Descriptor: | Mu-theraphotoxin-Cg1a | Authors: | Landon, C, Meudal, H. | Deposit date: | 2023-02-13 | Release date: | 2023-07-26 | Method: | SOLUTION NMR | Cite: | Structure-function relationship of new peptides activating human Na v 1.1. Biomed Pharmacother, 165, 2023
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7M7V
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![BU of 7m7v by Molmil](/molmil-images/mine/7m7v) | Crystal Structure of Mtb Pks13 Thioesterase domain in complex with Compound 6 | Descriptor: | 5-hydroxy-2-(4-hydroxyphenyl)-N-methyl-4-[(2-oxa-6-azaspiro[3.4]octan-6-yl)methyl]-1-benzofuran-3-carboxamide, Polyketide synthase Pks13 | Authors: | Aggarwal, A, Sacchettini, J.C. | Deposit date: | 2021-03-29 | Release date: | 2022-02-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target. J.Med.Chem., 65, 2022
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6RB0
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![BU of 6rb0 by Molmil](/molmil-images/mine/6rb0) | |
6RKY
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![BU of 6rky by Molmil](/molmil-images/mine/6rky) | |
8PC7
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![BU of 8pc7 by Molmil](/molmil-images/mine/8pc7) | |
7QI8
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![BU of 7qi8 by Molmil](/molmil-images/mine/7qi8) | CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM Mycobacterium tuberculosis COMPLEXED WITH L-LYSINE AND INHIBITOR | Descriptor: | 2-azanyl-6-[(1~{S},7~{S})-2,2-bis(fluoranyl)-7-oxidanyl-cycloheptyl]-4-methoxy-7~{H}-pyrrolo[3,4-d]pyrimidin-5-one, LYSINE, Lysine--tRNA ligase 1 | Authors: | Dawson, A, Robinson, D.A, Tamjar, J, Wyatt, P, Green, S. | Deposit date: | 2021-12-14 | Release date: | 2022-10-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs. Nat Commun, 13, 2022
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7QHN
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![BU of 7qhn by Molmil](/molmil-images/mine/7qhn) | CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM Mycobacterium tuberculosis COMPLEXED WITH L-LYSINE and an inhibitor | Descriptor: | 6-azanyl-2-cyclohexyl-4-fluoranyl-1~{H}-pyrrolo[3,4-c]pyridin-3-one, LYSINE, Lysine--tRNA ligase 1 | Authors: | Dawson, A, Robinson, D.A, Tamjar, J, Wyatt, P, Green, S. | Deposit date: | 2021-12-13 | Release date: | 2022-10-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.58 Å) | Cite: | Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs. Nat Commun, 13, 2022
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7QH8
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![BU of 7qh8 by Molmil](/molmil-images/mine/7qh8) | CRYSTAL STRUCTURE OF LYSYL-TRNA SYNTHETASE FROM Mycobacterium tuberculosis COMPLEXED WITH L-LYSINE | Descriptor: | GLYCEROL, LYSINE, Lysine--tRNA ligase 1 | Authors: | Dawson, A, Robinson, D.A, Tamjar, J, Wyatt, P, Green, S. | Deposit date: | 2021-12-10 | Release date: | 2022-10-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs. Nat Commun, 13, 2022
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6I8F
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![BU of 6i8f by Molmil](/molmil-images/mine/6i8f) | |
7ALZ
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![BU of 7alz by Molmil](/molmil-images/mine/7alz) | GqqA- a novel type of quorum quenching acylases | Descriptor: | PHENYLALANINE, Prephenate dehydratase | Authors: | Werner, N, Betzel, C. | Deposit date: | 2020-10-07 | Release date: | 2021-08-04 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | The Komagataeibacter europaeus GqqA is the prototype of a novel bifunctional N-Acyl-homoserine lactone acylase with prephenate dehydratase activity. Sci Rep, 11, 2021
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7AM0
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![BU of 7am0 by Molmil](/molmil-images/mine/7am0) | GqqA- a novel type of quorum quenching acylases | Descriptor: | PHENYLALANINE, Prephenate dehydratase | Authors: | Werner, N, Betzel, C. | Deposit date: | 2020-10-07 | Release date: | 2021-08-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Komagataeibacter europaeus GqqA is the prototype of a novel bifunctional N-Acyl-homoserine lactone acylase with prephenate dehydratase activity. Sci Rep, 11, 2021
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