1M5R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1m5r by Molmil](/molmil-images/mine/1m5r) | Ternary complex of T4 phage BGT with UDP and a 13 mer DNA duplex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*CP*TP*AP*TP*CP*TP*GP*AP*GP*TP*AP*TP*C)-3', ... | Authors: | Lariviere, L, Morera, S. | Deposit date: | 2002-07-10 | Release date: | 2002-12-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A Base-flipping mechanism for the T4 phage beta-glucosyltransferase and
identification of a transition state analog J.Mol.Biol., 324, 2002
|
|
3C0T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3c0t by Molmil](/molmil-images/mine/3c0t) | Structure of the Schizosaccharomyces pombe Mediator subcomplex Med8C/18 | Descriptor: | Mediator of RNA polymerase II transcription subunit 18, Mediator of RNA polymerase II transcription subunit 8 | Authors: | Lariviere, L, Seizl, M, van Wageningen, S, Roether, S, van de Pasch, L, Feldmann, H, Straesser, K, Hahn, S, Holstege, C.P, Cramer, P. | Deposit date: | 2008-01-21 | Release date: | 2008-04-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure-system correlation identifies a gene regulatory Mediator submodule Genes Dev., 22, 2008
|
|
1SXP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sxp by Molmil](/molmil-images/mine/1sxp) | BGT in complex with a 13mer DNA containing a central A:G mismatch | Descriptor: | 5'-D(*A*AP*TP*AP*CP*TP*AP*AP*GP*AP*TP*AP*G)-3', 5'-D(*CP*TP*AP*TP*CP*TP*GP*AP*GP*TP*AP*TP*T)-3', DNA beta-glucosyltransferase, ... | Authors: | Lariviere, L, Morera, S. | Deposit date: | 2004-03-31 | Release date: | 2004-06-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural evidence of a passive base flipping mechanism for {beta}-Glucosyltransferase J.Biol.Chem., 279, 2004
|
|
1SXQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sxq by Molmil](/molmil-images/mine/1sxq) | |
4H62
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4h62 by Molmil](/molmil-images/mine/4h62) | Structure of the Saccharomyces cerevisiae Mediator subcomplex Med17C/Med11C/Med22C | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, ... | Authors: | Lariviere, L, Plaschka, C, Seizl, M, Wenzeck, L, Kurth, F, Cramer, P. | Deposit date: | 2012-09-19 | Release date: | 2012-10-31 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of the Mediator head module. Nature, 492, 2012
|
|
4H61
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4h61 by Molmil](/molmil-images/mine/4h61) | Structure of the Schizosaccharomyces pombe Mediator subunit Med6 | Descriptor: | Mediator of RNA polymerase II transcription subunit 6 | Authors: | Lariviere, L, Plaschka, C, Seizl, M, Wenzeck, L, Kurth, F, Cramer, P. | Deposit date: | 2012-09-19 | Release date: | 2012-10-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of the Mediator head module. Nature, 492, 2012
|
|
4H63
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4h63 by Molmil](/molmil-images/mine/4h63) | Structure of the Schizosaccharomyces pombe Mediator head module | Descriptor: | Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 17, Mediator of RNA polymerase II transcription subunit 18, ... | Authors: | Lariviere, L, Plaschka, C, Seizl, M, Wenzeck, L, Kurth, F, Cramer, P. | Deposit date: | 2012-09-19 | Release date: | 2012-10-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structure of the Mediator head module. Nature, 492, 2012
|
|
1NZD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nzd by Molmil](/molmil-images/mine/1nzd) | T4 phage BGT-D100A mutant in complex with UDP-glucose: Form I | Descriptor: | CHLORIDE ION, DNA beta-glycosyltransferase, GLYCEROL, ... | Authors: | Lariviere, L, Morera, S. | Deposit date: | 2003-02-17 | Release date: | 2003-09-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the T4 phage beta-glucosyltransferase and the D100A mutant in complex with UDP-glucose: glucose binding and identification of the catalytic base for a direct displacement mechanism J.Mol.Biol., 330, 2003
|
|
1NVK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nvk by Molmil](/molmil-images/mine/1nvk) | T4 phage BGT in complex with UDP and a Mn2+ ion at 1.8 A resolution | Descriptor: | DNA beta-glucosyltransferase, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Lariviere, L, Kurzeck, J, Gueguen-Chaignon, V, Rueger, W, Morera, S. | Deposit date: | 2003-02-04 | Release date: | 2003-09-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of the T4 phage beta-glucosyltransferase and the D100A mutant in complex with UDP-glucose: glucose binding and identification of the catalytic base for a direct displacement mechanism J.Mol.Biol., 330, 2003
|
|
1NZF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nzf by Molmil](/molmil-images/mine/1nzf) | T4 phage BGT-D100A mutant in complex with UDP-glucose: Form II | Descriptor: | CHLORIDE ION, DNA beta-glycosyltransferase, GLYCEROL, ... | Authors: | Lariviere, L, Morera, S. | Deposit date: | 2003-02-17 | Release date: | 2003-09-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of the T4 phage beta-glucosyltransferase and the D100A mutant in complex with
UDP-glucose: glucose binding and identification of the catalytic base for a direct displacement mechanism. J.Mol.Biol., 330, 2003
|
|
2HZS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hzs by Molmil](/molmil-images/mine/2hzs) | Structure of the Mediator head submodule Med8C/18/20 | Descriptor: | RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20, RNA polymerase II mediator complex subunit 8 | Authors: | Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P. | Deposit date: | 2006-08-09 | Release date: | 2006-09-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20. Nat.Struct.Mol.Biol., 13, 2006
|
|
1IXY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ixy by Molmil](/molmil-images/mine/1ixy) | Ternary complex of T4 phage BGT with UDP and a 13 mer DNA duplex | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5'-D(*CP*TP*AP*TP*CP*TP*GP*AP*GP*TP*AP*TP*C)-3', 5'-D(*GP*AP*TP*AP*CP*TP*3DRP*AP*GP*AP*TP*AP*G)-3', ... | Authors: | Lariviere, L, Morera, S. | Deposit date: | 2002-07-09 | Release date: | 2002-12-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A Base-flipping Mechanism for the T4 Phage beta-Glucosyltransferase and Identification of a
Transition-state Analog J.Mol.Biol., 324, 2002
|
|
2HZM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hzm by Molmil](/molmil-images/mine/2hzm) | Structure of the Mediator head subcomplex Med18/20 | Descriptor: | PHOSPHATE ION, RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20 | Authors: | Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P. | Deposit date: | 2006-08-09 | Release date: | 2006-09-12 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20. Nat.Struct.Mol.Biol., 13, 2006
|
|
1Y8Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1y8z by Molmil](/molmil-images/mine/1y8z) | alpha-glucosyltransferase in complex with UDP and a 13-mer DNA containing a HMU base at 1.9 A resolution | Descriptor: | 5'-D(*CP*TP*AP*TP*CP*TP*GP*AP*G)-3', 5'-D(*GP*AP*TP*AP*CP*TP*(5HU)P*AP*GP*AP*TP*AP*G)-3', CHLORIDE ION, ... | Authors: | Lariviere, L, Sommer, N, Morera, S. | Deposit date: | 2004-12-14 | Release date: | 2005-08-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural evidence of a passive base-flipping mechanism for AGT, an unusual GT-B glycosyltransferase. J.Mol.Biol., 352, 2005
|
|
1XV5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1xv5 by Molmil](/molmil-images/mine/1xv5) | alpha-glucosyltransferase (AGT) in complex with UDP | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DNA alpha-glucosyltransferase, ... | Authors: | Lariviere, L, Sommer, N, Morera, S. | Deposit date: | 2004-10-27 | Release date: | 2005-08-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Structural evidence of a passive base-flipping mechanism for AGT, an unusual GT-B glycosyltransferase. J.Mol.Biol., 352, 2005
|
|
1YA6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ya6 by Molmil](/molmil-images/mine/1ya6) | alpha-glucosyltransferase in complex with UDP and a 13-mer DNA containing a central A:G mismatch | Descriptor: | 5'-D(*AP*TP*AP*CP*TP*AP*AP*GP*AP*TP*AP*G)-3', 5'-D(*CP*TP*AP*TP*CP*TP*GP*AP*GP*TP*AP*T)-3', COBALT HEXAMMINE(III), ... | Authors: | Lariviere, L, Sommer, N, Morera, S. | Deposit date: | 2004-12-17 | Release date: | 2005-08-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural evidence of a passive base-flipping mechanism for AGT, an unusual GT-B glycosyltransferase. J.Mol.Biol., 352, 2005
|
|
1Y6G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1y6g by Molmil](/molmil-images/mine/1y6g) | alpha-glucosyltransferase in complex with UDP and a 13_mer DNA containing a HMU base at 2.8 A resolution | Descriptor: | 1,2-ETHANEDIOL, 5'-D(*CP*TP*AP*TP*CP*TP*GP*AP*GP*TP*AP*T)-3', 5'-D(*GP*AP*TP*AP*CP*TP*(5HU)P*AP*GP*AP*TP*AP*G)-3', ... | Authors: | Lariviere, L, Sommer, N, Morera, S. | Deposit date: | 2004-12-06 | Release date: | 2005-08-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural evidence of a passive base-flipping mechanism for AGT, an unusual GT-B glycosyltransferase. J.Mol.Biol., 352, 2005
|
|
1Y6F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1y6f by Molmil](/molmil-images/mine/1y6f) | alpha-glucosyltransferase in complex with UDP-glucose and DNA containing an abasic site | Descriptor: | 5'-D(*CP*TP*AP*TP*CP*TP*GP*AP*GP*TP*AP*TP*C)-3', 5'-D(*GP*AP*TP*AP*CP*TP*(3DR)P*AP*GP*AP*TP*AP*G)-3', DI(HYDROXYETHYL)ETHER, ... | Authors: | Lariviere, L, Sommer, N, Morera, S. | Deposit date: | 2004-12-06 | Release date: | 2005-08-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural evidence of a passive base-flipping mechanism for AGT, an unusual GT-B glycosyltransferase. J.Mol.Biol., 352, 2005
|
|
1J39
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1j39 by Molmil](/molmil-images/mine/1j39) | Crystal Structure of T4 phage BGT in complex with its UDP-glucose substrate | Descriptor: | DNA beta-glucosyltransferase, GLYCEROL, URIDINE-5'-DIPHOSPHATE-GLUCOSE | Authors: | Lariviere, L, Morera, S. | Deposit date: | 2003-01-21 | Release date: | 2003-08-19 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Crystal structures of the T4 phage beta-glucosyltransferase and the D100A mutant in complex with UDP-glucose: glucose binding and identification of the catalytic base for a direct displacement mechanism. J.Mol.Biol., 330, 2003
|
|
4V1N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v1n by Molmil](/molmil-images/mine/4v1n) | Architecture of the RNA polymerase II-Mediator core transcription initiation complex | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | Authors: | Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. | Deposit date: | 2014-09-29 | Release date: | 2015-02-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
|
|
4V1M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v1m by Molmil](/molmil-images/mine/4v1m) | Architecture of the RNA polymerase II-Mediator core transcription initiation complex | Descriptor: | 5'-D(*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', 5'-D(*CP*CP*AP*GP*GP*AP)-3', 5'-D(*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP*TP*TP*CP *CP*BRUP*GP*GP*TP*C)-3', ... | Authors: | Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. | Deposit date: | 2014-09-29 | Release date: | 2015-02-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
|
|
4V1O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4v1o by Molmil](/molmil-images/mine/4v1o) | Architecture of the RNA polymerase II-Mediator core transcription initiation complex | Descriptor: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | Authors: | Plaschka, C, Lariviere, L, Wenzeck, L, Hemann, M, Tegunov, D, Petrotchenko, E.V, Borchers, C.H, Baumeister, W, Herzog, F, Villa, E, Cramer, P. | Deposit date: | 2014-09-29 | Release date: | 2015-02-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (9.7 Å) | Cite: | Architecture of the RNA Polymerase II-Mediator Core Initiation Complex. Nature, 518, 2015
|
|
3R84
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3r84 by Molmil](/molmil-images/mine/3r84) | Structure of the Mediator head subcomplex Med11/22 | Descriptor: | Mediator of RNA polymerase II transcription subunit 11, Mediator of RNA polymerase II transcription subunit 22 | Authors: | Seizl, M, Lariviere, L, Pfaffenender, T, Wenzeck, L, Cramer, P. | Deposit date: | 2011-03-23 | Release date: | 2011-04-27 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Mediator head subcomplex Med11/22 contains a common helix bundle building block with a specific function in transcription initiation complex stabilization. Nucleic Acids Res., 39, 2011
|
|
2AK7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ak7 by Molmil](/molmil-images/mine/2ak7) | structure of a dimeric P-Ser-Crh | Descriptor: | HPr-like protein crh, SULFATE ION | Authors: | Chaptal, V, Gueguen-Chaignon, V, Poncet, S, Lecampion, C, Lariviere, L, Meyer, P, Galinier, A, Deutscher, J, Nessler, S, Morera, S. | Deposit date: | 2005-08-03 | Release date: | 2006-06-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structure of a domain-swapped dimer of Ser46-phosphorylated Crh from Bacillus subtilis. Proteins, 63, 2006
|
|
2XNF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xnf by Molmil](/molmil-images/mine/2xnf) | The Mediator Med25 activator interaction domain: Structure and cooperative binding of VP16 subdomains | Descriptor: | MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 | Authors: | Vojnic, E, Mourao, A, Seizl, M, Simon, B, Wenzeck, L, Lariviere, L, Baumli, S, Meisterernst, M, Sattler, M, Cramer, P. | Deposit date: | 2010-08-02 | Release date: | 2011-03-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure and Vp16 Binding of the Mediator Med25 Activator Interaction Domain. Nat.Struct.Mol.Biol., 18, 2011
|
|