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Drug resistant cSrc kinase domain in complex with covalent inhibitor PD168393
Descriptor:	N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE, Proto-oncogene tyrosine-protein kinase Src
Authors:	Gruetter, C, Rode, H.B, Rauh, D.
Deposit date:	2010-02-04
Release date:	2010-12-22
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.48 Å)
Cite:	Characterization of irreversible kinase inhibitors by directly detecting covalent bond formation: a tool for dissecting kinase drug resistance Chembiochem, 11, 2010

Kinase domain of cSrc in complex with inhibitor RL37 (Type III)
Descriptor:	1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-phenylurea, Proto-oncogene tyrosine-protein kinase Src
Authors:	Gruetter, C, Klueter, S, Getlik, M, Rauh, D.
Deposit date:	2008-10-31
Release date:	2009-03-03
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	A new screening assay for allosteric inhibitors of cSrc Nat.Chem.Biol., 5, 2009

Kinase domain of cSrc in complex with inhibitor RL38 (Type III)
Descriptor:	1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea, Proto-oncogene tyrosine-protein kinase Src
Authors:	Gruetter, C, Klueter, S, Getlik, M, Rauh, D.
Deposit date:	2008-10-31
Release date:	2009-03-03
Last modified:	2023-11-01
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	A new screening assay for allosteric inhibitors of cSrc Nat.Chem.Biol., 5, 2009