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8Y1J
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BU of 8y1j by Molmil
Structure of the pyridoxal 5'-phosphate-dependent (PLP) threonine deaminase ilvA1 from Pseudomonas aeruginosa PAO1
Descriptor: 2-KETOBUTYRIC ACID, L-threonine dehydratase
Authors:Jia, H, Bartlam, M.
Deposit date:2024-01-24
Release date:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and function of the pyridoxal 5'-phosphate-dependent (PLP) threonine deaminase IlvA1 from Pseudomonas aeruginosa PAO1.
Biochem.Biophys.Res.Commun., 704, 2024
7V1J
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BU of 7v1j by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and m7GpppA)
Descriptor: Core protein, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1B
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BU of 7v1b by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH)
Descriptor: CITRIC ACID, Core protein, ISOPROPYL ALCOHOL, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1H
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BU of 7v1h by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAM and m7GTP)
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, CITRIC ACID, Core protein, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1D
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BU of 7v1d by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and GpppA)
Descriptor: Core protein, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1I
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BU of 7v1i by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (with an m7GMP-Arg28 adduct and in complex with SAH)
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Core protein, GLYCEROL, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1G
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BU of 7v1g by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (with a GMP-Arg28 adduct and in complex with SAM)
Descriptor: CITRIC ACID, Core protein, GLYCEROL, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1C
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BU of 7v1c by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SIN)
Descriptor: Core protein, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1E
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BU of 7v1e by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAH and m7GpppAmG)
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE, Core protein, GLYCEROL, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7V1F
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BU of 7v1f by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAM and GTP)
Descriptor: Core protein, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
7E7G
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BU of 7e7g by Molmil
2-aminoethylphosphonate:pyruvate aminotransferase (AEPT) native
Descriptor: 2-aminoethylphosphonate--pyruvate transaminase
Authors:Jia, H, Zhang, Q, Bartlam, M.
Deposit date:2021-02-26
Release date:2021-03-31
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural characterization of a 2-aminoethylphosphonate:pyruvate aminotransferase from Pseudomonas aeruginosa PAO1.
Biochem.Biophys.Res.Commun., 552, 2021
7FJT
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BU of 7fjt by Molmil
Crystal structure of Omsk hemorrhagic fever virus NS5 MTase (in complex with SAM)
Descriptor: CITRIC ACID, Core protein, GLYCEROL, ...
Authors:Jia, H, Gong, P.
Deposit date:2021-08-04
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal Structures of Flavivirus NS5 Guanylyltransferase Reveal a GMP-Arginine Adduct.
J.Virol., 96, 2022
6LXK
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BU of 6lxk by Molmil
Crystal structure of Z2B3 D102R Fab in complex with influenza virus neuraminidase from A/Serbia/NS-601/2014 (H1N1)
Descriptor: CALCIUM ION, Heavy chain of Z2B3-D102R Fab, Light chain of Z2B3-D102R Fab, ...
Authors:Jiang, H, Peng, W, Qi, J, Chai, Y, Song, H, Shi, Y, Gao, G.F, Wu, Y.
Deposit date:2020-02-11
Release date:2020-12-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.608 Å)
Cite:Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus.
Mbio, 11, 2020
6LXJ
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BU of 6lxj by Molmil
Crystal structure of human Z2B3 Fab in complex with influenza virus neuraminidase from A/Anhui/1/2013 (H7N9)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Heavy chain of Z2B3 Fab, ...
Authors:Jiang, H, Peng, W, Qi, J, Chai, Y, Song, H, Shi, Y, Gao, G.F, Wu, Y.
Deposit date:2020-02-11
Release date:2020-12-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.903 Å)
Cite:Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus.
Mbio, 11, 2020
6LXI
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BU of 6lxi by Molmil
Crystal structure of Z2B3 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1)
Descriptor: CALCIUM ION, Heavy chain of Z2B3 Fab, Light chain of Z2B3 Fab, ...
Authors:Jiang, H, Peng, W, Qi, J, Chai, Y, Song, H, Shi, Y, Gao, G.F, Wu, Y.
Deposit date:2020-02-11
Release date:2020-12-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-Based Modification of an Anti-neuraminidase Human Antibody Restores Protection Efficacy against the Drifted Influenza Virus.
Mbio, 11, 2020
7WZC
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BU of 7wzc by Molmil
An open conformation Form2 of switch II for RhoA GDP-bound state
Descriptor: GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Jiang, H, Luo, C.
Deposit date:2022-02-17
Release date:2023-02-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.79944921 Å)
Cite:A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region.
J.Struct.Biol., 215, 2023
7WZA
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BU of 7wza by Molmil
An open conformation Form 1 of switch II for RhoA
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA
Authors:Jiang, H, Luo, C.
Deposit date:2022-02-17
Release date:2023-02-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.50028777 Å)
Cite:A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region.
J.Struct.Biol., 215, 2023
5Y1Y
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BU of 5y1y by Molmil
Complex structure of nitroxoline with the first bromodomain of BRD4
Descriptor: 5-nitroquinolin-8-ol, Bromodomain-containing protein 4
Authors:Jiang, H, Luo, C.
Deposit date:2017-07-21
Release date:2017-11-15
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.912 Å)
Cite:Discovery of novel BET inhibitors by drug repurposing of nitroxoline and its analogues.
Org. Biomol. Chem., 15, 2017
7CPD
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BU of 7cpd by Molmil
Crystal structure of T2R-TTL-(+)-6-Br-JP18 complex
Descriptor: (6R)-6-[(6-bromanyl-1H-indol-3-yl)methyl]-6,7,8,9-tetrahydrobenzo[7]annulen-5-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Jiang, H, Luo, C.
Deposit date:2020-08-06
Release date:2021-08-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.506 Å)
Cite:Crystal structure of T2R-TTL-(+)-6-Br-JP18 complex
To Be Published
7CPQ
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BU of 7cpq by Molmil
crystal structure of T2R-TTL-(+)-6-Cl-JP18 complex
Descriptor: (6R)-6-[(6-chloranyl-1H-indol-3-yl)methyl]-6,7,8,9-tetrahydrobenzo[7]annulen-5-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
Authors:Jiang, H, Luo, C.
Deposit date:2020-08-07
Release date:2021-08-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.595 Å)
Cite:crystal structure of T2R-TTL-(+)-6-Cl-JP18 complex
To Be Published
7E9F
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BU of 7e9f by Molmil
Cryo-EM structure of the 2:1 Orc1 BAH domain in complex with nucleosome
Descriptor: DNA (147-mer), Histone H2A.2, Histone H2B.2, ...
Authors:Jiang, H, Yu, C, Liu, C.P, Han, X, Yu, Z, Xu, R.M.
Deposit date:2021-03-04
Release date:2022-09-07
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Nucleosome binding relinquishes the association of the BAH domain of Orc1 with Sir1
To Be Published
7E9C
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BU of 7e9c by Molmil
Cryo-EM structure of the 1:1 Orc1 BAH domain in complex with nucleosome
Descriptor: DNA (147-mer), Histone H2A.2, Histone H2B.2, ...
Authors:Jiang, H, Yu, C, Liu, C.P, Han, X, Yu, Z, Xu, R.M.
Deposit date:2021-03-04
Release date:2022-09-07
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Nucleosome binding relinquishes the association of the BAH domain of Orc1 with Sir1
To Be Published
8FRE
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BU of 8fre by Molmil
Designed loop protein RBL4
Descriptor: 1,2-ETHANEDIOL, RBL4
Authors:Jude, K.M, Jiang, H, Baker, D, Garcia, K.C.
Deposit date:2023-01-06
Release date:2024-04-17
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:De novo design of buttressed loops for sculpting protein functions.
Nat.Chem.Biol., 2024
8FRF
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BU of 8frf by Molmil
Homodimeric designed loop protein RBL7_C2_3
Descriptor: MALONATE ION, RBL7_C2_3
Authors:Jude, K.M, Jiang, H, Baker, D, Garcia, K.C.
Deposit date:2023-01-06
Release date:2024-04-17
Last modified:2024-06-26
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:De novo design of buttressed loops for sculpting protein functions.
Nat.Chem.Biol., 2024
7Y7I
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BU of 7y7i by Molmil
chicken KNL2 in complex with the CENP-A nucleosome
Descriptor: Chains: I, Chains: J, Histone H2A type 1-B/E, ...
Authors:Ariyoshi, M, Jiang, H, Makino, F, Fukagawa, T.
Deposit date:2022-06-22
Release date:2022-07-13
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:The cryo-EM structure of the CENP-A nucleosome in complex with ggKNL2.
Biorxiv, 2022

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数据于2024-07-10公开中

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