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Cruzain covalently bound by a vinylsulfone compound
Descriptor:	Cruzipain, GLYCEROL, Nalpha-[(benzyloxy)carbonyl]-N-[(2S)-1-phenyl-4-(phenylsulfonyl)butan-2-yl]-L-phenylalaninamide
Authors:	Zhai, X, Tang, S, Chenna, B.C, Meek, T.D, Sacchettini, J.C.
Deposit date:	2019-11-06
Release date:	2020-11-25
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.94 Å)
Cite:	Cruzain covalently bound by a vinylsulfone compound To Be Published

Crystal Structure of T. cruzi DHFR-TS with 3 high affinity DHFR inhibitors: DQ1 inhibitor complex
Descriptor:	1,2-ETHANEDIOL, Dihydrofolate reductase-thymidylate synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:	Schormann, N, Senkovich, O, Chattopadhyay, D.
Deposit date:	2009-11-03
Release date:	2010-06-09
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.5 Å)
Cite:	Synthesis and characterization of potent inhibitors of Trypanosoma cruzi dihydrofolate reductase. Bioorg.Med.Chem., 18, 2010

Structure of the SARS-CoV-2 3CL protease in complex with inhibitor 18
Descriptor:	3C-like proteinase, Inhibitor 18 in bound form
Authors:	Yang, K, Li, L.
Deposit date:	2021-03-17
Release date:	2021-08-25
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Self-Masked Aldehyde Inhibitors: A Novel Strategy for Inhibiting Cysteine Proteases. J.Med.Chem., 64, 2021