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5ICV
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BU of 5icv by Molmil
Crystal structure of human NatF (hNaa60) bound to a bisubstrate analogue
Descriptor: MET-LYS-ALA-VAL-LIG, N-alpha-acetyltransferase 60, [5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)furan-2-yl]methyl (3R)-4-{[3-({(E)-2-[(2,2-dihydroxyethyl)sulfanyl]ethenyl}amino)-3-oxopropyl]amino}-3-hydroxy-2,2-dimethyl-4-oxobutyl dihydrogen diphosphate
Authors:Stove, S.I, Magin, R.S, Marmorstein, R, Arnesen, T.
Deposit date:2016-02-23
Release date:2016-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Crystal Structure of the Golgi-Associated Human N alpha-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation.
Structure, 24, 2016
5WJD
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BU of 5wjd by Molmil
Crystal structure of Naa80 bound to acetyl-CoA
Descriptor: ACETYL COENZYME *A, CG8481, isoform B, ...
Authors:Goris, M, Magin, R.S, Marmorstein, R, Arnesen, T.
Deposit date:2017-07-21
Release date:2018-03-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5ICW
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BU of 5icw by Molmil
Crystal structure of human NatF (hNaa60) homodimer bound to Coenzyme A
Descriptor: CHLORIDE ION, COENZYME A, N-alpha-acetyltransferase 60
Authors:Stove, S.I, Magin, R.S, Marmorstein, R, Arnesen, T.
Deposit date:2016-02-23
Release date:2016-06-22
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:Crystal Structure of the Golgi-Associated Human N alpha-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation.
Structure, 24, 2016
5WJE
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BU of 5wje by Molmil
Crystal structure of Naa80 bound to a bisubstrate analogue
Descriptor: Actin N-terminus peptide, CARBOXYMETHYL COENZYME *A, CG8481, ...
Authors:Goris, M, Magin, R.S, Marmorstein, R, Arnesen, T.
Deposit date:2017-07-21
Release date:2018-03-28
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.765 Å)
Cite:Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3TFY
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BU of 3tfy by Molmil
Naa50p amino-terminal acetyltransferase bound to substrate peptide fragment and CoA
Descriptor: COENZYME A, N-alpha-acetyltransferase 50, NatE catalytic subunit, ...
Authors:Liszczak, G.P, Marmorstein, R.
Deposit date:2011-08-16
Release date:2011-09-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of a Ternary Naa50p (NAT5/SAN) N-terminal Acetyltransferase Complex Reveals the Molecular Basis for Substrate-specific Acetylation.
J.Biol.Chem., 286, 2011
6PPL
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BU of 6ppl by Molmil
Cryo-EM structure of human NatE complex (NatA/Naa50)
Descriptor: ACETYL COENZYME *A, INOSITOL HEXAKISPHOSPHATE, N-alpha-acetyltransferase 10, ...
Authors:Deng, S, Marmorstein, R.
Deposit date:2019-07-08
Release date:2020-02-19
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK.
Nat Commun, 11, 2020
6PW9
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BU of 6pw9 by Molmil
Cryo-EM structure of human NatE/HYPK complex
Descriptor: ACETYL COENZYME *A, Huntingtin-interacting protein K, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Deng, S, Marmorstein, R.
Deposit date:2019-07-22
Release date:2020-02-19
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (4.03 Å)
Cite:Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK.
Nat Commun, 11, 2020
6NBE
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BU of 6nbe by Molmil
Ternary Complex of Ac-Alpha-Actin with Profilin and CoA-NAA80
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2018-12-07
Release date:2020-04-15
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
6NBW
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BU of 6nbw by Molmil
Ternary Complex of Beta/Gamma-Actin with Profilin and AnCoA-NAA80
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2018-12-10
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
6NAS
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BU of 6nas by Molmil
Ternary Complex of Ac-Alpha-Actin with Profilin and AcCoA-NAA80
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETYL COENZYME *A, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Rebowski, G, Boczkowska, M, Dominguez, R.
Deposit date:2018-12-06
Release date:2020-01-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism of actin N-terminal acetylation.
Sci Adv, 6, 2020
4KVO
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BU of 4kvo by Molmil
The NatA (Naa10p/Naa15p) amino-terminal acetyltrasferase complex bound to AcCoA
Descriptor: ACETYL COENZYME *A, CHLORIDE ION, N-terminal acetyltransferase A complex catalytic subunit ard1, ...
Authors:Liszczak, G.P, Marmorstein, R.Q.
Deposit date:2013-05-22
Release date:2013-07-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Molecular basis for N-terminal acetylation by the heterodimeric NatA complex.
Nat.Struct.Mol.Biol., 20, 2013
4KVM
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BU of 4kvm by Molmil
The NatA (Naa10p/Naa15p) amino-terminal acetyltransferase complex bound to a bisubstrate analog
Descriptor: CHLORIDE ION, N-terminal acetyltransferase A complex catalytic subunit ard1, N-terminal acetyltransferase A complex subunit nat1, ...
Authors:Liszczak, G.P, Marmorstein, R.Q.
Deposit date:2013-05-22
Release date:2013-07-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.597 Å)
Cite:Molecular basis for N-terminal acetylation by the heterodimeric NatA complex.
Nat.Struct.Mol.Biol., 20, 2013
4KVX
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BU of 4kvx by Molmil
Crystal structure of Naa10 (Ard1) bound to AcCoA
Descriptor: ACETYL COENZYME *A, N-terminal acetyltransferase A complex catalytic subunit ard1
Authors:Liszczak, G.P, Marmorstein, R.Q.
Deposit date:2013-05-23
Release date:2013-07-31
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular basis for N-terminal acetylation by the heterodimeric NatA complex.
Nat.Struct.Mol.Biol., 20, 2013
8PI9
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BU of 8pi9 by Molmil
DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -181G>A)
Descriptor: Chains: E, Chains: F, Hepatocyte nuclear factor 1-alpha
Authors:Kind, L, Myllykoski, M, Raasakka, A, Kursula, P.
Deposit date:2023-06-21
Release date:2024-06-19
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes.
JCI Insight, 9, 2024
8PI7
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BU of 8pi7 by Molmil
DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -169C>T)
Descriptor: CHLORIDE ION, Chains: E, Chains: F, ...
Authors:Kind, L, Myllykoski, M, Raasakka, A, Kursula, P.
Deposit date:2023-06-21
Release date:2024-06-19
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes.
JCI Insight, 9, 2024
8PI8
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BU of 8pi8 by Molmil
DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA
Descriptor: Chains: E, Chains: F, GLYCEROL, ...
Authors:Kind, L, Myllykoski, M, Raasakka, A, Kursula, P.
Deposit date:2023-06-21
Release date:2024-06-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes.
JCI Insight, 9, 2024
8PIA
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BU of 8pia by Molmil
DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -181G>T)
Descriptor: Chains: E, Chains: F, GLYCEROL, ...
Authors:Kind, L, Myllykoski, M, Raasakka, A, Kursula, P.
Deposit date:2023-06-21
Release date:2024-06-19
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes.
JCI Insight, 9, 2024

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数据于2024-11-06公开中

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