2ZK5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zk5 by Molmil](/molmil-images/mine/2zk5) | Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed with nitro-233 | Descriptor: | 3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Waku, T, Shiraki, T, Oyama, T, Fujimoto, Y, Morikawa, K. | Deposit date: | 2008-03-12 | Release date: | 2009-02-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids J.Mol.Biol., 385, 2009
|
|
2ZMF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zmf by Molmil](/molmil-images/mine/2zmf) | Crystal structure of the C-terminal GAF domain of human phosphodiesterase 10A | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | Authors: | Handa, N, Kishishita, S, Mizohata, E, Omori, K, Kotera, J, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2008-04-17 | Release date: | 2008-04-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of the GAF-B Domain from Human Phosphodiesterase 10A Complexed with Its Ligand, cAMP J.Biol.Chem., 283, 2008
|
|
2ZE0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ze0 by Molmil](/molmil-images/mine/2ze0) | Alpha-glucosidase GSJ | Descriptor: | Alpha-glucosidase, CALCIUM ION | Authors: | Shirai, T, Hung, V.S, Morinaka, K, Kobayashi, T, Ito, S. | Deposit date: | 2007-12-04 | Release date: | 2007-12-18 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of GH13 alpha-glucosidase GSJ from one of the deepest sea bacteria Proteins, 73, 2008
|
|
5ZR0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zr0 by Molmil](/molmil-images/mine/5zr0) | Solution structure of peptidyl-prolyl cis/trans isomerase domain of Trigger Factor in complex with MBP | Descriptor: | Maltose-binding periplasmic protein,Trigger factor | Authors: | Kawagoe, S, Nakagawa, H, Kumeta, H, Ishimori, K, Saio, T. | Deposit date: | 2018-04-21 | Release date: | 2018-08-22 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structural insight into prolinecis/transisomerization of unfolded proteins catalyzed by the trigger factor chaperone. J. Biol. Chem., 293, 2018
|
|
4XSM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xsm by Molmil](/molmil-images/mine/4xsm) | Crystal structure of D-tagatose 3-epimerase C66S from Pseudomonas cichorii in complex with D-talitol | Descriptor: | D-altritol, D-tagatose 3-epimerase, MANGANESE (II) ION | Authors: | Yoshida, H, Yoshihara, A, Ishii, T, Izumori, K, Kamitori, S. | Deposit date: | 2015-01-22 | Release date: | 2016-01-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | X-ray structures of the Pseudomonas cichorii D-tagatose 3-epimerase mutant form C66S recognizing deoxy sugars as substrates Appl. Microbiol. Biotechnol., 100, 2016
|
|
3AN3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3an3 by Molmil](/molmil-images/mine/3an3) | Human PPAR gamma ligand binding domain in complex with a gamma selective agonist MO3S | Descriptor: | (2S)-2-benzyl-3-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}phenyl)propanoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Oyama, T, Ohashi, M, Waku, T, Miyachi, H, Morikawa, K. | Deposit date: | 2010-08-30 | Release date: | 2011-07-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPAR gamma-Selective Agonists: Discovery of Reversed Stereochemistry-Activity Relationship J.Med.Chem., 54, 2011
|
|
3AN4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3an4 by Molmil](/molmil-images/mine/3an4) | Human PPAR gamma ligand binding domain in complex with a gamma selective agonist MO4R | Descriptor: | (2R)-2-benzyl-3-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}phenyl)propanoic acid, Peroxisome proliferator-activated receptor gamma | Authors: | Oyama, T, Ohashi, M, Waku, T, Miyachi, H, Morikawa, K. | Deposit date: | 2010-08-30 | Release date: | 2011-07-27 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPAR gamma-Selective Agonists: Discovery of Reversed Stereochemistry-Activity Relationship J.Med.Chem., 54, 2011
|
|
4XSL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xsl by Molmil](/molmil-images/mine/4xsl) | Crystal strcutre of D-tagatose 3-epimerase C66S from Pseudomonas cichorii in complex with glycerol | Descriptor: | D-tagatose 3-epimerase, GLYCEROL, MANGANESE (II) ION | Authors: | Yoshida, H, Yoshihara, A, Ishii, T, Izumori, K, Kamitori, S. | Deposit date: | 2015-01-22 | Release date: | 2016-01-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | X-ray structures of the Pseudomonas cichorii D-tagatose 3-epimerase mutant form C66S recognizing deoxy sugars as substrates Appl. Microbiol. Biotechnol., 100, 2016
|
|
4Z2N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4z2n by Molmil](/molmil-images/mine/4z2n) | Crystal structure of human FACT SPT16 middle domain | Descriptor: | FACT complex subunit SPT16 | Authors: | Tsunaka, Y, Fujiwara, Y, Oyama, T, Hirose, S, Morikawa, K. | Deposit date: | 2015-03-30 | Release date: | 2016-03-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.923 Å) | Cite: | Integrated molecular mechanism directing nucleosome reorganization by human FACT. Genes Dev., 30, 2016
|
|
4Z2M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4z2m by Molmil](/molmil-images/mine/4z2m) | Crystal structure of human SPT16 Mid-AID/H3-H4 tetramer FACT Histone complex | Descriptor: | FACT complex subunit SPT16, Histone H3.1, Histone H4 | Authors: | Tsunaka, Y, Fujiwara, Y, Oyama, T, Hirose, S, Morikawa, K. | Deposit date: | 2015-03-30 | Release date: | 2016-03-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.981 Å) | Cite: | Integrated molecular mechanism directing nucleosome reorganization by human FACT. Genes Dev., 30, 2016
|
|
1VSR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1vsr by Molmil](/molmil-images/mine/1vsr) | VERY SHORT PATCH REPAIR (VSR) ENDONUCLEASE FROM ESCHERICHIA COLI | Descriptor: | PROTEIN (VSR ENDONUCLEASE), ZINC ION | Authors: | Tsutakawa, S.E, Muto, T, Jingami, H, Kunishima, N, Ariyoshi, M, Kohda, D, Nakagawa, M, Morikawa, K. | Deposit date: | 1999-02-13 | Release date: | 1999-10-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystallographic and functional studies of very short patch repair endonuclease. Mol.Cell, 3, 1999
|
|
1WXL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wxl by Molmil](/molmil-images/mine/1wxl) | Solution Structure of the HMG-box domain in the SSRP1 subunit of FACT | Descriptor: | Single-strand recognition protein | Authors: | Kasai, N, Tsunaka, Y, Ohki, I, Hirose, S, Morikawa, K, Tate, S. | Deposit date: | 2005-01-26 | Release date: | 2005-08-16 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the HMG-box domain in the SSRP1 subunit of FACT J.Biomol.Nmr, 32, 2005
|
|
7D7M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7d7m by Molmil](/molmil-images/mine/7d7m) | Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein | Descriptor: | (Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl]hept-5-enoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Nojima, S, Fujita, Y, Kimura, T.K, Nomura, N, Suno, R, Morimoto, K, Yamamoto, M, Noda, T, Iwata, S, Shigematsu, H, Kobayashi, T. | Deposit date: | 2020-10-05 | Release date: | 2020-11-18 | Last modified: | 2021-03-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein. Structure, 29, 2021
|
|
2E4Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2e4z by Molmil](/molmil-images/mine/2e4z) | Crystal structure of the ligand-binding region of the group III metabotropic glutamate receptor | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Metabotropic glutamate receptor 7 | Authors: | Muto, T, Tsuchiya, D, Morikawa, K, Jingami, H. | Deposit date: | 2006-12-17 | Release date: | 2007-02-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structures of the extracellular regions of the group II/III metabotropic glutamate receptors Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2EGK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2egk by Molmil](/molmil-images/mine/2egk) | Crystal Structure of Tamalin PDZ-Intrinsic Ligand Fusion Protein | Descriptor: | General receptor for phosphoinositides 1-associated scaffold protein, PHOSPHATE ION | Authors: | Sugi, T, Oyama, T, Muto, T, Nakanishi, S, Morikawa, K, Jingami, H. | Deposit date: | 2007-03-01 | Release date: | 2007-05-08 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal structures of autoinhibitory PDZ domain of Tamalin: implications for metabotropic glutamate receptor trafficking regulation Embo J., 26, 2007
|
|
2E4W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2e4w by Molmil](/molmil-images/mine/2e4w) | Crystal structure of the extracellular region of the group II metabotropic glutamate receptor complexed with 1S,3S-ACPD | Descriptor: | (1S,3S)-1-aminocyclopentane-1,3-dicarboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 3 | Authors: | Muto, T, Tsuchiya, D, Morikawa, K, Jingami, H. | Deposit date: | 2006-12-17 | Release date: | 2007-02-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of the extracellular regions of the group II/III metabotropic glutamate receptors Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2E4V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2e4v by Molmil](/molmil-images/mine/2e4v) | Crystal structure of the extracellular region of the group II metabotropic glutamate receptor complexed with DCG-IV | Descriptor: | (1R,2R)-3-[(S)-amino(carboxy)methyl]cyclopropane-1,2-dicarboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Metabotropic glutamate receptor 3 | Authors: | Muto, T, Tsuchiya, D, Morikawa, K, Jingami, H. | Deposit date: | 2006-12-17 | Release date: | 2007-02-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of the extracellular regions of the group II/III metabotropic glutamate receptors Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2EGO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ego by Molmil](/molmil-images/mine/2ego) | Crystal Structure of Tamalin PDZ Domain | Descriptor: | General receptor for phosphoinositides 1-associated scaffold protein | Authors: | Sugi, T, Oyama, T, Muto, T, Nakanishi, S, Morikawa, K, Jingami, H. | Deposit date: | 2007-03-01 | Release date: | 2007-05-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of autoinhibitory PDZ domain of Tamalin: implications for metabotropic glutamate receptor trafficking regulation Embo J., 26, 2007
|
|
1HJP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1hjp by Molmil](/molmil-images/mine/1hjp) | HOLLIDAY JUNCTION BINDING PROTEIN RUVA FROM E. COLI | Descriptor: | RUVA | Authors: | Nishino, T, Ariyoshi, M, Iwasaki, H, Shinagawa, H, Morikawa, K. | Deposit date: | 1997-08-21 | Release date: | 1998-02-25 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Functional Analyses of the Domain Structure in the Holliday Junction Binding Protein Ruva Structure, 6, 1998
|
|
1IZ4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1iz4 by Molmil](/molmil-images/mine/1iz4) | |
1IXZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ixz by Molmil](/molmil-images/mine/1ixz) | Crystal structure of the FtsH ATPase domain from Thermus thermophilus | Descriptor: | ATP-dependent metalloprotease FtsH, MERCURY (II) ION, SULFATE ION | Authors: | Niwa, H, Tsuchiya, D, Makyio, H, Yoshida, M, Morikawa, K. | Deposit date: | 2002-07-10 | Release date: | 2002-11-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Hexameric ring structure of the ATPase domain of the membrane-integrated metalloprotease FtsH from Thermus thermophilus HB8 Structure, 10, 2002
|
|
2HCV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hcv by Molmil](/molmil-images/mine/2hcv) | Crystal structure of L-rhamnose isomerase from Pseudomonas stutzeri with metal ion | Descriptor: | L-rhamnose isomerase, ZINC ION | Authors: | Yoshida, H, Yamada, M, Takada, G, Izumori, K, Kamitori, S. | Deposit date: | 2006-06-19 | Release date: | 2006-12-19 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Structures of l-Rhamnose Isomerase from Pseudomonas stutzeri in Complexes with l-Rhamnose and d-Allose Provide Insights into Broad Substrate Specificity J.Mol.Biol., 365, 2007
|
|
1IY2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1iy2 by Molmil](/molmil-images/mine/1iy2) | Crystal structure of the FtsH ATPase domain from Thermus thermophilus | Descriptor: | ATP-dependent metalloprotease FtsH, SULFATE ION | Authors: | Niwa, H, Tsuchiya, D, Makyio, H, Yoshida, M, Morikawa, K. | Deposit date: | 2002-07-10 | Release date: | 2002-11-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Hexameric ring structure of the ATPase domain of the membrane-integrated metalloprotease FtsH from Thermus thermophilus HB8 Structure, 10, 2002
|
|
1G3Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1g3q by Molmil](/molmil-images/mine/1g3q) | |
1G3R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1g3r by Molmil](/molmil-images/mine/1g3r) | |