7FJS
 
 | | Crystal structure of T6 Fab bound to theSARS-CoV-2 RBD of B.1.351 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, T6 heavy chain, ... | | Authors: | Wang, X, Zhang, L, Zhang, S, Liang, Q. | | Deposit date: | 2021-08-04 | | Release date: | 2022-04-27 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants.
Iscience, 25, 2022
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7FJN
 | | Cryo-EM structure of South African (B.1.351) SARS-CoV-2 spike glycoprotein in complex with two T6 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Envelope glycoprotein, T6 heavy chain, ... | | Authors: | Wang, X, Zhang, L, Zhang, S, Liang, Q. | | Deposit date: | 2021-08-04 | | Release date: | 2022-04-27 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | RBD trimer mRNA vaccine elicits broad and protective immune responses against SARS-CoV-2 variants.
Iscience, 25, 2022
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1U37
 | | Auto-inhibition Mechanism of X11s/Mints Family Scaffold Proteins Revealed by the Closed Conformation of the Tandem PDZ Domains | | Descriptor: | amyloid beta A4 precursor protein-binding, family A, member 1 | | Authors: | Feng, W, Long, J.-F, Chan, L.-N, He, C, Fu, A, Xia, J, Ip, N.Y, Zhang, M. | | Deposit date: | 2004-07-21 | | Release date: | 2005-07-26 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Autoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandem
Nat.Struct.Mol.Biol., 12, 2005
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5XVF
 | | Crystal Structure of PAK4 in complex with inhibitor CZH062 | | Descriptor: | 2-(4-azanylpiperidin-1-yl)-6-chloranyl-N-(1-methylimidazol-4-yl)quinazolin-4-amine, Serine/threonine-protein kinase PAK 4 | | Authors: | Zhao, F, Li, H. | | Deposit date: | 2017-06-27 | | Release date: | 2018-02-07 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.655 Å) | | Cite: | Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors.
J. Med. Chem., 61, 2018
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1U39
 | | Auto-inhibition Mechanism of X11s/Mints Family Scaffold Proteins Revealed by the Closed Conformation of the Tandem PDZ Domains | | Descriptor: | amyloid beta A4 precursor protein-binding, family A, member 1 | | Authors: | Feng, W, Long, J.-F, Chan, L.-N, He, C, Fu, A, Xia, J, Ip, N.Y, Zhang, M. | | Deposit date: | 2004-07-21 | | Release date: | 2005-07-26 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Autoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandem
Nat.Struct.Mol.Biol., 12, 2005
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5Y38
 | | Crystal structure of C7orf59-HBXIP complex | | Descriptor: | Ragulator complex protein LAMTOR4, Ragulator complex protein LAMTOR5, SULFATE ION | | Authors: | Zhang, T, Ding, J. | | Deposit date: | 2017-07-28 | | Release date: | 2017-12-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for Ragulator functioning as a scaffold in membrane-anchoring of Rag GTPases and mTORC1
Nat Commun, 8, 2017
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6LAD
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6LAF
 | | Crystal structure of the core domain of Amuc_1100 from Akkermansia muciniphila | | Descriptor: | Amuc_1100, SULFATE ION | | Authors: | Wang, J, Xiang, R, Zhang, M, Wang, M. | | Deposit date: | 2019-11-12 | | Release date: | 2020-08-05 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.001 Å) | | Cite: | The variable oligomeric state of Amuc_1100 from Akkermansia muciniphila.
J.Struct.Biol., 212, 2020
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8PWW
 | | PfRH5 bound to monoclonal antibody MAD8-151 | | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | | Authors: | Farrell, B, Higgins, M.K. | | Deposit date: | 2023-07-21 | | Release date: | 2024-06-05 | | Last modified: | 2024-12-18 | | Method: | X-RAY DIFFRACTION (1.945 Å) | | Cite: | Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5.
Cell, 187, 2024
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8PWU
 | | PfRH5 bound to monoclonal antibody MAD10-255 | | Descriptor: | Reticulocyte-binding protein homolog 5, monoclonal antibody MAD10-255 | | Authors: | Farrell, B, Higgins, M.K. | | Deposit date: | 2023-07-21 | | Release date: | 2024-06-05 | | Last modified: | 2024-12-18 | | Method: | X-RAY DIFFRACTION (3.148 Å) | | Cite: | Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5.
Cell, 187, 2024
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8Q5D
 | | PfRH5 bound to monoclonal antibody MAD10-466 | | Descriptor: | Monoclonal antibody MAD10-466 heavy chain, Monoclonal antibody MAD10-466 light chain, Reticulocyte-binding protein homolog 5 | | Authors: | Farrell, B, Higgins, M.K. | | Deposit date: | 2023-08-08 | | Release date: | 2024-06-05 | | Last modified: | 2024-12-18 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5.
Cell, 187, 2024
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8PWV
 | | PfRH5 bound to monoclonal antibody MAD8-502 | | Descriptor: | Reticulocyte-binding protein homolog 5, monoclonal antibody MAD8-502 | | Authors: | Farrell, B, Higgins, M.K. | | Deposit date: | 2023-07-21 | | Release date: | 2024-06-05 | | Last modified: | 2024-12-18 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5.
Cell, 187, 2024
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8PWX
 | | PfRH5 bound to monoclonal antibody R5.008 | | Descriptor: | GLYCEROL, Reticulocyte-binding protein homolog 5, scFv fragment for antibody R5.008 | | Authors: | Farrell, B, Higgins, M.K. | | Deposit date: | 2023-07-21 | | Release date: | 2024-06-05 | | Last modified: | 2024-12-18 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5.
Cell, 187, 2024
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7FJC
 | | Crystal structure of SARS-CoV-2 Beta RBD complexed with P36-5D2 Fab | | Descriptor: | P36-5D2 heavy chain, P36-5D2 light chain, Spike protein S1, ... | | Authors: | Zhang, L.Q, Wang, X.Q, Shan, S.S, Lan, J. | | Deposit date: | 2021-08-03 | | Release date: | 2022-08-10 | | Last modified: | 2025-06-18 | | Method: | X-RAY DIFFRACTION (2.96 Å) | | Cite: | A Potent and Protective Human Neutralizing Antibody Against SARS-CoV-2 Variants.
Front Immunol, 12, 2021
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6LHE
 | | Crystal Structure of Gold-bound NDM-1 | | Descriptor: | GOLD ION, Metallo-beta-lactamase type 2, SULFATE ION | | Authors: | Wang, H, Sun, H, Wang, M. | | Deposit date: | 2019-12-07 | | Release date: | 2020-09-16 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.206 Å) | | Cite: | Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin.
Nat Commun, 11, 2020
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6LI4
 | | Crystal structure of MCR-1-S | | Descriptor: | Probable phosphatidylethanolamine transferase Mcr-1, ZINC ION | | Authors: | Zhang, Q, Wang, M, Sun, H. | | Deposit date: | 2019-12-10 | | Release date: | 2020-09-16 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.78 Å) | | Cite: | Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin.
Nat Commun, 11, 2020
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6LI5
 | | Crystal structure of apo-MCR-1-S | | Descriptor: | Probable phosphatidylethanolamine transferase Mcr-1 | | Authors: | Zhang, Q, Wang, M, Sun, H. | | Deposit date: | 2019-12-10 | | Release date: | 2020-09-16 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin.
Nat Commun, 11, 2020
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7FAW
 | | Structure of LW domain from Yeast | | Descriptor: | Transcription elongation factor S-II | | Authors: | Liao, S, Gao, J, Tu, X. | | Deposit date: | 2021-07-07 | | Release date: | 2022-07-13 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.438 Å) | | Cite: | Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.
Int.J.Biol.Macromol., 253, 2023
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7FAX
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4D90
 | | Crystal Structure of Del-1 EGF domains | | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Chen, Q, Schurpf, T, Springer, T, Wang, J. | | Deposit date: | 2012-01-11 | | Release date: | 2012-05-30 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.601 Å) | | Cite: | The RGD finger of Del-1 is a unique structural feature critical for integrin binding.
Faseb J., 26, 2012
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9JK4
 | | putative E2P of TMEM94 | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endoplasmic reticulum magnesium-transporting P-type ATPase | | Authors: | Gong, D.S. | | Deposit date: | 2024-09-15 | | Release date: | 2025-06-11 | | Method: | ELECTRON MICROSCOPY (2.82 Å) | | Cite: | Structural analysis of full-length human transmembrane protein 94 argues against its classification as a P-type Mg 2+ ATPase.
Cell Discov, 11, 2025
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9JK3
 | | putative MgE2P of TMEM94 | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endoplasmic reticulum magnesium-transporting P-type ATPase | | Authors: | Gong, D.S. | | Deposit date: | 2024-09-14 | | Release date: | 2025-06-11 | | Method: | ELECTRON MICROSCOPY (2.45 Å) | | Cite: | Structural analysis of full-length human transmembrane protein 94 argues against its classification as a P-type Mg 2+ ATPase.
Cell Discov, 11, 2025
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9JJN
 | | putative MgE1-ATP of human TMEM94 | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endoplasmic reticulum magnesium-transporting P-type ATPase | | Authors: | Gong, D.S. | | Deposit date: | 2024-09-14 | | Release date: | 2025-06-11 | | Method: | ELECTRON MICROSCOPY (2.49 Å) | | Cite: | Structural analysis of full-length human transmembrane protein 94 argues against its classification as a P-type Mg 2+ ATPase.
Cell Discov, 11, 2025
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9JJO
 | | putative MgE1P-ADP of human TMEM94 | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Endoplasmic reticulum magnesium-transporting P-type ATPase | | Authors: | Gong, D.S. | | Deposit date: | 2024-09-14 | | Release date: | 2025-06-11 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | Structural analysis of full-length human transmembrane protein 94 argues against its classification as a P-type Mg 2+ ATPase.
Cell Discov, 11, 2025
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9JK5
 | | putative MgE1-ATP-H of TMEM94 | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Endoplasmic reticulum magnesium-transporting P-type ATPase | | Authors: | Gong, D.S. | | Deposit date: | 2024-09-15 | | Release date: | 2025-06-11 | | Method: | ELECTRON MICROSCOPY (2.92 Å) | | Cite: | Structural analysis of full-length human transmembrane protein 94 argues against its classification as a P-type Mg 2+ ATPase.
Cell Discov, 11, 2025
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