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7EY0
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BU of 7ey0 by Molmil
Local CryoEM structure of the SARS-CoV-2 S6PV2 in complex with BD-813 Fab and BD-744 Fab
Descriptor: BD-744H, BD-744L, BD-813H, ...
Authors:Du, S, Xiao, J.
Deposit date:2021-05-29
Release date:2021-09-08
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of SARS-CoV-2 B.1.351 neutralizing antibodies provide insights into cocktail design against concerning variants.
Cell Res., 31, 2021
7DH3
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BU of 7dh3 by Molmil
The co-crystal structure of DYRK2 with a small molecule inhibitor 5
Descriptor: 2,7-dimethoxy-9-piperidin-4-ylsulfanyl-acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2
Authors:Wei, T, Xiao, J.
Deposit date:2020-11-12
Release date:2021-11-17
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:The co-crystal structure of DYRK2 with a small molecule inhibitor 5
To Be Published
7DNR
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BU of 7dnr by Molmil
Crystal Structure of Zn-bound SIS Domain of Glucosamine-6-P Synthase from E. coli
Descriptor: Glutamine--fructose-6-phosphate aminotransferase [isomerizing], ZINC ION
Authors:Gao, C, Xiao, J.
Deposit date:2020-12-10
Release date:2021-12-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of Metal-binding Proteins by Thermal Proteome Profiling
To Be Published
7DXI
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BU of 7dxi by Molmil
Structure of Drosophila melanogaster GlcNAc-1-phosphotransferase
Descriptor: CALCIUM ION, FI02838p
Authors:Du, S, Xiao, J, Guopeng, W.
Deposit date:2021-01-19
Release date:2022-02-02
Last modified:2022-08-17
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Structural insights into how GlcNAc-1-phosphotransferase directs lysosomal protein transport.
J.Biol.Chem., 298, 2022
5GS9
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BU of 5gs9 by Molmil
Crystal structure of CASTOR1-arginine
Descriptor: ARGININE, GATS-like protein 3
Authors:Zhang, T, Ding, J.
Deposit date:2016-08-15
Release date:2016-09-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insight into the arginine-binding specificity of CASTOR1 in amino acid-dependent mTORC1 signaling.
Cell Discov, 2, 2016
7VMZ
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BU of 7vmz by Molmil
Crystal structure of a human Coronavirus 229E antibody C04 Fab
Descriptor: C04 Fab Heavy Chain, C04 Fab Light Chain
Authors:Xiang, J.C, Yang, B.
Deposit date:2021-10-10
Release date:2022-10-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Antigenic mapping reveals sites of vulnerability on alpha-HCoV spike protein.
Commun Biol, 5, 2022
7VNG
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BU of 7vng by Molmil
Crystal structure of human coronavirus 229E spike protein receptor-binding domain in complex with S11 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, S11 Fab heavy chain, S11 Fab light chain, ...
Authors:Xiang, J.C, Zhao, W.W, Yang, B.
Deposit date:2021-10-11
Release date:2022-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Antigenic mapping reveals sites of vulnerability on alpha-HCoV spike protein.
Commun Biol, 5, 2022
7VN9
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BU of 7vn9 by Molmil
Crystal structure of human coronavirus 229E spike protein receptor-binding domain in complex with C04 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C04 Fab heavy chain, ...
Authors:Xiang, J.C, Yang, B.
Deposit date:2021-10-10
Release date:2022-10-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (4.49 Å)
Cite:Antigenic mapping reveals sites of vulnerability on alpha-HCoV spike protein.
Commun Biol, 5, 2022
6ITM
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BU of 6itm by Molmil
Crystal structure of FXR in complex with agonist XJ034
Descriptor: 1-adamantyl-[4-(5-chloranyl-2-methyl-phenyl)piperazin-1-yl]methanone, Bile acid receptor, HD3 Peptide from Nuclear receptor coactivator 1
Authors:Zhang, H, Wang, Z.
Deposit date:2018-11-23
Release date:2019-11-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Pose Filter-Based Ensemble Learning Enables Discovery of Orally Active, Nonsteroidal Farnesoid X Receptor Agonists.
J.Chem.Inf.Model., 60, 2020
2G92
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BU of 2g92 by Molmil
Crystal Structure Analysis of the RNA Dodecamer CGC-(NF2)-AAUUAGCG, with an Incorporated 2,4-Difluorotoluyl Residue (NF2)
Descriptor: 5'-R(*CP*GP*CP*(NF2)P*AP*AP*UP*UP*AP*GP*CP*G)-3'
Authors:Egli, M, Li, F.
Deposit date:2006-03-04
Release date:2006-04-18
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Gene silencing activity of siRNAs with a ribo-difluorotoluyl nucleotide.
Acs Chem.Biol., 1, 2006
5F1I
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BU of 5f1i by Molmil
MHC with 9-mer peptide
Descriptor: 9-mer peptide, Beta2M, MHC class I DLA-88
Authors:Liu, J, Chai, Y, QI, J, Gao, G.F.
Deposit date:2015-11-30
Release date:2016-11-30
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.904 Å)
Cite:Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I
J Immunol., 197, 2016
5F1N
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BU of 5f1n by Molmil
MHC complexed to 11mer peptide
Descriptor: Beta-2-microglobulin, MHC class I antigen, Peptide from Cytochrome P450 family 1 subfamily B polypeptide 1
Authors:Liu, J, Chai, Y, Qi, J, Gao, G.F.
Deposit date:2015-11-30
Release date:2016-11-30
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Diversified Anchoring Features the Peptide Presentation of DLA-88*50801: First Structural Insight into Domestic Dog MHC Class I
J Immunol., 197, 2016
5GJ9
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BU of 5gj9 by Molmil
Crystal structure of Arabidopsis thaliana ACO2 in complex with POA
Descriptor: 1-aminocyclopropane-1-carboxylate oxidase 2, PYRAZINE-2-CARBOXYLIC ACID, ZINC ION
Authors:Sun, X.Z, Li, Y.X, He, W.R, Ji, C.G, Xia, P.X, Wang, Y.C, Du, S, Li, H.J, Raikhel, N, Xiao, J.Y, Guo, H.W.
Deposit date:2016-06-28
Release date:2017-05-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Pyrazinamide and derivatives block ethylene biosynthesis by inhibiting ACC oxidase.
Nat Commun, 8, 2017
5GJA
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BU of 5gja by Molmil
Crystal structure of Arabidopsis thaliana ACO2 in complex with 2-PA
Descriptor: 1-aminocyclopropane-1-carboxylate oxidase 2, PYRIDINE-2-CARBOXYLIC ACID, ZINC ION
Authors:Sun, X.Z, Li, Y.X, He, W.R, Ji, C.G, Xia, P.X, Wang, Y.C, Du, S, Li, H.J, Raikhel, N, Xiao, J.Y, Guo, H.W.
Deposit date:2016-06-28
Release date:2017-05-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Pyrazinamide and derivatives block ethylene biosynthesis by inhibiting ACC oxidase.
Nat Commun, 8, 2017
8JQ9
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BU of 8jq9 by Molmil
Novel Anti-phage System
Descriptor: Endonuclease GajA
Authors:Li, J, Wang, Z, Wang, L.
Deposit date:2023-06-13
Release date:2024-02-28
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8JQB
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BU of 8jqb by Molmil
Structure of Gabija GajA-GajB 4:4 Complex
Descriptor: Endonuclease GajA, Gabija protein GajB
Authors:Li, J, Wang, Z, Wang, L.
Deposit date:2023-06-13
Release date:2024-02-28
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8JQC
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BU of 8jqc by Molmil
Novel Anti-phage System
Descriptor: Endonuclease GajA, Gabija protein GajB
Authors:Li, J, Wang, Z, Wang, L.
Deposit date:2023-06-13
Release date:2024-02-28
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8WY4
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BU of 8wy4 by Molmil
GajA tetramer with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA
Authors:Li, J, Wang, Z, Wang, L.
Deposit date:2023-10-30
Release date:2024-02-28
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.81 Å)
Cite:Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8X5I
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BU of 8x5i by Molmil
tetramer Gabija with ATP (local refinement)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA, MAGNESIUM ION
Authors:Li, J, Wang, Z, Wang, L.
Deposit date:2023-11-17
Release date:2024-02-28
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.01 Å)
Cite:Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8X5N
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BU of 8x5n by Molmil
Tetramer Gabija with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA, Gabija protein GajB, ...
Authors:Li, J, Wang, Z, Wang, L.
Deposit date:2023-11-17
Release date:2024-02-28
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8X51
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BU of 8x51 by Molmil
Cryo-EM structure of Gabija GajA in complex with DNA(focused refinement)
Descriptor: CALCIUM ION, DNA (5'-D(*AP*AP*AP*AP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*TP*AP*TP*TP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*TP*AP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*TP*TP*TP*T)-3'), ...
Authors:Li, J, Wang, Z, Wang, L.
Deposit date:2023-11-16
Release date:2024-02-28
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
8WY5
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BU of 8wy5 by Molmil
Structure of Gabija GajA in complex with DNA
Descriptor: CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*TP*AP*TP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*AP*AP*TP*AP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*TP*TP*T)-3'), ...
Authors:Li, J, Wang, Z, Wang, L.
Deposit date:2023-10-30
Release date:2024-02-28
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
4MQV
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BU of 4mqv by Molmil
Crystal complex of Rpa32c and Smarcal1 N-terminus
Descriptor: Replication protein A 32 kDa subunit, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1
Authors:Xie, S, Qian, C.M.
Deposit date:2013-09-16
Release date:2014-07-02
Last modified:2014-12-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structure of RPA32 bound to the N-terminus of SMARCAL1 redefines the binding interface between RPA32 and its interacting proteins
Febs J., 281, 2014
7WP6
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BU of 7wp6 by Molmil
Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK in complex with three neutralizing antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 36H6 heavy chain, ...
Authors:Zheng, Q, Sun, H, Yuan, Q, Li, S, Xia, N.
Deposit date:2022-01-23
Release date:2023-03-01
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine.
Cell Host Microbe, 30, 2022
7WP8
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BU of 7wp8 by Molmil
Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK1628x in complex with three neutralizing antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 heavy chain, ...
Authors:Zheng, Q, Sun, H, Yuan, Q, Li, S, Xia, N.
Deposit date:2022-01-23
Release date:2023-03-08
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (3.88 Å)
Cite:Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine.
Cell Host Microbe, 30, 2022

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数据于2024-10-09公开中

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